Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Yong‐Seok Song"'
Autor:
Christine M Sorenson, Zafer Gurel, Yong-Seok Song, Kyle D Peterson, Barbara A Blodi, Nader Sheibani
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297135 (2024)
Age-related macular degeneration (AMD) is a vision threatening disease in older adults. Anti-VEGF treatment is effective for the majority of neovascular AMD (nAMD) patients, although approximately 30% of nAMD patients have an incomplete response for
Externí odkaz:
https://doaj.org/article/aac38f7c859d491182daf612a28022c1
Publikováno v:
Cells, Vol 13, Iss 1, p 50 (2023)
Age-related macular degeneration (AMD) remains a leading cause of vision loss in elderly patients. Its etiology and progression are, however, deeply intertwined with various cellular and molecular interactions within the retina and choroid. Among the
Externí odkaz:
https://doaj.org/article/29c777ec284b4569bd925e116556078b
Autor:
Collin P. Goebel, Yong-Seok Song, Ismail S. Zaitoun, Shoujian Wang, Heather A. D. Potter, Christine M. Sorenson, Nader Sheibani
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 18, Iss 1, Pp 1-2 (2023)
Abstract Purpose: Adenosine signaling modulates ocular inflammatory processes, and its antagonism mitigates neovascularization in both newborns and preclinical models of ocular neovascularization including age-related macular degeneration (AMD). The
Externí odkaz:
https://doaj.org/article/c924fab79dc843118d8057f506cd15ed
Publikováno v:
Cells, Vol 12, Iss 2, p 335 (2023)
The integrity of retinal endothelial cell (EC) is essential for establishing and maintaining the retinal blood barrier to ensure proper vision. Vitamin D is a hormone with known protective roles in EC function. The majority of vitamin D action is med
Externí odkaz:
https://doaj.org/article/1707305b29f048aab833474b6861d96c
Autor:
Christine M. Sorenson, Yong-Seok Song, Ismail S. Zaitoun, Shoujian Wang, Barbara A. Hanna, Soesiawati R. Darjatmoko, Zafer Gurel, Debra L. Fisk, Colleen M. McDowell, Ryan M. McAdams, Nader Sheibani
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Adenosine receptors (AR) are widely expressed in a variety of tissues including the retina and brain. They are involved in adenosine-mediated immune responses underlying the onset and progression of neurodegenerative diseases. The expression of AR ha
Externí odkaz:
https://doaj.org/article/02459f7142584f92902c60fc09be27df
Assessment of Choroidal Vasculature and Innate Immune Cells in the Eyes of Albino and Pigmented Mice
Publikováno v:
Cells, Vol 11, Iss 20, p 3329 (2022)
The visualization of choroidal vasculature and innate immune cells in the eyes of pigmented mice has been challenging due to the presence of a retinal pigment epithelium (RPE) layer separating the choroid and retina. Here, we established methods for
Externí odkaz:
https://doaj.org/article/a3d27e259e6b496d96a45a9540c124de
Publikováno v:
FASEB BioAdvances, Vol 1, Iss 7, Pp 415-434 (2019)
Abstract We have previously demonstrated that the active form of vitamin D (calcitriol; 1,25(OH)2D3) is a potent inhibitor of retinal neovascularization. However, the underlying molecular and cellular mechanisms involved remained poorly understood. P
Externí odkaz:
https://doaj.org/article/793d689a6c044ca6a9eb18f6cdf34b76
Autor:
Christine M. Sorenson, Yong-Seok Song, Shoujian Wang, Soesiawati R. Darjatmoko, Mohammad Ali Saghiri, Mahsa Ranji, Nader Sheibani
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1295 (2022)
Branching morphogenesis is a key developmental process during organogenesis, such that its disruption frequently leads to long-term consequences. The kidney and eye share many etiologies, perhaps, due to similar use of developmental branching morphog
Externí odkaz:
https://doaj.org/article/b085eb214ddd4c9f80a28b9d192d59a0
Autor:
Yong-Seok Song, Andrew J. Annalora, Craig B. Marcus, Colin R. Jefcoate, Christine M. Sorenson, Nader Sheibani
Publikováno v:
Cells, Vol 11, Iss 19, p 2930 (2022)
Cytochrome P450 (CYP) 1B1 belongs to the superfamily of heme-containing monooxygenases. Unlike other CYP enzymes, which are highly expressed in the liver, CYP1B1 is predominantly found in extrahepatic tissues, such as the brain, and ocular tissues in
Externí odkaz:
https://doaj.org/article/9af53ceee1f7409fb7e079fd002d9406
Autor:
Ismail S Zaitoun, Yong-Seok Song, Andrew Suscha, Mohamed El Ragaby, Christine M Sorenson, Nader Sheibani
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0260793 (2021)
Retinopathy of prematurity (ROP) is one of the main causes of blindness in children worldwide. Brain-derived neurotrophic factor (BDNF) and its receptor, tropomyosin-related kinase B (TrkB), play critical protective roles in the development and funct
Externí odkaz:
https://doaj.org/article/d43fd94c7bf1461ab5d50e0a7217a8d3