Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yong‐Ping Jian"'
Autor:
Yuan Zhao, Meng-Jie Liu, Lei Zhang, Qi Yang, Qian-Hui Sun, Jin-Rong Guo, Xin-Yuan Lei, Kai-Yue He, Jun-Qi Li, Jing-Yu Yang, Yong-Ping Jian, Zhi-Xiang Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Metabolic reprogramming is a hallmark of cancer, enabling tumor cells to meet the high energy and biosynthetic demands required for their proliferation. High mobility group A1 (HMGA1) is a structural transcription factor and frequently overe
Externí odkaz:
https://doaj.org/article/4d0d403ebbdf4f05a0d6a47c22faacaa
Autor:
Meng-Jie Liu, Yuan Zhao, Qiu-Tong Li, Xin-Yuan Lei, Kai-Yue He, Jin-Rong Guo, Jing-Yu Yang, Zhen-Hua Yan, Dan-Hui Wu, Lei Zhang, Yong-Ping Jian, Zhi-Xiang Xu
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-15 (2024)
Abstract Esophageal squamous cell carcinoma (ESCC) possesses a poor prognosis and treatment outcome. Dysregulated metabolism contributes to unrestricted growth of multiple cancers. However, abnormal metabolism, such as highly activated pentose phosph
Externí odkaz:
https://doaj.org/article/fdcf8b824da241419a86937b0cfaf446
Autor:
Jing-Yu Yang, Xin-Yuan Lei, Kai-Yue He, Jin-Rong Guo, Meng-Jie Liu, Jun-Qi Li, Qiu-Tong Li, Zhi-Hao Jiang, Lei Zhang, Dan-Hui Wu, Yu-Jia Li, Qian-Hui Sun, Yong-Ping Jian, Zhi-Xiang Xu
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-16 (2024)
Abstract Chemotherapy is a primary treatment for esophageal squamous cell carcinoma (ESCC). Resistance to chemotherapeutic drugs is an important hurdle to effective treatment. Understanding the mechanisms underlying chemotherapy resistance in ESCC is
Externí odkaz:
https://doaj.org/article/d9895485b3a64bd58022048ca442b56f
Autor:
Dan Zhang, Yong-Ping Jian, Yu-Ning Zhang, Yao Li, Li-Ting Gu, Hui-Hui Sun, Ming-Di Liu, Hong-Lan Zhou, Yi-Shu Wang, Zhi-Xiang Xu
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate transporters, such as monocarboxylate transporter 1
Externí odkaz:
https://doaj.org/article/0eb07073efc94818828064dcf29589f0
Autor:
Kai-Yue He, Xin-Yuan Lei, Lei Zhang, Dan-Hui Wu, Jun-Qi Li, Li-Yuan Lu, Umm E. Laila, Cui-Yun Cui, Zhi-Xiang Xu, Yong-Ping Jian
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
BackgroundEmerging evidence reveals that SARS-CoV-2 possesses the capability to disrupt the gastrointestinal (GI) homeostasis, resulting in the long-term symptoms such as loss of appetite, diarrhea, gastroesophageal reflux, and nausea. In the current
Externí odkaz:
https://doaj.org/article/91553cb40e5e44f6a5ad16f9c4899279
Autor:
Kai-Yue He, Xin-Yuan Lei, Dan-Hui Wu, Lei Zhang, Jun-Qi Li, Qiu-Tong Li, Wei-Tao Yin, Zi-Long Zhao, Huai Liu, Xiong-Yan Xiang, Ling-Jun Zhu, Cui-Yun Cui, Ke-Ke Wang, Jin-Hua Wang, Lin Lv, Qian-Hui Sun, Guo-Long Liu, Zhi-Xiang Xu, Yong-Ping Jian
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTIntestinal dysbiosis frequently occurs in abdominal radiotherapy and contributes to irradiation (IR)-induced intestinal damage and inflammation. Akkermansia muciniphila (A. muciniphila) is a recently characterized probiotic, which is critical
Externí odkaz:
https://doaj.org/article/6917afcec6f14cffa232d8e6090f31c7
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/8495ed87746b49c8a710afd3debb119f
Autor:
Jing-Yu Yang, Meng-Jie Liu, Lin Lv, Jin-Rong Guo, Kai-Yue He, Hong Zhang, Ke-Ke Wang, Cui-Yun Cui, Bei-Zhan Yan, Dan-Dan Du, Jin-Hua Wang, Qiang Ding, Guo-Long Liu, Zhi-Xiang Xu, Yong-Ping Jian
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Abdominal irradiation (IR) destroys the intestinal mucosal barrier, leading to severe intestinal infection. There is an urgent need to find safe and effective treatments to reduce IR-induced intestinal injury. In this study, we reported that metformi
Externí odkaz:
https://doaj.org/article/7bfff439c0a34179af14b42eb337fd02
Autor:
Ke-Ke Wang, Kai-Yue He, Jing-Yu Yang, Meng-Jie Liu, Jin-Rong Guo, Ji-Yong Liang, Jin-Hua Wang, Zhi-Xiang Xu, Yong-Ping Jian
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Deficiency in T cell-mediated adaptive immunity, such as low CD8+ T cell infiltration, inhibits the immune surveillance, promotes malignant transformation, and facilitates tumor growth. Microbiota dysbiosis diminishes the immune system and contribute
Externí odkaz:
https://doaj.org/article/a97db16c3974454596e7f422b53ab76a
Autor:
Qian-Hui Sun, Yi-Shu Wang, Guolong Liu, Hong-Lan Zhou, Yong-Ping Jian, Ming-Di Liu, Dan Zhang, Qiang Ding, Rui-Xun Zhao, Jian-Feng Chen, Yi-Ning Li, Jiyong Liang, Yu-Lin Li, Cheng-Shi Quan, Zhi-Xiang Xu
Publikováno v:
EBioMedicine, Vol 53, Iss , Pp - (2020)
Background: Treatment of Crohn's disease (CD) remains to be a challenge due to limited insights for its pathogenesis. We aimed to determine the role of O-Linked β-N-acetylglucosamine (O-GlcNAc) in the development of CD and evaluate therapeutic effec
Externí odkaz:
https://doaj.org/article/4b9e38c85ca54b078c52a29c2fd8865a