Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yong‐Hyun Han"'
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-12 (2024)
Abstract Background Concurrent emerging and reemerging avian infectious diseases cause multiple risk factors in poultry. A body amount studies attempted to understand pathogen-associated immunity in chickens. Recent research has made progress in iden
Externí odkaz:
https://doaj.org/article/366415308b3a429e9e399049b0d76aa5
Autor:
Nam-Hee Kim, Seung-Jin Lee, Kyeong-Jin Lee, Ae Ri Song, Hyun-Je Park, Jong Soo Kang, Joo Young Cha, Yong-Hyun Han
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5881-5893 (2024)
Nonalcoholic steatohepatitis (NASH) is characterized by severe inflammation and fibrosis due to an excessive accumulation of triglycerides (TGs) in the liver with a dysregulated de novo lipogenesis (DNL) pathway. In this study, we aimed to evaluate t
Externí odkaz:
https://doaj.org/article/20f531cdf7b041219e8a334694103c61
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 615-630 (2024)
Abstract Background Fat infiltration in muscle, called ‘myosteatosis’, precedes muscle atrophy, which subsequently results in sarcopenia. Myosteatosis is frequently observed in patients with nonalcoholic fatty liver disease (NAFLD). We have previ
Externí odkaz:
https://doaj.org/article/b442553b3f8e4254a04a307a2aceb60d
Autor:
Dong-Hyun Kim, Kyeong-Jin Lee, JinJoo Park, Susan Chi, Jaekyu Han, Yewon Bang, Sun-Mi Kim, Seung Goo Kang, Sang-Hoon Cha, Yong-Hyun Han
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115587- (2023)
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive inflammation and fibrosis around intrahepatic and extrahepatic bile ducts leading to severe hepatic cirrhosis and high mortality. Although there
Externí odkaz:
https://doaj.org/article/345c4fb9891b45f9a684528372adcdf1
Autor:
Emily J. Onufer, Rafael S. Czepielewski, Yong-Hyun Han, Cathleen M. Courtney, Stephanie Sutton, Anne Sescleifer, Gwendalyn J. Randolph, Brad W. Warner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Short bowel syndrome (SBS) is associated with diminished levels of serum fats caused by unknown mechanisms. We have shown that mesenteric lymphatics remodel to a more primitive state one week after small bowel resection (SBR); therefore, thi
Externí odkaz:
https://doaj.org/article/2e0a928a45014113a18801a719740391
Publikováno v:
Hepatology Communications, Vol 5, Iss 12, Pp 2121-2138 (2021)
Lysosomes are intracellular acidic organelles with catabolic functions that contribute to the activation of autophagy. Although autophagy abnormality is associated with defects in lysosomal acidification during the progression of nonalcoholic fatty l
Externí odkaz:
https://doaj.org/article/50f230311ab34304a7a6483c380a92df
Autor:
Yong-Hyun Han, Hyeon-Ji Kim, Hyelin Na, Min-Woo Nam, Ju-Yeon Kim, Jun-Seok Kim, Seung-Hoi Koo, Mi-Ock Lee
Publikováno v:
Cell Reports, Vol 20, Iss 1, Pp 124-135 (2017)
The regulation of M1/M2 polarization in liver macrophages is closely associated with the progression of nonalcoholic steatohepatitis (NASH); however, the mechanism involved in this process remains unclear. Here, we describe the orphan nuclear recepto
Externí odkaz:
https://doaj.org/article/0bbd9f18edfa4014b44b344957215e5d
Autor:
Kyeong‐Jin Lee, Seungchan An, Mi‐Yeon Kim, Sun Myoung Kim, Won‐Il Jeong, Hyun‐Jeong Ko, Yoon Mee Yang, Minsoo Noh, Yong‐Hyun Han
Publikováno v:
Immunology & Cell Biology. 101:216-230
Loss of ERdj5 exacerbates oxidative stress in mice with alcoholic liver disease via suppressing Nrf2
Autor:
Dong-Gyun Hong, Ga Yeon Song, Cheol Bin Eom, Jae-Hee Ahn, Sun Myoung Kim, Aeri Shim, Yong-Hyun Han, Yoon-Seok Roh, Chang Yeob Han, Eun Ju Bae, Hyun-Jeong Ko, Yoon Mee Yang
Publikováno v:
Free Radical Biology and Medicine. 184:42-52
Alcoholic liver disease is the major cause of chronic liver diseases. Excessive alcohol intake results in endoplasmic reticulum (ER) stress. ERdj5, a member of DNAJ family, is an ER-resident chaperone protein, whose role in alcoholic liver disease re
Publikováno v:
BMB Reports. 55:166-174