Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Yong‐Hui Jiang"'
Autor:
Yudong Gao, Daichi Shonai, Matthew Trn, Jieqing Zhao, Erik J. Soderblom, S. Alexandra Garcia-Moreno, Charles A. Gersbach, William C. Wetsel, Geraldine Dawson, Dmitry Velmeshev, Yong-hui Jiang, Laura G. Sloofman, Joseph D. Buxbaum, Scott H. Soderling
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract One of the main drivers of autism spectrum disorder is risk alleles within hundreds of genes, which may interact within shared but unknown protein complexes. Here we develop a scalable genome-editing-mediated approach to target 14 high-confi
Externí odkaz:
https://doaj.org/article/f993b5c92d79459eb326486abfab23a3
Autor:
George D. Dalton, Stephen K. Siecinski, Viktoriya D. Nikolova, Gary P. Cofer, Kathryn J. Hornburg, Yi Qi, G. Allan Johnson, Yong-Hui Jiang, Sheryl S. Moy, Simon G. Gregory
Publikováno v:
Behavioral and Brain Functions, Vol 20, Iss 1, Pp 1-23 (2024)
Abstract Background Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders with higher incidence in males and is characterized by atypical verbal/nonverbal communication, restricted interests that can be accompanied by repetitive b
Externí odkaz:
https://doaj.org/article/3a0dc3d8da37446598bf596a2a78dc61
Autor:
Xiaona Lu, Pengyu Ni, Paola Suarez-Meade, Yu Ma, Emily Niemitz Forrest, Guilin Wang, Yi Wang, Alfredo Quiñones-Hinojosa, Mark Gerstein, Yong-hui Jiang
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114376- (2024)
Summary: Precision of transcription is critical because transcriptional dysregulation is disease causing. Traditional methods of transcriptional profiling are inadequate to elucidate the full spectrum of the transcriptome, particularly for longer and
Externí odkaz:
https://doaj.org/article/fc95a257f22349b9bb5b87d26085c896
Autor:
Autumn DiAdamo, Hongyan Chai, Mei Ling Chong, Guilin Wang, Jiadi Wen, Yong-Hui Jiang, Peining Li
Publikováno v:
Global Medical Genetics, Vol 11, Iss 01, Pp 123-131 (2024)
Background A retrospective study was performed to evaluate the patterns of cytogenomic findings detected from a case series of products of conception (POC) in recurrent pregnancy loss (RPL) over a 16-year period from 2007 to 2023.
Externí odkaz:
https://doaj.org/article/b5a57dd33fbc45bcafbbfdc3162cd114
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background SHANK3 gene is a highly replicated causative gene for autism spectrum disorder and has been well characterized in multiple Shank3 mutant rodent models. When compared to rodents, domestic dogs are excellent animal models in which t
Externí odkaz:
https://doaj.org/article/c33e2697ba1d414aa5290ce5fc5ff14d
Autor:
Jiawen Liao, Yi Zhang, Zhenchun Yang, Chenyu Qiu, Wu Chen, Junfeng Jim Zhang, Kiros Berhane, Zhipeng Bai, Bin Han, Jia Xu, Yong-hui Jiang, Frank Gilliland, Weili Yan, Guoying Huang, Zhanghua Chen
Publikováno v:
Environmental Health, Vol 22, Iss 1, Pp 1-14 (2023)
Abstract Background Few studies have assessed air pollution exposure association with birthweight during both preconception and gestational periods. Methods Leveraging a preconception cohort consisting of 14220 pregnant women and newborn children in
Externí odkaz:
https://doaj.org/article/758ee18f7365441492f70eb32d2e1e39
Autor:
Zakia Abdelhamed, Daniel Dykas, Autumn DiAdamo, Jai-Di Wen, Hui Zhang, Michele Spencer-Manzon, Peining Li, Yong-Hui Jiang, Allen Bale
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101508- (2024)
Externí odkaz:
https://doaj.org/article/b29eefdfda3a4640ad0e77343e2d061d
Autor:
Bang Li, Hui Zhao, Zhuchi Tu, Weili Yang, Rui Han, Lu Wang, Xiaopeng Luo, Mingtian Pan, Xiusheng Chen, Jiawei Zhang, Huijuan Xu, Xiangyu Guo, Sen Yan, Peng Yin, Zhiguang Zhao, Jianrong Liu, Yafeng Luo, Yuefeng Li, Zhengyi Yang, Baogui Zhang, Zhiqiang Tan, Hao Xu, Tianzi Jiang, Yong-hui Jiang, Shihua Li, Yong Q. Zhang, Xiao-Jiang Li
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-23 (2023)
Abstract Autism spectrum disorder (ASD) is a complex neurodevelopmental condition that affects social interaction and behavior. Mutations in the gene encoding chromodomain helicase DNA-binding protein 8 (CHD8) lead to autism symptoms and macrocephaly
Externí odkaz:
https://doaj.org/article/f4a0a5dc3c484d7ab32f386567e0b825
Autor:
Roman Thaler, Farzaneh Khani, Ines Sturmlechner, Sharareh S. Dehghani, Janet M. Denbeigh, Xianhu Zhou, Oksana Pichurin, Amel Dudakovic, Sofia S. Jerez, Jian Zhong, Jeong-Heon Lee, Ramesh Natarajan, Ivo Kalajzic, Yong-hui Jiang, David R. Deyle, Eleftherios P. Paschalis, Barbara M. Misof, Tamas Ordog, Andre J. van Wijnen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
For decades vitamin C’s primary function in bone has been attributed to its involvement in collagen synthesis. Here, the authors uncover that vitamin C’s central role in bone is to globally orchestrate osteogenesis via epigenetic mechanisms.
Externí odkaz:
https://doaj.org/article/03ddd7fcf25c4309b04599c7af2fbd14
Autor:
Gang Peng, Qinghua Zhou, Hongyan Chai, Jiadi Wen, Hongyu Zhao, Hugh S. Taylor, Yong‐Hui Jiang, Peining Li
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract A meta‐analysis on seven large case series (>1000 cases) of chromosome microarray analysis (CMA) on products of conceptions (POC) evaluated the diagnostic yields of genomic disorders and syndromic pathogenic copy number variants (pCNVs) fr
Externí odkaz:
https://doaj.org/article/b6114eb278a54495b6af068716582854