Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yonatan N. Degefu"'
Autor:
Nhi Van, Yonatan N. Degefu, Pathricia A. Leus, Jonah Larkins-Ford, Jacob Klickstein, Florian P. Maurer, David Stone, Husain Poonawala, Cheleste M. Thorpe, Trever C. Smith, Bree B. Aldridge
Mycobacterium abscessusinfections are difficult to treat and are often considered untreatable without tissue resection. Due to the intrinsic drug-resistant nature of the bacteria, combination therapy of three or more antibiotics is recommended. A maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ec1422fbece864d31cb24829334946
https://doi.org/10.1101/2022.12.12.520102
https://doi.org/10.1101/2022.12.12.520102
Publikováno v:
Cell reports. Medicine. 3(9)
A challenge in designing treatment regimens for tuberculosis is the necessity to use three or more antibiotics in combination. The combination space is too large to be comprehensively assayed; therefore, only a small number of possible combinations a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080a6917a0b394de45c1330122b3a2cd
https://pubmed.ncbi.nlm.nih.gov/36084643
https://pubmed.ncbi.nlm.nih.gov/36084643
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2314
Treatment of tuberculosis necessitates combination therapy. Therefore, development of new tuberculosis therapies should consider multidrug effects because specific combinations may improve or reduce treatment efficacy through synergistic or antagonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac255d1f6e4d547fbbe169ef2e4db871
https://pubmed.ncbi.nlm.nih.gov/34235676
https://pubmed.ncbi.nlm.nih.gov/34235676
Autor:
Talia Greenstein, Bree B. Aldridge, Michaela C. Olson, Nhi Van, Jonah Larkins-Ford, Artem Sokolov, Yonatan N. Degefu
A lengthy multidrug chemotherapy is required to achieve a durable cure in tuberculosis. Variation in Mycobacterium tuberculosis drug response is created by the differing microenvironments in lesions, which generate different bacterial drug susceptibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be6ccfef80530830f5cd87514c55a38e
https://doi.org/10.1101/2021.02.03.429579
https://doi.org/10.1101/2021.02.03.429579
Publikováno v:
Methods in Molecular Biology ISBN: 9781071614594
Treatment of tuberculosis necessitates combination therapy. Therefore, development of new tuberculosis therapies should consider multidrug effects because specific combinations may improve or reduce treatment efficacy through synergistic or antagonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7ab4b5db0965d539abeecd97c0e4e79
https://doi.org/10.1007/978-1-0716-1460-0_30
https://doi.org/10.1007/978-1-0716-1460-0_30
Autor:
Michaela C. Olson, Nhi Van, Jonah Larkins-Ford, Talia Greenstein, Bree B. Aldridge, Yonatan N. Degefu, Artem Sokolov
Publikováno v:
Cell Systems
Summary Lengthy multidrug chemotherapy is required to achieve a durable cure in tuberculosis. However, we lack well-validated, high-throughput in vitro models that predict animal outcomes. Here, we provide an extensible approach to rationally priorit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fd5422e6b0088b198c36d31d1756f0
http://europepmc.org/articles/PMC8617591
http://europepmc.org/articles/PMC8617591