Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yonatan B, Tzur"'
Autor:
Reut Shabtai, Yonatan B. Tzur
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The testis is the mammalian tissue with the highest expression levels of long intergenic non-coding RNAs (lincRNAs). However, most in vivo models have not found significant reductions in male fertility when highly expressed lincRNA genes were removed
Externí odkaz:
https://doaj.org/article/306862218520475096e0fe9b6981bc95
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
During meiosis, sex chromosomes show silenced gene expression that is disrupted when translocated to autosomes. Here, the authors engineer C. elegans with bisected X chromosomes and see active transcription in gonads, indicating continuity of sex chr
Externí odkaz:
https://doaj.org/article/b8c74cbf8faa449392cb3b9e02e9494e
Autor:
Yonatan B. Tzur
Publikováno v:
Trends in Genetics. 38:1170-1179
Comparative transcriptome approaches assume that highly or dynamically expressed genes are important. This has led to the identification of many genes critical for cellular activity and organism development. However, while testes express the highest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9763d937495a3b788d23a222a95bdc6e
https://doi.org/10.1016/j.tig.2022.05.013
https://doi.org/10.1016/j.tig.2022.05.013
Autor:
Lorna Moll, Noa Roitenberg, Michal Bejerano-Sagie, Hana Boocholez, Filipa Carvalhal Marques, Yuli Volovik, Tayir Elami, Atif Ahmed Siddiqui, Danielle Grushko, Adi Biram, Bar Lampert, Hana Achache, Tommer Ravid, Yonatan B Tzur, Ehud Cohen
Publikováno v:
eLife, Vol 7 (2018)
Although aging-regulating pathways were discovered a few decades ago, it is not entirely clear how their activities are orchestrated, to govern lifespan and proteostasis at the organismal level. Here, we utilized the nematode Caenorhabditis elegans t
Externí odkaz:
https://doaj.org/article/b31f6b8500b049b2928dc3c11f46757c
Autor:
Saravanapriah Nadarajan, Firaz Mohideen, Yonatan B Tzur, Nuria Ferrandiz, Oliver Crawley, Alex Montoya, Peter Faull, Ambrosius P Snijders, Pedro R Cutillas, Ashwini Jambhekar, Michael D Blower, Enrique Martinez-Perez, J Wade Harper, Monica P Colaiacovo
Publikováno v:
eLife, Vol 5 (2016)
Asymmetric disassembly of the synaptonemal complex (SC) is crucial for proper meiotic chromosome segregation. However, the signaling mechanisms that directly regulate this process are poorly understood. Here we show that the mammalian Rho GEF homolog
Externí odkaz:
https://doaj.org/article/4df71421871c44c4a4879464b70529bc
Autor:
Eyal Itskovits, Eitan Kroizer, Yisrael Rappaport, Yonatan B Tzur, Hila Gingold, Hasan Ishtayeh, Oded Rechavi, Corinne Best, Hanna Achache
Publikováno v:
RNA Biology. 18:435-445
Long intergenic non-coding RNAs (lincRNAs) are transcripts longer than 200 nucleotides that are transcribed from non-coding loci yet undergo biosynthesis similar to coding mRNAs. The disproportional number of lincRNAs expressed in testes suggests tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0028cd886dff94948a4f2daec2f16ec1
https://doi.org/10.1080/15476286.2020.1814549
https://doi.org/10.1080/15476286.2020.1814549
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
During meiosis, gene expression is silenced in aberrantly unsynapsed chromatin and in heterogametic sex chromosomes. Initiation of sex chromosome silencing is disrupted in meiocytes with sex chromosome-autosome translocations. To determine whether th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da211ad2f43c014cc6ede27db27c8700
https://doi.org/10.1038/s41467-021-24815-0
https://doi.org/10.1038/s41467-021-24815-0
Autor:
Yonatan B Tzur, Lévana Laurent, Yaël Hecker-Mimoun, Monica P. Colaiácovo, Eitan Kroizer, Yisrael Rappaport, Hanna Achache, Hasan Ishtayeh
Publikováno v:
Genetics. 212:213-229
During meiosis, a series of evolutionarily conserved events allow for reductional chromosome division, which is required for sexual reproduction. Although individual meiotic processes have been extensively studied, we currently know far less about ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5075b53d118c871c153e454d00cd8507
https://doi.org/10.1534/genetics.119.302080
https://doi.org/10.1534/genetics.119.302080
Publikováno v:
Aging Cell
Oogenesis is one of the first processes to fail during aging. In women, most oocytes cannot successfully complete meiotic divisions already during the fourth decade of life. Studies of the nematode Caenorhabditis elegans have uncovered conserved gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2537e3ba44cdb2daef0681232e1205cc
http://europepmc.org/articles/PMC8208789
http://europepmc.org/articles/PMC8208789
During meiosis of heterogametic cells, such as XY meiocytes, sex chromosomes of many species undergo transcriptional silencing known as meiotic sex chromosome inactivation (MSCI). Silencing also occurs in aberrantly unsynapsed autosomal chromatin. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e45645dec3d31542f1e05433867c55b3
https://doi.org/10.1101/2020.11.05.369132
https://doi.org/10.1101/2020.11.05.369132
