Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yona Shadkchan"'
Autor:
Mariana Handelman, Zohar Meir, Yona Shadkchan, Ammar Abo Kandil, Orin Amano, Melani Mariscal, Manuel Sánchez López-Berges, Nir Osherov
Publikováno v:
mSphere, Vol 9, Iss 6 (2024)
ABSTRACT Aspergillus fumigatus is the leading cause of severe mold infections in immunocompromised patients. This common fungus possesses innate attributes that allow it to evade the immune system, including its ability to survive the high copper (Cu
Externí odkaz:
https://doaj.org/article/37379d58dd98438eacd132bdb868ce27
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Aspergillus fumigatus is the primary mold pathogen in humans. It can cause a wide range of diseases in humans, with high mortality rates in immunocompromised patients. The first-line treatments for invasive A. fumigatus infections are the tr
Externí odkaz:
https://doaj.org/article/1670dc4980c149cf8e6a303acceb39df
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 1036-1049 (2018)
Background: Aspergillus fumigatus is the most prevalent airborne fungal pathogen, causing invasive fungal infections mainly in immunosuppressed individuals. Death rates from invasive aspergillosis remain high because of limited treatment options and
Externí odkaz:
https://doaj.org/article/23f3b1d224ee431eb16ddbcab880ad79
Publikováno v:
Medical Mycology. 60
S9.2 Azole resistance in Aspergillus fumiagatus: how hot is your hotspot?, September 23, 2022, 4:45 PM - 6:15 PM Aspergillus fumigatus is the leading invasive mold pathogens in humans. The first line of treatment for invasive A. fumigatus infections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af5d6bfe10b5ce3b9c80b68685aedb3c
https://doi.org/10.1093/mmy/myac072.s9.2d
https://doi.org/10.1093/mmy/myac072.s9.2d
Autor:
Hila Werner, Ammar Abou Kandil, Zohar Meir, Yehonathan Malis, Yona Shadkchan, Gal Masrati, Nir Ben-Tal, Koret Hirschberg, Nir Osherov
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3705
Volume 24
Issue 4
Pages: 3705
The opportunistic fungus Aspergillus fumigatus is the primary invasive mold pathogen in humans, and is responsible for an estimated 200,000 yearly deaths worldwide. Most fatalities occur in immunocompromised patients who lack the cellular and humoral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29cf06fb2f1011495b9c038a3f43350
https://doi.org/10.3390/ijms24043705
https://doi.org/10.3390/ijms24043705
Autor:
Ronen Ben-Ami, Nir Osherov, Yona Shadkchan, Wei Liu, Jennifer Scott, Jorge Amich, Zohar Meir, Mariana Handelman
Publikováno v:
Antimicrob Agents Chemother
Aspergillus fumigatus is the most common cause of invasive fungal mold infections in immunocompromised individuals. Current antifungal treatment relies heavily on the triazole antifungals which inhibit fungal Erg11/Cyp51 activity and subsequent ergos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8746a6d81231ca74e8d3405ab1bba7d4
https://europepmc.org/articles/PMC8448118/
https://europepmc.org/articles/PMC8448118/
Publikováno v:
Virulence
Virulence, Vol 9, Iss 1, Pp 1036-1049 (2018)
Virulence, Vol 9, Iss 1, Pp 1036-1049 (2018)
Background: Aspergillus fumigatus is the most prevalent airborne fungal pathogen, causing invasive fungal infections mainly in immunosuppressed individuals. Death rates from invasive aspergillosis remain high because of limited treatment options and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85b309575b61dfc5d59aa0628567a1a
https://doi.org/10.1080/21505594.2018.1482181
https://doi.org/10.1080/21505594.2018.1482181
Publikováno v:
Medical Mycology. 47:457-462
Combinations of caspofungin (CAS) with amphotericin-B (AMB), voriconazole (VRC), terbinafine (TRB) and tacrolimus (FK-506) were tested in vitro with 10 Fusarium isolates. MIC and minimal effective concentrations (MEC) were investigated in accord with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c208d5acf4875f32061d7005d59575
https://doi.org/10.1080/13693780802232910
https://doi.org/10.1080/13693780802232910
Autor:
Dodo Chikvashvili, Dimitrios P. Kontoyiannis, Nir Osherov, Yona Shadkchan, Gabriel Mircus, Dafna Ben-Yaakov, Nathaniel D. Albert
Publikováno v:
Antimicrobial agents and chemotherapy. 59(9)
Invasive mycotic infections have become more common during recent decades, posing an increasing threat to public health. However, despite the growing needs, treatments for invasive fungal infections remain unsatisfactory and are limited to a small nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4d2f94e33c14d7767fc6cc58a06d95
https://pubmed.ncbi.nlm.nih.gov/26149982
https://pubmed.ncbi.nlm.nih.gov/26149982
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:3279-3283
Caspofungin (CAS) inhibits fungal cell wall synthesis. Sulfamethoxazole (SMX) inhibits folate biosynthesis and is active in vitro against Aspergillus spp. We studied the activities of the combination of CAS and SMX against 31 Aspergillus isolates and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2234ee7b797b9ba568fd0f815b6fa7f8
https://doi.org/10.1128/aac.48.9.3279-3283.2004
https://doi.org/10.1128/aac.48.9.3279-3283.2004