Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yolandi Swart"'
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0264657 (2022)
Researchers would generally adjust for the possible confounding effect of population structure by considering global ancestry proportions or top principle components. Alternatively, researchers would conduct admixture mapping to increase the power to
Externí odkaz:
https://doaj.org/article/c2b16ef835f44b84869235d3dba1676f
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis, is a complex disease. The risk of developing active TB is in part determined by host genetic factors. Most genetic studies investigating TB susceptibility fail to replicate associatio
Externí odkaz:
https://doaj.org/article/71d866852968460da040c59b33991dda
Autor:
Bruno Maranda, Sébastien M. Labbé, Magali Lurquin, Pascal Brabant, Alexandre Fugère, Jean-François Larrivée, Djordje Grbic, Annie Leroux, Frédéric Leduc, Andres Finzi, Simon Gaudreau, Yolandi Swart, anon Investigators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::690a102e39441ffcc4edeeea0c11d559
https://doi.org/10.2139/ssrn.4436402
https://doi.org/10.2139/ssrn.4436402
Autor:
Yolandi Swart, Caitlin Uren, Clare Eckold, Jacqueline M Cliff, Stephanus T Malherbe, Katharina Ronacher, Vinod Kumar, Cisca Wijmenga, Hazel M Dockrell, Reinout van Crevel, Gerhard Walzl, Léanie Kleynhans, Marlo Möller
The validation of genome-wide association signals for tuberculosis (TB) susceptibility and the development of type 2 diabetes (T2D) across diverse populations remain problematic. The ancestry-specific variants (coding and non-coding) that contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b45c3c54a9ff8f6dab7f91618f9a72a9
https://doi.org/10.1101/2022.10.19.512814
https://doi.org/10.1101/2022.10.19.512814
Publikováno v:
Molecular Genetics and Genomics
Population substructure within human populations is globally evident and a well-known confounding factor in many genetic studies. In contrast, admixture mapping exploits population stratification to detect genotype–phenotype correlations in admixed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f617ec482f6b4f643c53a1c4175a899
https://doi.org/10.1007/s00438-020-01684-8
https://doi.org/10.1007/s00438-020-01684-8
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Frontiers in Genetics
Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis, is a complex disease. The risk of developing active TB is in part determined by host genetic factors. Most genetic studies investigating TB susceptibility fail to replicate associatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a457dc12e07499907fe2f684778f1f9d
https://www.frontiersin.org/articles/10.3389/fgene.2021.716558/full
https://www.frontiersin.org/articles/10.3389/fgene.2021.716558/full