Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yolande Rouiller"'
Autor:
Matthieu Stettler, Natacha Collet, Hervé Broly, Martin Jordan, Arnaud Périlleux, Yolande Rouiller
Publikováno v:
mAbs. 5:501-511
An innovative high-throughput medium development method based on media blending was successfully used to improve the performance of a Chinese hamster ovary fed-batch medium in shaking 96-deepwell plates. Starting from a proprietary chemically-defined
Autor:
Yolande Rouiller, Arnaud Périlleux, Hervé Broly, Marie-Noëlle Vesin, Milène Marsaut, Matthieu Stettler
Publikováno v:
Biotechnology Progress. 28:803-813
Glucocorticoids are known to modulate various cellular functions such as cell proliferation, metabolism, glycosylation, and secretion of many proteins. We tested the effect of hydrocortisone (HC) on cell growth, viability, metabolism, protein product
Autor:
Yolande, Rouiller, Beate, Kleuser, Emiliano, Toso, Wolf, Palinksy, Mara, Rossi, Paola, Rossatto, Davide, Barberio, Hervé, Broly
Publikováno v:
PDA journal of pharmaceutical science and technology. 69(4)
During the validation of an additional working cell bank derived from a validated master cell bank to support the commercial production continuum of a recombinant protein, we observed an unexpected chromosomal location of the gene of interest in some
Autor:
David Brühlmann, Martin Jordan, Hervé Broly, Jean-Marc Bielser, Yolande Rouiller, Matthieu Stettler
Publikováno v:
Biotechnology progress. 32(1)
The major challenge in the selection process of recombinant cell lines for the production of biologics is the choice, early in development, of a clonal cell line presenting a high productivity and optimal cell growth. Most importantly, the selected c
Autor:
Martin Jordan, Arnaud Périlleux, Yolande Rouiller, Marie-Noëlle Vesin, Hervé Broly, Matthieu Stettler
Publikováno v:
Biotechnology progress. 30(3)
A high-throughput DoE approach performed in a 96-deepwell plate system was used to explore the impact of media and feed components on main quality attributes of a monoclonal antibody. Six CHO-S derived clonal cell lines expressing the same monoclonal
Autor:
Alex Eon-Duval, Thomas Solacroup, Hervé Broly, Marco Barbafieri, Ralf Gleixner, Yolande Rouiller, Véronique Deparis
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 81(2)
The production bioreactor step of an Fc-Fusion protein manufacturing cell culture process was characterized following Quality by Design principles. Using scientific knowledge derived from the literature and process knowledge gathered during developme
Autor:
Rouiller, Yolande, Bielser, Jean‐Marc, Brühlmann, David, Jordan, Martin, Broly, Hervé, Stettler, Matthieu
Publikováno v:
Biotechnology Progress; Jan/Feb2016, Vol. 32 Issue 1, p160-170, 11p
Autor:
Brühlmann, David, Jordan, Martin, Hemberger, Jürgen, Sauer, Markus, Stettler, Matthieu, Broly, Hervé
Publikováno v:
Biotechnology Progress; May2015, Vol. 31 Issue 3, p615-629, 15p
Autor:
Rouiller, Yolande, Périlleux, Arnaud, Vesin, Marie‐Noëlle, Stettler, Matthieu, Jordan, Martin, Broly, Hervé
Publikováno v:
Biotechnology Progress; May2014, Vol. 30 Issue 3, p571-583, 13p
Autor:
Rouiller, Yolande, Périlleux, Arnaud, Marsaut, Milène, Stettler, Matthieu, Vesin, Marie-Noëlle, Broly, Hervé
Publikováno v:
Biotechnology Progress; May/Jun2012, Vol. 28 Issue 3, p803-813, 11p, 4 Charts, 9 Graphs