Výsledky vyhledávání - "Yolande Bastien"

Function of Histone Deacetylase 6 as a Cofactor of Nuclear Receptor Coregulator LCoR

Autor: Isabelle Fernandes, Mark Verway, Sylvie Mader, John H. White, Yolande Bastien, Liqun Tang, Ana Palijan, Véronique Bourdeau, Zhi Li, Xiang-Jiao Yang, Luz E. Tavera-Mendoza, Maria Kourelis

Publikováno v: Journal of Biological Chemistry. 284:30264-30274

Ligand-dependent corepressor LCoR was identified as a protein that interacts with the estrogen receptor alpha (ERalpha) ligand binding domain in a hormone-dependent manner. LCoR also interacts directly with histone deacetylase 3 (HDAC3) and HDAC6. No

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ea6108418d509c6bc30a043305de14
https://doi.org/10.1074/jbc.m109.045526

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Ligand-dependent Corepressor LCoR Is an Attenuator of Progesterone-regulated Gene Expression

Autor: Maria Kourelis, Luz E. Tavera-Mendoza, Aaron Sacheli, Yolande Bastien, John H. White, Sylvie Mader, Mark Verway, Isabelle Fernandes, Ana Palijan, Véronique Bourdeau

Publikováno v: Journal of Biological Chemistry. 284:30275-30287

Ligand-dependent corepressor LCoR interacts with the progesterone receptor (PR) and estrogen receptor ERalpha in the presence of hormone. LCoR contains tandem N-terminal PXDLS motifs that recruit C-terminal-binding protein (CtBP) corepressors as well

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5af9a95321a7735c38e7b741d17eb6
https://doi.org/10.1074/jbc.m109.051201

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Expression Profiling in Squamous Carcinoma Cells Reveals Pleiotropic Effects of Vitamin D3 Analog EB1089 Signaling on Cell Proliferation, Differentiation, and Immune System Regulation

Autor: Yolande Bastien, Eleftherios P. Diamandis, Georgia Sotiropoulou, Thomas J. Hudson, John H. White, Yoshihiko Nagai, Roberto Lin, Kevin Petrecca, Robert Sladek, Joanne Ho

Publikováno v: Molecular Endocrinology. 16:1243-1256

The active form of vitamin D3, 1alpha,25-dihydroxyvitamin D3 [1,25-(OH)2D3] is key mediator of calcium homeostasis and is a component of the complex homeostatic system of the skin. 1,25-(OH)2D3 regulates cellular differentiation and proliferation and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3388f30685ba4fd53af867861c34c612
https://doi.org/10.1210/mend.16.6.0874

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Dose-dependent agonist and antagonist effects of the platelet-activating factor analogue 1-palmitoyl-2-acetoyl-sn-glycero-3-phosphocholine on B lymphocytes

Autor: Bruce Mazer, Baruch Toledano, Mehrdad Saririan, Yolande Bastien

Publikováno v: Journal of Allergy and Clinical Immunology. 102:231-237

Background: Platelet activating-factor (PAF), an ether-linked phospholipid, is a potent activator of B lymphocyte cell lines. The related ester-linked phospholipid, 1-palmitoyl-2-acetoyl- sn -glycero-3-phosphocholine (PAGPC), is synthesized by tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3456cc256a56a2b8caae6edc8f09aa1
https://doi.org/10.1016/s0091-6749(98)70091-0

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Detection of the Human Platelet-Activating Factor Receptor mRNA in Human B Lymphocytes by Polymerase Chain Reaction on Reverse Transcripts (RT-PCR)

Autor: Bruce Mazer, Yolande Bastien

Publikováno v: Biochemical and Biophysical Research Communications. 202:1373-1379

The platelet activating factor receptor (hPAFR) is a GTP binding protein linked receptor of the rhodopsin family. The hPAFR gene maps to chromosome 1 and is characterized by the absence of introns in its coding region. Because PAF demonstrates unique

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f6c593a8b2640f0b808f6b24ca4d3c
https://doi.org/10.1006/bbrc.1994.2082

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Platelet-Activating Factor Antagonists Decrease Follicular Dendritic-Cell Stimulation of Human B Lymphocytes

Autor: Isaac Halickman, Qianli Zhuang, Baruch Toledano, Monty B Mazer, Yolande Bastien, Bruce Mazer

Publikováno v: Allergy, Asthma & Clinical Immunology, Vol 1, Iss 2, Pp 49-57 (2005)
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology

Both B-lymphoblastoid cell lines and tonsillar B lymphocytes express receptors for platelet-activating factor (PAF). In lymph node germinal centres, B lymphocytes interact with follicular dendritic cells (FDCs), which present antigen-containing immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2808c86d59074f6d7d318d024c1c9702
https://doi.org/10.1186/1710-1492-1-2-49

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Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms

Autor: Roberto Lin, Karen Nygard, Xiang-Jiao Yang, Frankie Eng, Yolande Bastien, Nicholas Bertos, Nadine Pelletier, Isabelle Fernandes, Olivier Cormier, John H. White, Han S. Lee, Sylvie Mader, Victor K. M. Han, Timothy Wai

Publikováno v: Molecular cell. 11(1)

LCoR (ligand-dependent corepressor) is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LXXLL motif. LCoR binding to estrogen receptor alpha depends in par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b383a6bb9d45c6ec03665828acc231f7
https://pubmed.ncbi.nlm.nih.gov/12535528

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Regulation of gene Expression by 1alpha,25-dihydroxyvitamin D3 and Its analog EB1089 under growth-inhibitory conditions in squamous carcinoma Cells

Autor: Alain Bestawros, John H. White, Danny Enepekides, Yolande Bastien, Naotake Akutsu, Martin J. Black, Roberto Lin

Publikováno v: Molecular endocrinology (Baltimore, Md.). 15(7)

Analogs of 1alpha,25-dihydroxyvitamin D(3) (1alpha, 25(OH)2D3) inhibit growth in vitro and in vivo of cells derived from a variety of tumors. Here, we examined the effects of 1alpha,25(OH)2D3 and its analog EB1089 on proliferation and target gene reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd4e7bd880c90191dda793b7a72afb9
https://pubmed.ncbi.nlm.nih.gov/11435613

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Action of low calcemic 1alpha,25-dihydroxyvitamin D3 analogue EB1089 in head and neck squamous cell carcinoma

Autor: Roberto Lin, Martin J. Black, Taiqui Wang, José Prudencio, John H. White, Naciba Benlimame, Moulay A. Alaoui-Jamali, Yolande Bastien, Naotake Akutsu

Publikováno v: Journal of the National Cancer Institute. 93(10)

BACKGROUND 1alpha,25-Dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] and its analogues inhibit growth of various types of cancer cells. Although the therapeutic potential of 1,25(OH)(2)D(3) is limited by its tendency to induce hypercalcemia, analogues such a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a804c8d39a57c404c5c88c95742435e2
https://pubmed.ncbi.nlm.nih.gov/11353784

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Activation via multiple signaling pathways induces down-regulation of platelet-activating factor receptors on human B lymphocytes

Autor: Bruce Mazer, Qianli Zhuang, Yolande Bastien

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 165(5)

Platelet-activating factor receptor (PAFR) has been identified in B cell lines and primary human B cells, but the regulation of PAFR during B cell activation has not been completely elucidated. In the present study, we have investigated the effects o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bfe1a699cbccdf853a0d8113eb56d6
https://pubmed.ncbi.nlm.nih.gov/10946267

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