Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yolanda Stypula-Cyrus"'
Autor:
Yolanda Stypula-Cyrus, Dhwanil Damania, Dhananjay P Kunte, Mart Dela Cruz, Hariharan Subramanian, Hemant K Roy, Vadim Backman
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64600 (2013)
Normal cell function is dependent on the proper maintenance of chromatin structure. Regulation of chromatin structure is controlled by histone modifications that directly influence chromatin architecture and genome function. Specifically, the histone
Externí odkaz:
https://doaj.org/article/96c0cd6b3f424692890b7f0cad08b12b
Autor:
Vadim Backman, Ashish K. Tiwari, Andrew J. Radosevich, Christopher R. Weber, Navneet Momi, Anuj Chhaparia, Hemant K. Roy, Bilal Latif, Audrey H. Calderwood, Yolanda Stypula-Cyrus, Ramesh K. Wali, Mart Dela Cruz, Luay M. Almassalha
Publikováno v:
Cancer Prevention Research. 9:844-854
Alterations in high order chromatin, with concomitant modulation in gene expression, are one of the earliest events in the development of colorectal cancer. Cohesins are a family of proteins that modulate high-order chromatin, although the role in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2863d41593c5d0a45bca35fc2fa48e2d
https://doi.org/10.1158/1940-6207.capr-16-0054
https://doi.org/10.1158/1940-6207.capr-16-0054
Autor:
Luay M. Almassalha, Biqin Dong, Ben E. Urban, Cheng Sun, The-Quyen Nguyen, Yolanda Stypula-Cyrus, Hao Zhang, Vadim Backman, John E. Chandler
Publikováno v:
Proceedings of the National Academy of Sciences. 113:9716-9721
Visualizing the nanoscale intracellular structures formed by nucleic acids, such as chromatin, in nonperturbed, structurally and dynamically complex cellular systems, will help expand our understanding of biological processes and open the next fronti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bdfcf4e1bec25d73ff8b44dac2b8f5
https://doi.org/10.1073/pnas.1602202113
https://doi.org/10.1073/pnas.1602202113
Publikováno v:
Biophysical Journal. 109(11):2218-2226
Chromatin organization has a fundamental impact on the whole spectrum of genomic functions. Quantitative characterization of the chromatin structure, particularly at submicron length scales where chromatin fractal globules are formed, is critical to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0333409f7706ebef58e409663cf15f5
Autor:
Luay M. Almassalha, Vadim Backman, Yolanda Stypula-Cyrus, Biqin Dong, Ben E. Urban, The-Quyen Nguyen, Hao Zhang, John E. Chandler, Cheng Sun
Publikováno v:
Single Molecule Spectroscopy and Superresolution Imaging X.
Imaging the nanoscale intracellular structures formed by nucleic acids, such as chromatin, in non-perturbed, structurally and dynamically complex cellular systems, will help improve our understanding of biological processes and open the next frontier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac6bc693b1b53a6294b05f381e9d486d
https://doi.org/10.1117/12.2254900
https://doi.org/10.1117/12.2254900
Autor:
Xiang Zhou, Luay M. Almassalha, Yolanda Stypula-Cyrus, Reiner Bleher, Vadim Backman, Eric W. Roth, Vinayak P. Dravid, Karl A. Hujsak, Igal Szleifer, Hariharan Subramanian, Yue Li, John E. Chandler
Publikováno v:
Experimental cell research. 358(2)
Chemical fixation is nearly indispensable in the biological sciences, especially in circumstances where cryo-fixation is not applicable. While universally employed for the preservation of cell organization, chemical fixatives often introduce artifact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c149fd67a8fa796f72e67da1021095be
https://pubmed.ncbi.nlm.nih.gov/28673821
https://pubmed.ncbi.nlm.nih.gov/28673821
Autor:
Igal Szleifer, Hemant K. Roy, Yolanda Stypula-Cyrus, Charles C White, Charles D. Maneval, John E. Chandler, Lusik Cherkezyan, M A Dela Cruz, Hariharan Subramanian, Hiroaki Matsuda, Vadim Backman, Ashish K. Tiwari, Luay M. Almassalha, Peder Thusgaard Ruhoff
Publikováno v:
Almassalha, L M, Tiwari, A, Ruhoff, P T, Stypula-Cyrus, Y, Cherkezyan, L, Matsuda, H, Dela Cruz, M A, Chandler, J E, White, C C, Maneval, C, Subramanian, H, Szleifer, I, Roy, H K & Backman, V 2017, ' The global relationship between chromatin physical topology, fractal structure, and gene expression ', Scientific Reports, vol. 7, pp. 41061 . https://doi.org/10.1038/srep41061
Scientific Reports
Scientific Reports
Most of what we know about gene transcription comes from the view of cells as molecular machines: focusing on the role of molecular modifications to the proteins carrying out transcriptional reactions at a loci-by-loci basis. This view ignores a crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c21d0222c0e1f9ba725049030381233
https://findresearcher.sdu.dk:8443/ws/files/125211374/srep41061.pdf
https://findresearcher.sdu.dk:8443/ws/files/125211374/srep41061.pdf
Autor:
Vadim Backman, Peder Thusgaard Ruhoff, Navdeep S. Chandel, Greta M. Bauer, Lusik Cherkezyan, Luay M. Almassalha, Yolanda Stypula-Cyrus, Igal Szleifer, Hariharan Subramanian, Hemant K. Roy, Scott Gladstein, Di Zhang, Samuel E. Weinberg, John E. Chandler
Publikováno v:
Almassalha, L M, Bauer, G M, Chandler, J E, Gladstein, S, Cherkezyan, L, Stypula-Cyrus, Y, Weinberg, S, Zhang, D, Thusgaard Ruhoff, P, Roy, H K, Subramanian, H, Chandel, N S, Szleifer, I & Backman, V 2016, ' Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy ', National Academy of Sciences. Proceedings, vol. 113, no. 42, pp. E6372-E6381 . https://doi.org/10.1073/pnas.1608198113
The organization of chromatin is a regulator of molecular processes including transcription, replication, and DNA repair. The structures within chromatin that regulate these processes span from the nucleosomal (10-nm) to the chromosomal (>200-nm) lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5532f063b6dba6f706f1fb05d39f00df
https://europepmc.org/articles/PMC5081614/
https://europepmc.org/articles/PMC5081614/
Autor:
Luay M. Almassalha, Hariharan Subramanian, Hemant K. Roy, Greta M. Bauer, Scott Gladstein, Yolanda Stypula-Cyrus, John E. Chandler, Lusik Cherkezyan, Di Zhang, Igal Szleifer, Samuel E. Weinberg, Peder Thusgaard Ruhoff, Navdeep S. Chandel, Vadim Backman
The organization of chromatin is a regulator of molecular processes including transcription, replication, and DNA repair. The structures within chromatin that regulate these processes span from the nucleosomal (10nm) to the chromosomal (>200nm) level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62473fff0f667380d8e22893fe783743
Autor:
Hariharan Subramanian, John E. Chandler, Luay M. Almassalha, Vadim Backman, Yolanda Stypula-Cyrus, Leah Bowen, Greta M. Bauer, Igal Szleifer
Publikováno v:
Journal of biophotonics. 10(3)
A new multimodal confocal microscope has been developed, which includes a parallel Partial Wave Spectroscopic (PWS) microscopy path. This combination of modalities allows molecular-specific sensing of nanoscale intracellular structure using fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b8b0eba29851f19a5a7e783f2725c6
https://pubmed.ncbi.nlm.nih.gov/27111884
https://pubmed.ncbi.nlm.nih.gov/27111884