From Chronodisruption to Sarcopenia: The Therapeutic Potential of Melatonin

Autor: José Fernández-Martínez, Yolanda Ramírez-Casas, Yang Yang, Paula Aranda-Martínez, Laura Martínez-Ruiz, Germaine Escames, Darío Acuña-Castroviejo

Publikováno v: Biomolecules, Vol 13, Iss 12, p 1779 (2023)

Sarcopenia is an age-related condition that involves a progressive decline in muscle mass and function, leading to increased risk of falls, frailty, and mortality. Although the exact mechanisms are not fully understood, aging-related processes like i

Externí odkaz: https://doaj.org/article/b01602375bba48f2920cc5ec80f12986

Age and Chronodisruption in Mouse Heart: Effect of the NLRP3 Inflammasome and Melatonin Therapy

Autor: Marisol Fernández-Ortiz, Ramy K. A. Sayed, Yolanda Román-Montoya, María Ángeles Rol de Lama, José Fernández-Martínez, Yolanda Ramírez-Casas, Javier Florido-Ruiz, Iryna Rusanova, Germaine Escames, Darío Acuña-Castroviejo

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
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International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6846

Age and age-dependent inflammation are two main risk factors for cardiovascular diseases. Aging can also affect clock gene-related impairments such as chronodisruption and has been linked to a decline in melatonin synthesis and aggravation of the NF-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332a697f10a0b52cc8dc9544e9e73d71
http://hdl.handle.net/10481/75989

ZEBRAFISH PARKINSONISM AFFECTS CLOCK GENES EXPRESSION, CAUSING CHRONODISRUPTION-RELATED LOSS OF LOCOMOTOR ACTIVITY, MELATONIN RHYTHM, AND MITOCHONDRIAL DYNAMICS SHIFT, WHICH ARE RESTORED BY MELATONIN TREATMENT

Autor: Paula Aranda Martinez, Jose Fernández Martínez, Yolanda Ramírez Casas, Ana Guerra-Librero, Germaine Escames Rosa, Darío Acuña Castroviejo

Publikováno v: IBRO Neuroscience Reports, Vol 15, Iss , Pp S360- (2023)

Externí odkaz: https://doaj.org/article/c03dd9d8f0d547efa2204bd4ba0d4aa3