Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yolanda Ponstein"'
Autor:
Manoe J. Janssen, Tom T.G. Nieskens, Tessa A.M. Steevels, Pedro Caetano-Pinto, Dirk den Braanker, Melissa Mulder, Yolanda Ponstein, Shaun Jones, Rosalinde Masereeuw, Cathaline den Besten, Martijn J. Wilmer
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 298-307 (2019)
Antisense oligonucleotide therapy has been reported to be associated with renal injury. Here, the mechanism of reversible proteinuria was investigated by combining clinical, pre-clinical, and in vitro data. Urine samples were obtained from Duchenne m
Externí odkaz:
https://doaj.org/article/b87e4abe3c8947bda573024c4f50791f
Autor:
Yolanda Ponstein, Luis A. Fernandez, Juan S. Danobeitia, Peter J. Chlebeck, Erzsebet Polyak, Jose R. Torrealba, Casi L. Blanton, Yücel Yankol, Megan L. Springer, Michael J. Eerhart, Jeremy A. Sullivan, Saverio Capuano, Jose A. Reyes, Jennifer Coonen, Myron A. Pozniak, Laura J. Zitur, Anthony M. D'Alessandro, Weixiong Zhong, Edwin Van Amersfoort, William J. Burlingham, Cees van Kooten
Publikováno v:
Transplantation
Transplantation, 106(1), 60-71. LIPPINCOTT WILLIAMS & WILKINS
Transplantation, 106(1), 60-71. LIPPINCOTT WILLIAMS & WILKINS
Background: Complement activation in kidney transplantation is implicated in the pathogenesis of delayed graft function (DGF). This study evaluated the therapeutic efficacy of high-dose recombinant human C1 esterase inhibitor (rhC1INH) to prevent DGF
Autor:
Stefano Fumagalli, Arianna Piotti, Yolanda Ponstein, Maria Grazia De Simoni, Marco Oggioni, Edwin Van Amersfoort, Domenico Mercurio, Marco Gobbi, Alessia Valente
Publikováno v:
Brain, behavior, and immunity. 93
C1 esterase inhibitor (C1INH) is known to exert its inhibitory effect by binding to several target proteases of the contact and complement systems. One of C1INH's targets comprise mannose-binding lectin (MBL), a critical player in post-stroke pathoph
Autor:
Tiffany Zens, Anthony M. D’Alessandro, Michael J. Eerhart, Peter J. Chlebeck, Jose A. Reyes, Saverio Capuano, Daniel Burguete, Yucel Yankol, Yolanda Ponstein, Luis A. Fernandez, Jose R. Torrealba, Jennifer Coonen, William J. Burlingham, Kevin Brunner, Laura J. Zitur, Edwin Van Amersfoort, Myron A. Pozniak, Jeremy A. Sullivan, Juan S. Danobeitia, Arjang Djamali, Ewa Jankowska-Gan, Cees van Kooten
Publikováno v:
American Journal of Transplantation, 20(6), 1513-1526. WILEY
Delayed graft function (DGF) in renal transplant is associated with reduced graft survival and increased immunogenicity. The complement-driven inflammatory response after brain death (BD) and posttransplant reperfusion injury play significant roles i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b7a7a020e6c0b5601705b12f0a6b72
https://hdl.handle.net/1887/3185005
https://hdl.handle.net/1887/3185005
Autor:
Jérémy Silvano, Victoria Derr, Tracy L. Gales, Shaun R. Maguire, Ian Francis, Michael Adams, Yolanda Ponstein-Simarro Doorten, Marshall S. Scicchitano, Kendall S. Frazier, Cathaline den Besten, David Mullins, Richard Haworth, James E. Ridings, Rosanna C. Mirabile, Bernard Palate, Jennie A. Woodfine, Cécile Sobry, Sjef J. de Kimpe
Publikováno v:
Toxicologic pathology. 42(5)
Chronic administration of drisapersen, a 2′-OMe phosphorothioate antisense oligonucleotide (AON) to mice and monkeys resulted in renal tubular accumulation, with secondary tubular degeneration. Glomerulopathy occurred in both species with species-s
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