Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yolanda Ohene"'
Autor:
Yolanda Ohene, William J. Harris, Elizabeth Powell, Nina W. Wycech, Katherine F. Smethers, Samo Lasič, Kieron South, Graham Coutts, Andrew Sharp, Catherine B. Lawrence, Hervé Boutin, Geoff J. M. Parker, Laura M. Parkes, Ben R. Dickie
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Blood–brain barrier (BBB) dysfunction occurs in many brain diseases, and there is increasing evidence to suggest that it is an early process in dementia which may be exacerbated by peripheral infection. Filter-exchange imaging (FEXI) is an
Externí odkaz:
https://doaj.org/article/993f91b80b9647f1af20428f0e2b0cb2
Autor:
Charith Perera, Daniele Tolomeo, Rebecca R. Baker, Yolanda Ohene, Alla Korsak, Mark F. Lythgoe, David L. Thomas, Jack A. Wells
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Chronic hypertension is a major risk factor for the development of neurodegenerative disease, yet the etiology of hypertension-driven neurodegeneration remains poorly understood. Forming a unique interface between the systemic circulation and the bra
Externí odkaz:
https://doaj.org/article/a9cfb96988374a9fa538e5809e844fa7
Autor:
Ian F Harrison, Bernard Siow, Aisha B Akilo, Phoebe G Evans, Ozama Ismail, Yolanda Ohene, Payam Nahavandi, David L Thomas, Mark F Lythgoe, Jack A Wells
Publikováno v:
eLife, Vol 7 (2018)
The glymphatics system describes a CSF-mediated clearance pathway for the removal of potentially harmful molecules, such as amyloid beta, from the brain. As such, its components may represent new therapeutic targets to alleviate aberrant protein accu
Externí odkaz:
https://doaj.org/article/ac2ca34016804c4aa72b5387b52ac633
Autor:
Elizabeth Powell, Yolanda Ohene, Marco Battiston, Ben R. Dickie, Laura M. Parkes, Geoff J. M. Parker
Publikováno v:
Powell, E, Ohene, Y, Battiston, M, Dickie, B R, Parkes, L M & Parker, G J M 2023, ' Blood-brain barrier water exchange measurements using FEXI : Impact of modeling paradigm and relaxation time effects ', Magnetic Resonance in Medicine, vol. 90, no. 1, pp. 34-50 . https://doi.org/10.1002/mrm.29616
Purpose: To evaluate potential modeling paradigms and the impact of relaxation time effects on human blood-brain barrier (BBB) water exchange measurements using FEXI (BBB-FEXI), and to quantify the accuracy, precision, and repeatability of BBB-FEXI e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3006568994026de6a544ef07929795
http://www.scopus.com/inward/record.url?scp=85150489515&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85150489515&partnerID=8YFLogxK
A technique for quantifying regional blood-brain barrier (BBB) water exchange rates using contrast-enhanced arterial spin labelling (CE-ASL) is presented and evaluated in simulations and in vivo. The two-compartment ASL model describes the water exch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a50b5292e0f5538538c0b2896a1ef3f4
https://doi.org/10.1101/2023.02.16.528529
https://doi.org/10.1101/2023.02.16.528529
Autor:
Jessica Wade, Isabel M. Rabey, Amy Smith, Sophie A. Martin, Matthew Okenyi, Yolanda Ohene, Mark D. Richards
Publikováno v:
Nature Reviews Materials. 7:927-928
Autor:
Phoebe G Evans, Jack A. Wells, David L. Thomas, Mark F. Lythgoe, Yolanda Ohene, Ian F. Harrison
Publikováno v:
Magnetic Resonance in Medicine
Purpose A fundamental goal in the drive to understand and find better treatments for dementia is the identification of the factors that render the aging brain vulnerable to neurodegenerative disease. Recent evidence indicates the integrity of the blo
Autor:
Ian F. Harrison, Phoebe G Evans, Enrique Miranda, A. Alves, Payam Nahavandi, David L. Thomas, Yolanda Ohene, Ozama Ismail, Magdalena Sokolska, Mark F. Lythgoe, Jack A. Wells
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
The blood–cerebrospinal fluid barrier (BCSFB) is a highly dynamic transport interface that serves brain homeostasis. To date, however, understanding of its role in brain development and pathology has been hindered by the absence of a non-invasive t
Autor:
Yolanda, Ohene, Ian F, Harrison, Payam, Nahavandi, Ozama, Ismail, Eleanor V, Bird, Ole P, Ottersen, Erlend A, Nagelhus, David L, Thomas, Mark F, Lythgoe, Jack A, Wells
Publikováno v:
Neuroimage
There is currently a lack of non-invasive tools to assess water transport in healthy and pathological brain tissue. Aquaporin-4 (AQP4) water channels are central to many water transport mechanisms, and emerging evidence also suggests that AQP4 plays
Autor:
Payam Nahavandi, Bernard Siow, Yolanda Ohene, Mark F. Lythgoe, Ozama Ismail, Phoebe G Evans, Jack A. Wells, Aisha B Akilo, David L. Thomas, Ian F. Harrison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8e44b337d7234a50bdbb146a48bc998
https://doi.org/10.7554/elife.34028.016
https://doi.org/10.7554/elife.34028.016