Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Yolanda Colino Sanguino"'
Autor:
Yolanda Colino-Sanguino, Laura Rodriguez de la Fuente, Brian Gloss, Andrew M.K. Law, Kristina Handler, Marina Pajic, Robert Salomon, David Gallego-Ortega, Fatima Valdes-Mora
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37185- (2024)
Single-cell transcriptomics has emerged as the preferred tool to define cell identity through the analysis of gene expression signatures. However, there are limited studies that have comprehensively compared the performance of different scRNAseq syst
Externí odkaz:
https://doaj.org/article/d3384de68ec04f0ba843ae1f7fd84e1d
Autor:
Andrew M. K. Law, Jiamin Chen, Yolanda Colino‐Sanguino, Laura Rodriguez de la Fuente, Guocheng Fang, Susan M. Grimes, Hongxu Lu, Robert J. Huang, Sarah T. Boyle, Jeron Venhuizen, Lesley Castillo, Javad Tavakoli, Joanna N. Skhinas, Ewan K. A. Millar, Julia Beretov, Fernando J. Rossello, Joanne L. Tipper, Christopher J. Ormandy, Michael S. Samuel, Thomas R. Cox, Luciano Martelotto, Dayong Jin, Fatima Valdes‐Mora, Hanlee P. Ji, David Gallego‐Ortega
Publikováno v:
Advanced Science, Vol 9, Iss 21, Pp n/a-n/a (2022)
Abstract To fully investigate cellular responses to stimuli and perturbations within tissues, it is essential to replicate the complex molecular interactions within the local microenvironment of cellular niches. Here, the authors introduce Alginate
Externí odkaz:
https://doaj.org/article/7c01605cf8c442bb9c5423b06b6545f3
Autor:
Yolanda Colino-Sanguino, Evan M. Cornett, David Moulder, Grady C. Smith, Joel Hrit, Eric Cordeiro-Spinetti, Robert M. Vaughan, Krzysztof Krajewski, Scott B. Rothbart, Susan J. Clark, Fátima Valdés-Mora
Publikováno v:
iScience, Vol 21, Iss , Pp 773-788 (2019)
Summary: Acetylation of the histone variant H2A.Z (H2A.Zac) occurs at active regulatory regions associated with gene expression. Although the Tip60 complex is proposed to acetylate H2A.Z, functional studies suggest additional enzymes are involved. He
Externí odkaz:
https://doaj.org/article/f6cdb89156f743b9b9d7ef0eed864668
Autor:
Evangeline R. Jackson, Ryan J. Duchatel, Dilana E. Staudt, Mika L. Persson, Abdul Mannan, Sridevi Yadavilli, Sarah Parackal, Shaye Game, Wai Chin Chong, W. Samantha N. Jayasekara, Marion Le Grand, Padraic S. Kearney, Alicia M. Douglas, Izac J. Findlay, Zacary P. Germon, Holly P. McEwen, Tyrone S. Beitaki, Adjanie Patabendige, David A. Skerrett-Byrne, Brett Nixon, Nathan D. Smith, Bryan Day, Neevika Manoharan, Sumanth Nagabushan, Jordan R. Hansford, Dinisha Govender, Geoff B. McCowage, Ron Firestein, Meegan Howlett, Raelene Endersby, Nicholas G. Gottardo, Frank Alvaro, Sebastian M. Waszak, Martin R. Larsen, Yolanda Colino-Sanguino, Fatima Valdes-Mora, Andria Rakotomalala, Samuel Meignan, Eddy Pasquier, Nicolas André, Esther Hulleman, David D. Eisenstat, Nicholas A. Vitanza, Javad Nazarian, Carl Koschmann, Sabine Mueller, Jason E. Cain, Matthew D. Dun
Publikováno v:
Cancer Research. :OF1-OF17
Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), are the most lethal of childhood cancers. Palliative radiotherapy is the only established treatment, with median patient survival of 9 to 11 months. ONC201 is a DRD2 a
Autor:
Fátima Valdés-Mora, Robert Salomon, Brian Stewart Gloss, Andrew Man Kit Law, Jeron Venhuizen, Lesley Castillo, Kendelle Joan Murphy, Astrid Magenau, Michael Papanicolaou, Laura Rodriguez de la Fuente, Daniel Lee Roden, Yolanda Colino-Sanguino, Zoya Kikhtyak, Nona Farbehi, James Ronald William Conway, Neblina Sikta, Samantha Richelle Oakes, Thomas Robert Cox, Seán Ignatius O’Donoghue, Paul Timpson, Christopher John Ormandy, David Gallego-Ortega
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108945- (2021)
Summary: Basal breast cancer is associated with younger age, early relapse, and a high mortality rate. Here, we use unbiased droplet-based single-cell RNA sequencing (RNA-seq) to elucidate the cellular basis of tumor progression during the specificat
Externí odkaz:
https://doaj.org/article/ea3e8ab5138c4f7d98816a22a8d74a0d
Autor:
Ayesha Ali, Shafiq M. Syed, M. Fairuz B. Jamaluddin, Yolanda Colino-Sanguino, David Gallego-Ortega, Pradeep S. Tanwar
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1463-1477.e7 (2020)
Summary: The intact vaginal epithelium is essential for women’s reproductive health and provides protection against HIV and sexually transmitted infections. How this epithelium maintains itself remains poorly understood. Here, we used single-cell R
Externí odkaz:
https://doaj.org/article/4b3a2d42e98449e580d3f9f9883464ae
Autor:
Fátima Valdés-Mora, Cathryn M. Gould, Yolanda Colino-Sanguino, Wenjia Qu, Jenny Z. Song, Kylie M. Taylor, Fabian A. Buske, Aaron L. Statham, Shalima S. Nair, Nicola J. Armstrong, James G. Kench, Kenneth M. L. Lee, Lisa G. Horvath, Minru Qiu, Alexei Ilinykh, Nicole S. Yeo-Teh, David Gallego-Ortega, Clare Stirzaker, Susan J. Clark
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Acetylation of the histone variant H2A.Z at gene promoters is associated with oncogene activation; however, it is unclear if such modification has a role in regulating the function of enhancers. Here the authors show that acetylated H2A.Z is redistri
Externí odkaz:
https://doaj.org/article/d2ff8d2d6d19424694b455f94d09d58c
Autor:
Matthew D. Dun, Jason E. Cain, Sabine Mueller, Carl Koschmann, Javad Nazarian, Nicholas A. Vitanza, David D. Eisenstat, Esther Hulleman, Nicolas André, Eddy Pasquier, Samuel Meignan, Andria Rakotomalala, Fatima Valdes-Mora, Yolanda Colino-Sanguino, Martin R. Larsen, Sebastian M. Waszak, Frank Alvaro, Nicholas G. Gottardo, Raelene Endersby, Meegan Howlett, Ron Firestein, Geoff B. McCowage, Dinisha Govender, Jordan R. Hansford, Sumanth Nagabushan, Neevika Manoharan, Bryan Day, Nathan D. Smith, Brett Nixon, David A. Skerrett-Byrne, Adjanie Patabendige, Tyrone S. Beitaki, Holly P. McEwen, Zacary P. Germon, Izac J. Findlay, Alicia M. Douglas, Padraic S. Kearney, Marion Le Grand, W. Samantha N. Jayasekara, Wai Chin Chong, Shaye Game, Sarah Parackal, Sridevi Yadavilli, Abdul Mannan, Mika L. Persson, Dilana E. Staudt, Ryan J. Duchatel, Evangeline R. Jackson
All Supplementary Figures and their captions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9e68dc3c6f26e99f51f1fbaa7e5b3a
https://doi.org/10.1158/0008-5472.22892044
https://doi.org/10.1158/0008-5472.22892044
Autor:
Matthew D. Dun, Jason E. Cain, Sabine Mueller, Carl Koschmann, Javad Nazarian, Nicholas A. Vitanza, David D. Eisenstat, Esther Hulleman, Nicolas André, Eddy Pasquier, Samuel Meignan, Andria Rakotomalala, Fatima Valdes-Mora, Yolanda Colino-Sanguino, Martin R. Larsen, Sebastian M. Waszak, Frank Alvaro, Nicholas G. Gottardo, Raelene Endersby, Meegan Howlett, Ron Firestein, Geoff B. McCowage, Dinisha Govender, Jordan R. Hansford, Sumanth Nagabushan, Neevika Manoharan, Bryan Day, Nathan D. Smith, Brett Nixon, David A. Skerrett-Byrne, Adjanie Patabendige, Tyrone S. Beitaki, Holly P. McEwen, Zacary P. Germon, Izac J. Findlay, Alicia M. Douglas, Padraic S. Kearney, Marion Le Grand, W. Samantha N. Jayasekara, Wai Chin Chong, Shaye Game, Sarah Parackal, Sridevi Yadavilli, Abdul Mannan, Mika L. Persson, Dilana E. Staudt, Ryan J. Duchatel, Evangeline R. Jackson
Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), are the most lethal of childhood cancers. Palliative radiotherapy is the only established treatment, with median patient survival of 9 to 11 months. ONC201 is a DRD2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2ec734b3b0e0b8ca6a532d4cfa2040
https://doi.org/10.1158/0008-5472.c.6651055.v1
https://doi.org/10.1158/0008-5472.c.6651055.v1
Autor:
Yolanda Colino-Sanguino, Laura Rodriguez de la Fuente, Brian Gloss, Andrew M. K. Law, Kristina Handler, Marina Pajic, Robert Salomon, David Gallego-Ortega, Fatima Valdes-Mora
Single-cell transcriptomics has emerged as the preferred tool to define cell identity through the analysis of gene expression signatures. However, there are limited studies that have comprehensively compared the performance of different scRNAseq syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea0f7cd54c6fe7433a22db3329d1bd14
https://doi.org/10.1101/2023.04.04.535585
https://doi.org/10.1101/2023.04.04.535585