Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yoland eSmith"'
Publikováno v:
Frontiers in Neuroanatomy, Vol 9 (2015)
The striatum and the subthalamic nucleus are the main entry doors for extrinsic inputs to reach the basal ganglia circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei. There is functional
Externí odkaz:
https://doaj.org/article/218656395a3d40349505f033b35ef6fc
Autor:
Yoland eSmith, Adriana eGalvan, Tommas J Ellender, Natalie eDoig, Rosa M Villalba, Icnelia Huerta Ocampo, Thomas eWichman, Paul eBolam
Publikováno v:
Frontiers in Systems Neuroscience, Vol 8 (2014)
Because of our limited knowledge of the functional role of the thalamostriatal system, this massive network is often ignored in models of the pathophysiology of brain disorders of basal ganglia origin, such as Parkinson’s disease. However, over the
Externí odkaz:
https://doaj.org/article/20daba6ae09841d5bd76f4ef21c4e27b
Autor:
Rosa M Villalba, Yoland eSmith
Publikováno v:
Frontiers in Systems Neuroscience, Vol 5 (2011)
Striatal dopamine denervation is the pathological hallmark of Parkinson’s disease (PD). Another major pathological change described in animal models and PD patients is a significant reduction in the density of dendritic spines on medium spiny stria
Externí odkaz:
https://doaj.org/article/f1b816ad0eab4a25a796eef95e5b8b67
Autor:
Abraham eMathai, Yoland eSmith
Publikováno v:
Frontiers in Systems Neuroscience, Vol 5 (2011)
The basal ganglia receive cortical inputs through two main stations – the striatum and the subthalamic nucleus (STN). The information flowing along the corticostriatal system is transmitted to the basal ganglia circuitry via the direct and indirect
Externí odkaz:
https://doaj.org/article/c68b6e8d8dc1470a8f3107d561225e36
Publikováno v:
Frontiers in Systems Neuroscience, Vol 5 (2011)
GABA-transporter type 1 and 3 (GAT-1 and GAT-3, respectively) are the two main subtypes of GATs responsible for the regulation of extracellular GABA levels in the central nervous system. These transporters are widely expressed in neuronal (mainly GAT
Externí odkaz:
https://doaj.org/article/d46267771d0d45168059cdd90cffd025
Autor:
Rosa M Villalba, Yoland eSmith
Publikováno v:
Frontiers in Neuroanatomy, Vol 4 (2010)
Striatal dopamine (DA) denervation results in a significant loss of dendritic spines on medium spiny projection neurons in Parkinson’s disease (PD). In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated parkinsonian monkeys, spines contact
Externí odkaz:
https://doaj.org/article/a5eff7ecf16f49598e2eef2bc91ebf13