Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Yoko YAMADA"'
Autor:
Yu Yamazaki, Kaoruko Kikuchi, Yoko Yamada, Sakurako Neo, Suguru Nitta, Hirotaka Igarashi, Akihide Kamiya, Masaharu Hisasue
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 1078-1086 (2024)
Introduction: Exploring techniques for differentiating and culturing canine hepatocytes serves as a means to establish systems for liver transplantation and drug metabolism testing. However, establishing consistent methods for culturing stable hepato
Externí odkaz:
https://doaj.org/article/9261f8ef789b4bda9fac6af1dd8dc256
Autor:
Makoto Endo, Tomoko Kataoka, Toshifumi Fujiwara, Satoshi Tsukushi, Masanobu Takahashi, Eisuke Kobayashi, Yoko Yamada, Takaaki Tanaka, Yutaka Nezu, Hiroaki Hiraga, Junji Wasa, Akihito Nagano, Kenji Nakano, Robert Nakayama, Tetsuya Hamada, Masanori Kawano, Tomoaki Torigoe, Akio Sakamoto, Kunihiro Asanuma, Takeshi Morii, Ryunosuke Machida, Yuta Sekino, Haruhiko Fukuda, Yoshinao Oda, Toshifumi Ozaki, Kazuhiro Tanaka
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Soft tissue sarcomas (STS) are a rare type of malignancy comprising a variety of histological diagnoses. Chemotherapy constitutes the standard treatment for advanced STS. Doxorubicin-based regimens, which include the administratio
Externí odkaz:
https://doaj.org/article/fbc2c36541c844a2894c17228bd7e226
Autor:
Akito Ichikawa, Sakurako Neo, Ryouhei Nukui, Yoko Yamada, Suguru Nitta, Hidetoshi Iwaki, Yusuke Yanagi, Koichi Nakayama, Shoichi Sato, Satoko Tateishi, Masaharu Hisasue
Publikováno v:
Regenerative Therapy, Vol 19, Iss , Pp 1-8 (2022)
Introduction: Differentiation of hepatocytes and culture methods have been investigated in dogs as a tool to establish liver transplant and drug metabolism examination systems. However, mass culture techniques for canine hepatocytes (cHep) have not b
Externí odkaz:
https://doaj.org/article/66f965b67875475788eca93f61df0cbc
Autor:
Taro Ayabe, Masaharu Hisasue, Yoko Yamada, Suguru Nitta, Kaoruko Kikuchi, Sakurako Neo, Yuki Matsumoto, Ryo Horie, Kosuke Kawamoto
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Haematopoietic stem and progenitor cells (HSPCs) are used for transplantation to reconstruct the haematopoietic pathways in humans receiving severe chemotherapy. However, the characteristics of canine HSPCs, such as specific surface antigens and gene
Externí odkaz:
https://doaj.org/article/baf6043620054873999f485b0e2eb094
Autor:
Suguru Nitta, Masaharu Hisasue, Yu Horiguchi, Yoko Yamada, Kaoruko Kikuchi, Takeaki Kubo, Hirotaka Igarashi, Sakurako Neo
Publikováno v:
Regenerative Therapy, Vol 15, Iss , Pp 210-215 (2020)
Introduction: Primary cultured hepatocytes are an important model for early safety evaluations of newly developed drugs. Many factors, however, hinder the wider applications of this technology, especially the difficulty to maintain these cells in lon
Externí odkaz:
https://doaj.org/article/1c2338f18ac54705a158e8abe10aa42b
Autor:
Suguru Nitta, Yuto Kusakari, Yoko Yamada, Takeaki Kubo, Sakurako Neo, Hirotaka Igarashi, Masaharu Hisasue
Publikováno v:
Regenerative Therapy, Vol 14, Iss , Pp 165-176 (2020)
Introduction: Hepatocytes, which account for the majority of liver tissue, are derived from the endoderm and become hepatocytes via differentiation of hepatic progenitor cells. Induced hepatocyte-like (iHep) cells and artificial liver tissues are exp
Externí odkaz:
https://doaj.org/article/600a56e124cc4a09a910e098f3825cdc
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The 1-phosphatidylinositol-3-phosphate 5-kinase PIKfyve generates PtdIns3,5P2 on late phagolysosomes, which by recruiting the scission protein Atg18, results in their fragmentation in the normal course of endosome processing. Loss of PIKfyve function
Externí odkaz:
https://doaj.org/article/14c64f188c034a2d9b7965b525b948b4
Autor:
Gillian Forbes, Zhi-hui Chen, Koryu Kin, Hajara M. Lawal, Christina Schilde, Yoko Yamada, Pauline Schaap
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Dictyostelid social amoebas self-organize into fruiting bodies, consisting of spores and up to four supporting cell types in the phenotypically most complex taxon group 4. High quality genomes and stage- and cell-type specific tra
Externí odkaz:
https://doaj.org/article/286f83bee6be4ca6ac87028565a9c459
Autor:
Yoko Yamada, Shinji Watanabe, Keinosuke Okamoto, Sakae Arimoto, Eizo Takahashi, Kazuo Negishi, Tomoe Negishi
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-10 (2019)
Abstract Background Chloroethylnitrosourea (CENU) derivatives, such as nimustine (ACNU) and carmustine (BCNU), are employed in brain tumor chemotherapy due to their ability to cross the blood-brain barrier. They are thought to suppress tumor developm
Externí odkaz:
https://doaj.org/article/18c911c92240440f99643dc437b38246
Autor:
Yusuke Adachi, Takekuni Hayashi, Takeshi Mitsuhashi, Kenichi Sakakura, Yoko Yamada, Yuko Wada, Minoru Horie, Shin-ichi Momomura, Hideo Fujita
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-4 (2019)
Abstract Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited myocardial disease characterized by fibrofatty replacement and ventricular arrhythmias. ARVC is believed to be a disease of the young, with most cases being di
Externí odkaz:
https://doaj.org/article/17f83452e5134b7dbfe95d5c64d0447e