Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Yoko Y. Toyoshima"'
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183672 (2017)
Dynactin is a dynein-regulating protein that increases the processivity of dynein movement on microtubules. Recent studies have shown that a tripartite complex of dynein-dynactin-Bicaudal D2 is essential for highly processive movement. To elucidate t
Externí odkaz:
https://doaj.org/article/8baa2d41e23f4b3c83c0bf334cde6db0
Autor:
Takashi Sakurai, Tomone Hata, Tsutomu Fujimura, Takuya Kobayashi, Saiko Kazuno, Yoko Y. Toyoshima, Keitaro Shibata, Takashi Murayama, Kei Saito
Publikováno v:
Molecular Biology of the Cell
Dynactin is a principal regulator of the minus-end directed microtubule motor dynein. The sidearm of dynactin is essential for binding to microtubules and regulation of dynein activity. Although our understanding of the structure of the dynactin back
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832b6217f4abd9d840687247fa5a8237
https://doi.org/10.1091/mbc.e20-01-0031
https://doi.org/10.1091/mbc.e20-01-0031
Autor:
Keitaro Shibata, Michi Miura, Yuta Watanabe, Kei Saito, Atsuko Nishimura, Ken'ya Furuta, Yoko Y Toyoshima
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42990 (2012)
Cytoplasmic dynein and kinesin are two-headed microtubule motor proteins that move in opposite directions on microtubules. It is known that kinesin steps by a 'hand-over-hand' mechanism, but it is unclear by which mechanism dynein steps. Because dyne
Externí odkaz:
https://doaj.org/article/3897024a66f24558bfdf1de381e27b14
Autor:
Mitsuhiro Sugawa, Yoko Y. Toyoshima, Kei Saito, Keitaro Shibata, Fumihiko Fujii, Junichiro Yajima, Shin Yamaguchi, Tomoko Masaike, Nagisa Mikami, Takayuki Nishizaka
Publikováno v:
Biochemical and Biophysical Research Communications. 504:709-714
Single-molecule fluorescence polarization technique has been utilized to detect structural changes in biomolecules and intermolecular interactions. Here we developed a single-molecule fluorescence polarization measurement system, named circular orien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c060c6e648ad76a7e853c4508b9f1391
https://doi.org/10.1016/j.bbrc.2018.08.178
https://doi.org/10.1016/j.bbrc.2018.08.178
Autor:
Takashi Ishikawa, Takashi Murayama, Takuya Kobayashi, Muneyoshi Ichikawa, Yoko Y. Toyoshima, Hitoshi Sakakibara, Yuta Watanabe, Kei Saito
Publikováno v:
Handbook of Dynein ISBN: 9780429021312
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dd65e120e0f517586187f7ce329e5c7
https://doi.org/10.1201/9780429021312-4
https://doi.org/10.1201/9780429021312-4
Autor:
Keitaro Shibata, Takuya Kobayashi, Saiko Kazuno, Takashi Murayama, Keita Saito, Takashi Sakurai, Yoko Y. Toyoshima, Tsutomu Fujimura, Tomonori Hata
Dynactin is a principal regulator of the minus-end directed microtubule motor dynein. The sidearm of dynactin is essential for binding to microtubules and regulation of dynein activity. Although our understanding of the structure of the dynactin back
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192dbb4080a438cf67b31accfe0de0c2
https://doi.org/10.1101/459040
https://doi.org/10.1101/459040
Autor:
Yoko Y. Toyoshima, Mitsuhiro Sugawa, Kyohei Matsuda, Takuya Kobayashi, Yurika Koiso, Junichiro Yajima
The dynamic cytoskeletal network is responsible for cell shape changes and cell division. The actin-based motor protein myosin II drives the remodeling of a highly disordered actin-based network and enables the network to perform mechanical work such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d56fd788bcb5554451c2a533deed99
https://doi.org/10.1101/332684
https://doi.org/10.1101/332684
Publikováno v:
Seibutsu Butsuri. 55:127-132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be7db0264025cec54e8fb439c8728bd3
https://doi.org/10.2142/biophys.55.127
https://doi.org/10.2142/biophys.55.127
Autor:
Yasuharu Kushida, Haruaki Yanagisawa, Kentaro Nakano, Yoko Y. Toyoshima, Muneyoshi Ichikawa, Shin Yamaguchi, Kei Saito, Toshiki Yagi, Ritsu Kamiya, Junichiro Yajima, Osamu Numata
Publikováno v:
Molecular Biology of the Cell
Dynein light chain 1 (LC1) of the outer arm dynein (OAD) complex associates with the microtubule-binding domain (MTBD) of γ heavy chain inside the complex. LC1 is considered to regulate the OAD activity and ciliary/flagellar motion by modulating γ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019bee8a7f88e14382e596bec0d6dd7e
http://europepmc.org/articles/PMC4642857
http://europepmc.org/articles/PMC4642857
Autor:
Hiroaki Kojima, Ken'ya Furuta, Yoko Y. Toyoshima, Muneyoshi Ichikawa, Kei Saito, Takayuki Torisawa, Akane Furuta, Kazuhiro Oiwa
Publikováno v:
Nature Cell Biology. 16:1118-1124
Cytoplasmic dynein is a two-headed microtubule-based motor responsible for diverse intracellular movements, including minus-end-directed transport of organelles. The motility of cargo transporters is regulated according to the presence or absence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f732657e733bf926a879ad094b712299
https://doi.org/10.1038/ncb3048
https://doi.org/10.1038/ncb3048