Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yoko Takiuchi"'
Autor:
Yoko Takiuchi, Masayuki Kobayashi, Kohei Tada, Fumie Iwai, Maki Sakurada, Shigeki Hirabayashi, Kayoko Nagata, Kotaro Shirakawa, Keisuke Shindo, Jun-ichirou Yasunaga, Yasuhiro Murakawa, Vinodh Rajapakse, Yves Pommier, Masao Matsuoka, Akifumi Takaori-Kondo
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell leukemia virus type 1 (HTLV-1). We recently reported that abacavir, an anti-HIV-1 drug, potently and selectively kills ATL cells. This effect was attribute
Externí odkaz:
https://doaj.org/article/4ce52dd39fc841c4b3f83bf6d24a6459
Autor:
Takashi Sakamoto, Masayuki Kobayashi, Kohei Tada, Masanobu Shinohara, Katsuhiro Io, Kayoko Nagata, Fumie Iwai, Yoko Takiuchi, Yasuyuki Arai, Kouhei Yamashita, Keisuke Shindo, Norimitsu Kadowaki, Yoshio Koyanagi, Akifumi Takaori-Kondo
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85762 (2014)
The transcription factor NF-κB plays a key regulatory role in lymphocyte activation and generation of immune response. Stimulation of T cell receptor (TCR) induces phosphorylation of CARMA1 by PKCθ, resulting in formation of CARMA1-Bcl10-MALT1 (CBM
Externí odkaz:
https://doaj.org/article/737bb50d47ee4538937a727a10772ce3
Autor:
Maki Sakurada-Aono, Takashi Sakamoto, Masayuki Kobayashi, Yoko Takiuchi, Fumie Iwai, Kohei Tada, Hiroyuki Sasanuma, Shigeki Hirabayashi, Yasuhiro Murakawa, Kotaro Shirakawa, Chihiro Sakamoto, Keisuke Shindo, Jun-ichirou Yasunaga, Masao Matsuoka, Yves Pommier, Shunichi Takeda, Akifumi Takaori-Kondo
Publikováno v:
Biochemical and Biophysical Research Communications. 657:43-49
Autor:
Seishi Ogawa, Toshiyuki Kitano, Shojiro Inano, Kensuke Fujiwara, Junya Kanda, Mizuki Watanabe, Sho Shibata, Naoto Kawasaki, Sumie Tabata, Akiko Fukunaga, Akifumi Takaori-Kondo, Hiroo Ueno, Yasuhito Nannya, Yoko Takiuchi, Yoshio Okamoto
Publikováno v:
International Journal of Hematology. 115:428-434
Shwachman-Diamond syndrome (SDS) is an autosomal recessive inherited disorder characterized by bone marrow failure, exocrine pancreatic dysfunction, and skeletal abnormalities. SDS is typically caused by a pathogenic mutation in the Shwachman-Bodian-
Autor:
Sho Shibata, Yoko Takiuchi, Yoshio Okamoto, Akiko Fukunaga, Toshiyuki Kitano, Sumie Tabata, Naoto Kawasaki, Hajime Morita, Shojiro Inano, Tomomi Endo
Publikováno v:
Internal Medicine
TAFRO syndrome and POEMS syndrome are lymphoproliferative disorders with elevated interleukin-6 and vascular endothelial growth factor (VEGF) levels; however, their underlying pathogenic mechanisms remain unclear. Similarities have been reported in t
Autor:
Sho Shibata, Akiko Fukunaga, Toshiyuki Kitano, Yoko Takiuchi, Yoshio Okamoto, Sumie Tabata, Shojiro Inano, Kazuyo Yamamoto
Publikováno v:
Journal of Clinical and Experimental Hematopathology : JCEH
Methotrexate, hydrocortisone, vincristine, sobuzoxane, and etoposide (MTX-HOPE) chemotherapy was originally reported in 2007 as a salvage regimen for relapsed or refractory non-Hodgkin's lymphoma. To clarify the safety and efficacy of this regimen, w
Autor:
Sho Shibata, Yoko Takiuchi, Naoto Kawasaki, Yoshio Okamoto, Shojiro Inano, Akiko Fukunaga, Sumie Tabata, Ayako Arai, Ken-Ichi Imadome, Toshiyuki Kitano
Publikováno v:
International journal of hematology. 115(4)
Chronic active Epstein-Barr virus infection (CAEBV) is a systemic T- or NK-lymphoproliferative disorder (LPD) caused by EBV. Allogenic hematopoietic stem cell transplantation (HSCT) is the only curative therapy for CAEBV, but relapse sometimes occurs
Autor:
Yusuke Matsui, Kotaro Shirakawa, Keisuke Shindo, Noriyoshi Yoshinaga, Kayoko Nagata, Hirofumi Fukuda, Yoko Takiuchi, Akifumi Takaori-Kondo, Masayuki Kobayashi, Shunichi Takeda
Publikováno v:
Biochemical and Biophysical Research Communications. 513(1):93-98
Host DNA damage response molecules affect retroviral infection, as DNA intermediates of the viruses play essential roles in the viral life cycles. Although several such molecules have been reported, interactions between HIV-1 and host DNA damage resp
Autor:
Toshiyuki Kitano, Sumie Tabata, Naoto Kawasaki, Yoko Takiuchi, Yoshio Okamoto, Akiko Aiba, Yuki Oku, Naoki Yuhi, Sho Shibata, Shojiro Inano
Publikováno v:
International journal of hematology. 114(3)
We report a case of acquired hypofibrinogenemia with multiple myeloma presenting λ-type IgG monoclonal protein. The patient had anemia and renal deficiency, and also developed bleeding tendency due to severe coagulopathy. Her fibrinogen level was un
Autor:
Sho, Shibata, Toshiyuki, Kitano, Yoshio, Okamoto, Yoko, Takiuchi, Kazuyo, Yamamoto, Sumie, Tabata, Akiko, Aiba, Yuji, Yoshida, Yasuhito, Nannya, Seishi, Ogawa, Nobuyoshi, Arima
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 60(12)
In 2003, a 60-year-old man presenting with thrombocytosis was referred to our hospital. Laboratory tests revealed normal white blood cell count and hemoglobin level. Bone marrow examination showed an increased number of megakaryocytes with dysplasia.