Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yoko Sufu"'
Autor:
Yoriomi Hamada, Takeshi Yamamoto, Yoshihide Nakamura, Yoko Sufu-Shimizu, Takuma Nanno, Masakazu Fukuda, Makoto Ono, Tesuro Oda, Shinichi Okuda, Takeshi Ueyama, Shigeki Kobayashi, Masafumi Yano
Publikováno v:
Biochemistry and Biophysics Reports, Vol 21, Iss , Pp - (2020)
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart disease that causes heart failure and/or sudden cardiac death. Several desmosomal genes (DSC2, PKG, PKP2, DSP, and RyR2) are thought to be the causative gene inv
Externí odkaz:
https://doaj.org/article/ae65b70166a1457e884fd63ac98543fb
Autor:
Tetsuro Oda, Shinichi Okuda, Masafumi Yano, Takayoshi Kato, Yoko Sufu-Shimizu, Takeshi Yamamoto, Hitoshi Uchinoumi, Shigehiko Nishimura, Shigeki Kobayashi
Publikováno v:
Biochemical and Biophysical Research Communications. 524:431-438
Aims Ca2+/calmodulin-dependent protein kinase II (CaMKII) has been shown to induce aberrant Ca2+ release from the cardiac ryanodine receptor (RyR2) in various diseased hearts. However, the precise pathogenic mechanism remains to be elucidated. Here,
Autor:
Takuma Nanno, Shigeki Kobayashi, Masafumi Yano, Takeshi Ueyama, Yoko Sufu-Shimizu, Yoshihide Nakamura, Takeshi Yamamoto, Shinichi Okuda, Yoriomi Hamada, Tesuro Oda, Masakazu Fukuda, Makoto Ono
Publikováno v:
Biochemistry and Biophysics Reports, Vol 21, Iss, Pp-(2020)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart disease that causes heart failure and/or sudden cardiac death. Several desmosomal genes (DSC2, PKG, PKP2, DSP, and RyR2) are thought to be the causative gene invo
Autor:
Yoko, Sufu-Shimizu, Shinichi, Okuda, Takayoshi, Kato, Shigehiko, Nishimura, Hitoshi, Uchinoumi, Tetsuro, Oda, Shigeki, Kobayashi, Takeshi, Yamamoto, Masafumi, Yano
Publikováno v:
Biochemical and biophysical research communications. 524(2)
CaThe TG mice showed an increase in left ventricular end-diastolic diameter (LVEDD) and left ventricular end-systolic diameter (LVESD) with a reduction in LV fractional shortening (LVFS). The phosphorylation levels of Ser2814 in RyR2 and Thr287 in Ca
Autor:
Yoko Sufu, Takuma Nanno, Xiaojuan Xu, Go Fukui, Hironori Ishiguchi, Masafumi Yano, Shigehiko Nishimura, Shinichi Okuda, Shigeki Kobayashi, Takeshi Yamamoto, Makoto Ono, Yoriomi Hamada, Yoshihide Nakamura, Tetsuro Oda, Michiaki Kohno, Takayoshi Kato
Publikováno v:
Heart Rhythm. 15:905-914
Background Ryanodine receptor (RyR2) is known to be a causal gene of catecholaminergic polymorphic ventricular tachycardia (CPVT), an important inherited disease. Some of the human CPVT-associated mutations have been found in a domain (4026-4172) tha
Autor:
Shigehiko Nishimura, Yoko Sufu-Shimizu, Masakazu Fukuda, Masafumi Yano, Sachio Morimoto, Tetsuro Oda, Takeshi Yamamoto, Shigeki Kobayashi, Shinichi Okuda, Takayoshi Kato
Publikováno v:
Biochemical and Biophysical Research Communications. 496:1250-1256
Aims Cardiac Troponin T (TnT) mutation-linked familial hypertrophic cardiomyopathy (FHC) is known to cause sudden cardiac death at a young age. Here, we investigated the role of the Ca2+ release channel of the cardiac sarcoplasmic reticulum (SR), rya
Autor:
Shinichi, Okuda, Yoko, Sufu-Shimizu, Takayoshi, Kato, Masakazu, Fukuda, Shigehiko, Nishimura, Tetsuro, Oda, Shigeki, Kobayashi, Takeshi, Yamamoto, Sachio, Morimoto, Masafumi, Yano
Publikováno v:
Biochemical and biophysical research communications. 496(4)
Cardiac Troponin T (TnT) mutation-linked familial hypertrophic cardiomyopathy (FHC) is known to cause sudden cardiac death at a young age. Here, we investigated the role of the CaIn TG cardiomyocytes, the CaIn FHC-linked TnT-mutated hearts, RyR2 is s
Autor:
Shinichi Okuda, Yoko Sufu, Munemasa Okada, Masafumi Yano, Kosuke Uchida, Masatoshi Kato, Naofumi Matsunaga
Publikováno v:
Journal of Cardiology Cases. 12(5):162-165
We present the case of a 63-year-old woman presenting with a huge pelvic and retroperitoneal high flow arteriovenous malformation (AVM) causing high-output heart failure, who was treated with combined therapies, including transarterial embolization w
Autor:
Xiaojuan Xu, Shinichi Okuda, Masakazu Fukuda, Yoshihide Nakamura, Hiroyuki Kyushiki, Hironori Ishiguchi, Akihiro Hino, Wakako Murakami, Takako Maeda, Makoto Ono, Tetsuro Oda, Takeshi Yamamoto, Yoriomi Hamada, Noritaka Koseki, Shigeki Kobayashi, Masafumi Yano, Takuma Nanno, Takayoshi Kato, Go Fukui, Shigehiko Nishimura, Yoko Sufu
Publikováno v:
Heart rhythm. 14(1)
Background Calmodulin (CaM) is a key modulator of the channel gating function of the ryanodine receptor (RyR). Objective The purpose of this study was to investigate the pathogenic role of RyR-bound CaM in diastolic Ca 2+ leakage from the sarcoplasmi
Autor:
Shinichi Okuda, Shigeki Kobayashi, Takayoshi Kato, Masafumi Yano, Shigehiko Nishimura, Takeshi Yamamoto, Yoko Sufu, Tetsuro Oda, Masakazu Fukuda
Publikováno v:
Journal of Cardiac Failure. 21:S188