Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yoko Mizuno-Horikawa"'
Autor:
Yoko Mizuno-Horikawa, Shinya Mizuno
Publikováno v:
Pharmacology & Pharmacy. :481-492
Hyperkalemia is one of the most important risk factors in patients suffering from crush syndrome with rhabdomyolysis. Glycerol-injected animals have been used as an experimental model of rhabdomyolysis-induced acute kidney injury (AKI), but little in
Publikováno v:
The Journal of Veterinary Medical Science
Ischemic acute kidney injury (AKI) is the most key pathological event for accelerating progression to chronic kidney disease through vascular endothelial injury or dysfunction. Thus, it is critical to elucidate the molecular mechanism of endothelial
Autor:
Shinya Mizuno, Yoko Mizuno-Horikawa
Publikováno v:
Coronary Graft Failure ISBN: 9783319265131
Restenosis often occurs after placement of bare metal stents in arteries, and is histologically characterized by neointimal formation. In this process, endothelial cells (ECs) are injured and replaced with migrated vascular smooth muscle cells (VSMCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91477e93d57201212289bb504c30a2b5
https://doi.org/10.1007/978-3-319-26515-5_64
https://doi.org/10.1007/978-3-319-26515-5_64
Publikováno v:
Journal of Veterinary Medical Science. 73:1579-1584
Podocytes have a peculiar structure constituting slit diaphragm (SD) and foot process (FP), and play essential roles in the glomerular filtration barrier. There is now ample evidence that SD- and FP-associated molecules, such as podocin and CD2-assoc
Publikováno v:
Biomedical Research. 30:251-258
Acute renal failure (ARF) occurs in septic patients and is histologically characterized by tubular apical damages, including brush border breakdown. Nevertheless, little information is available to identify the apical injury at a molecular level. Typ
Autor:
Xiangchun Wang, Masaki Shigeta, Kengo Matsumura, Yoko Mizuno-Horikawa, Yoji Hata, Katsuya Higashida, Hiroki Ishida, Jianguo Gu, Kenji Yamamoto, Eiji Miyoshi, Naoyuki Taniguchi
Publikováno v:
Journal of Biological Chemistry. 282:15700-15708
The alpha1,6-fucosyl residue (core fucose) of glycoproteins is widely distributed in mammalian tissues and is altered under pathological conditions. A probe that specifically detects core fucose is important for understanding the role of this oligosa
Autor:
Yoko Mizuno-Horikawa, Akihiro Kondo, Naoyuki Taniguchi, Tomohiko Taguchi, Naofumi Uozumi, Jianguo Gu, Eiji Miyoshi, Tsutomu Nakagawa, Noriko Okuyama, Miyako Nakano
Publikováno v:
Journal of Biological Chemistry. 281:29797-29806
Fucosylated alpha-fetoprotein (AFP) is a highly specific tumor marker for hepatocellular carcinoma (HCC). However, the molecular mechanism by which serum level of fucosylated AFP increases in patients with HCC remains largely unknown. Here, we report
Autor:
Akihiro Kondo, Xiangchun Wang, Ikunoshin Kato, Yoko Mizuno-Horikawa, Nobuto Koyama, Wenzhe Li, Takatoshi Nakagawa, Naoyuki Taniguchi, Koichi Honke, Eiji Miyoshi, Jianguo Gu, Jinhua Jin
Publikováno v:
Glycobiology. 16:1007-1019
Alpha1,6-fucosyltransferase (Fut8) plays important roles in physiological and pathological conditions. Fut8-deficient (Fut8-/-) mice exhibit growth retardation, earlier postnatal death, and emphysema-like phenotype. To investigate the underlying mole
Autor:
Masaru Okabe, Carlos López-Otín, Naofumi Uozumi, Yoshiaki Tomiyama, Steven D. Shapiro, Katsuhisa Noda, Shinji Ihara, Jianguo Gu, Xiangchun Wang, Motoko Takahashi, Akihiro Kondo, Tomoyuki Kuwaki, Eiji Miyoshi, Yukihiro Yamaguchi, Junichi Fujii, Yoshiya Aze, Miyako Nakano, Seung Ho Lee, Koichi Honke, Keiichiro Suzuki, Shinya Inoue, Yoshitaka Ikeda, Yoko Mizuno-Horikawa, Wenzhe Li, Naoyuki Taniguchi, Michio Asahi
Publikováno v:
Proceedings of the National Academy of Sciences. 102:15791-15796
The core fucosylation (α1,6-fucosylation) of glycoproteins is widely distributed in mammalian tissues, and is altered under pathological conditions. To investigate physiological functions of the core fucose, we generated α1,6-fucosyltransferase ( F
Publikováno v:
Experimental Animals. 53:175-180
Diabetic nephropathy (DN), a major cause of end-stage chronic renal failure, is histologically characterized by glomerulosclerosis. To investigate the molecular mechanisms of DN, it is important to establish a stable model of glomerulosclerosis in mi