Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Yoko M. Ambrosini"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Salmonella enterica serovar Dublin (S. Dublin) is an important enteric pathogen affecting cattle and poses increasing public health risks. Understanding the pathophysiology and host–pathogen interactions of S. Dublin infection are critical
Externí odkaz:
https://doaj.org/article/fd6d2aa597254634ad29e2efbe94e414
Autor:
Itsuma Nagao, Minae Kawasaki, Takashi Goyama, Hyun Jung Kim, Douglas R. Call, Yoko M. Ambrosini
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT This study addresses the gap in translatable in vitro models for investigating Enterohemorrhagic E. coli (EHEC) infections, particularly relevant to both canine and human health. EHEC is known to induce acute colitis in dogs, leading to symp
Externí odkaz:
https://doaj.org/article/1690a78d71f949bdb0a017f0e7675cbc
Autor:
Itsuma Nagao, Yoko M. Ambrosini
Publikováno v:
BMC Molecular and Cell Biology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Emerging evidence underscores the responsiveness of the mammalian intestine to dietary cues, notably through the involvement of LGR5 + intestinal stem cells in orchestrating responses to diet-driven signals. However, the effects o
Externí odkaz:
https://doaj.org/article/bbe4a50c409241a3ba9695114693cd6a
Autor:
Minae Kawasaki, Yoko M. Ambrosini
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4914 (2024)
Enterohemorrhagic Escherichia coli (EHEC) is a critical public health concern due to its role in severe gastrointestinal illnesses in humans, including hemorrhagic colitis and the life-threatening hemolytic uremic syndrome. While highly pathogenic to
Externí odkaz:
https://doaj.org/article/3e55aec7dd8c4462b2381189d7207101
Autor:
Soyoun Min, Nam Than, Yong Cheol Shin, Grace Hu, Woojung Shin, Yoko M. Ambrosini, Hyun Jung Kim
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Here, we report a pathomimetic Leaky Gut Chip that recapitulates increased epithelial permeability and intestinal inflammation to assess probiotic intervention as live biotherapeutics. We leveraged a mechanodynamic human gut-on-a-chip (Gut C
Externí odkaz:
https://doaj.org/article/dbf8e70eea404d169e65e2c62ed6487d
Autor:
Peter J. Welsh, Kaylyn McDaniel, Elizabeth W. Goldsmith, Joshua D. Ramsay, Alan Conley, Tina Jo Owen, Yoko M. Ambrosini, Michela Ciccarelli
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
A 1-year-old male intact Miniature Schnauzer mix was presented for chronic intermittent hematuria. Abdominal ultrasonography revealed a large, fluid-filled cystic structure extending cranially and dorsally to the prostate. Computed tomography scan im
Externí odkaz:
https://doaj.org/article/ed85c50d9606425d853cd3c1f15a77e7
Autor:
Itsuma Nagao, Yoko M. Ambrosini
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
The study of biliary physiology and pathophysiology has long been hindered by the lack of in vitro models that accurately reflect the complex functions of the biliary system. Recent advancements in 3D organoid technology may offer a promising solutio
Externí odkaz:
https://doaj.org/article/1e63b25cfef041228427fdcc84a4d566
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 3, Pp 966-975 (2022)
Abstract Background Serum concentrations of 25‐hydroxyvitamin D (25(OH)VD) and C‐reactive protein (CRP) and von Willebrand's factor (vWF) concentration correlate with histopathologic disease grade and stage in chronic inflammatory and fibrotic he
Externí odkaz:
https://doaj.org/article/857977c9dfed4a12834d74579ef5943c
Publikováno v:
Frontiers in Medical Technology, Vol 4 (2022)
Animal organoid models derived from farm and companion animals have great potential to contribute to human health as a One Health initiative, which recognize a close inter-relationship among humans, animals and their shared environment and adopt mult
Externí odkaz:
https://doaj.org/article/833e4af860004afba6f8b745f97184fd
Autor:
Lawrance Chandra, Dana C. Borcherding, Dawn Kingsbury, Todd Atherly, Yoko M. Ambrosini, Agnes Bourgois-Mochel, Wang Yuan, Michael Kimber, Yijun Qi, Qun Wang, Michael Wannemuehler, N. Matthew Ellinwood, Elizabeth Snella, Martin Martin, Melissa Skala, David Meyerholz, Mary Estes, Martin E. Fernandez-Zapico, Albert E. Jergens, Jonathan P. Mochel, Karin Allenspach
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-21 (2019)
Abstract Background Large animal models, such as the dog, are increasingly being used for studying diseases including gastrointestinal (GI) disorders. Dogs share similar environmental, genomic, anatomical, and intestinal physiologic features with hum
Externí odkaz:
https://doaj.org/article/f1fd34c1386747e0ad2d608f68d2611e