Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yoko Kudo-Sakamoto"'
Autor:
Kei Nakamoto, Yoko Kudo-Sakamoto, Shungo Hikoso, Tomohito Ohtani, Yasushi Sakata, Fusako Sera
Publikováno v:
Circulation. 142
Introduction: Cachexia is a critical issue in patients with refractory heart failure (HF). Although the elevation of resting energy expenditure (REE) can progress cachexia through relatively insufficient calorie intake, the detail of REE in HF patien
Autor:
Issei Komuro, Hiroshi Akazawa, Ikuko Nakanomyo, Shigeomi Shimizu, Yoko Kudo-Sakamoto, Satoko Arakawa
Publikováno v:
Biochemical and Biophysical Research Communications. 467:1006-1011
In various pathological events, particularly in oxygen radical-mediated cell injury, both apoptosis and necrosis play essential roles. Apoptosis and some types of necrosis are induced via increases in mitochondrial membrane permeability, called mitoc
Autor:
Yingjie Qin, Kaoru Tateno, Jong-Kook Lee, Chizuru Yabumoto, Toshio Nagai, Yoshio Kobayashi, Yukako Ozasa, Hiroshi Akazawa, Issei Komuro, Toru Oka, Yoko Kudo-Sakamoto, Kaoru Ito, Masamichi Yano, Atsuhiko T. Naito, Tohru Minamino
Publikováno v:
Hypertension Research. 36:859-865
Notch signaling is involved in an intercellular communication mechanism that is essential for coordinated cell fate determination and tissue morphogenesis. The biological effects of Notch signaling are context-dependent. We investigated the functiona
Publikováno v:
Cardiovascular Drugs and Therapy. 27:155-160
A growing body of evidence has suggested that the use of angiotensin II (Ang II) type 1 (AT1) receptor blockers (ARBs) leads to a significant decrease in mortality and morbidity in patients with congestive heart failure. The AT1 receptor is a seven-t
Autor:
Masamichi Yano, Chizuru Yabumoto, Toru Oka, Yoko Kudo-Sakamoto, Hiroshi Akazawa, Yasushi Sakata, Jun-ichi Suzuki, Hiroki Yagi, Jong-Kook Lee, Yu Shimizu, Issei Komuro, Takehiro Kamo, Atsuhiko T. Naito
Publikováno v:
Scientific Reports
Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the rate-limiting step in the salvage pathway for nicotinamide adenine dinucleotide (NAD+) biosynthesis and thereby regulates the deacetylase activity of sirtuins. Here we show accommodative re
Autor:
Jong-Kook Lee, Etsuko Uejima, Masamichi Yano, Yu Shimizu, Chizuru Yabumoto, Rie Yamamoto, Atsuhiko T. Naito, Issei Komuro, Takehiro Kamo, Toru Oka, Akiko Saga-Kamo, Tomokazu Sumida, Hiroshi Akazawa, Yasushi Sakata, Hiroki Yagi, Jun-ichi Suzuki, Yoko Kudo-Sakamoto
Publikováno v:
Scientific Reports
Disruption of angiotensin II type 1 (AT1) receptor prolonged life span in mice. Since aging-related decline in skeletal muscle function was retarded in Atgr1a−/− mice, we examined the role of AT1 receptor in muscle regeneration after injury. Admi
Autor:
Hiroshi Akazawa, Masamichi Yano, Jong-Kook Lee, Takaomi C. Saido, Chizuru Yabumoto, Kaoru Ito, Toru Oka, Jun-ichi Suzuki, Yasushi Sakata, Issei Komuro, Atsuhiko T. Naito, Yoko Kudo-Sakamoto, Jiro Takano
Publikováno v:
The Journal of biological chemistry. 289(28)
Enzymatic proteolysis by calpains, Ca(2+)-dependent intracellular cysteine proteases, has been implicated in pathological processes such as cellular degeneration or death. Here, we investigated the role of calpain activation in the hearts subjected t
Publikováno v:
Current pharmaceutical design. 19(17)
The octapeptide angiotensin II (Ang II) plays a homeostatic role in the regulation of blood pressure and water and electrolyte balance, and also contributes to the progression of cardiovascular remodeling. Ang II activates Ang II type 1 (AT1) recepto
Autor:
Chizuru Yabumoto, Yoko Kudo-Sakamoto, Pierre Paradis, Kaoru Ito, Hiroshi Akazawa, Yukako Ozasa, Rie Yamamoto, Masamichi Yano, Noritaka Yasuda, Toru Oka, Atsuhiko T. Naito, Ichiro Shiojima, Tohru Minamino, Kouichi Tamura, Satoshi Umemura, Mona Nemer, Issei Komuro, Ippei Shimizu
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 59(3)
The angiotensin II (Ang II) type 1 (AT 1 ) receptor mainly mediates the physiological and pathological actions of Ang II, but recent studies have suggested that AT 1 receptor inherently shows spontaneous constitutive activity even in the absence of A
Autor:
Yoko Kudo-Sakamoto1, Hiroshi Akazawa2,3 akazawah-tky@umin.ac.jp, Kaoru Ito4, Jiro Takano5, Masamichi Yano1, Chizuru Yabumoto1, Atsuhiko T. Naito3,6, Toru Oka1,3, Jong-Kook Lee7, Yasushi Sakata1,2, Jun-ichi Suzuki, Takaomi C. Saido5, Issei Komuro3,6 komuro-tky@umin.ac.jp
Publikováno v:
Journal of Biological Chemistry. 7/11/2014, Vol. 289 Issue 28, p19408-19419. 12p.