Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Yoko Kosaka"'
Autor:
Patrick A. Flynn, Mark D. Long, Yoko Kosaka, Nicola Long, Jessica S. Mulkey, Jesse L. Coy, Anupriya Agarwal, Evan F. Lind
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Dendritic cells (DC) are mediators between innate and adaptive immune responses to pathogens and tumors. DC development is determined by signaling through the receptor tyrosine kinase Fms-like tyrosine kinase 3 (FLT3) in bone marrow myeloid progenito
Externí odkaz:
https://doaj.org/article/3e30080c310749e18369d64f85070101
Autor:
Hiromichi Yamane, Nobuaki Ochi, Ayaka Mimura, Yoko Kosaka, Naruhiko Ichiyama, Tatsuyuki Kawahara, Yasunari Nagasaki, Hidekazu Nakanishi, Nagio Takigawa
Publikováno v:
Palliative Medicine Reports, Vol 4, Iss 1, Pp 278-287 (2023)
Background: In Japan, the number of patients with aggressive hematological malignancies (PHMs) admitted at the palliative care unit (PCU) in their end-of-life (EOL) stage was fewer than that of patients with solid tumors due to several reasons. The a
Externí odkaz:
https://doaj.org/article/bd058afdb6394ef2913727a56a17652c
Autor:
Hiromichi Yamane, Yasunari Nagasaki, Tatsuyuki Kawahara, Naruhiko Ichiyama, Yoko Kosaka, Nobuaki Ochi, Hidekazu Nakanishi, Nagio Takigawa
Publikováno v:
Thoracic Cancer, Vol 14, Iss 16, Pp 1538-1539 (2023)
Externí odkaz:
https://doaj.org/article/fa2bee93263441289abe0e5adc6e4652
Autor:
Patrick Flynn, Yoko Kosaka, Matthew Newman, Kyle Romine, Hyun-Jun Cho, Kaelan Byrd, Jesse Coy, Christopher Loo, Evan Lind
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/59f3b261c10142a1a090779f8425025e
Autor:
Flynn, Patrick A., Long, Mark D., Yoko Kosaka, Long, Nicola, Mulkey, Jessica S., Coy, Jesse L., Agarwal, Anupriya, Lind, Evan F.
Publikováno v:
Frontiers in Immunology; 2024, p1-15, 15p
Autor:
Kaycee B. Moshofsky, Hyun J. Cho, Guanming Wu, Kyle A. Romine, Matthew T. Newman, Yoko Kosaka, Shannon K. McWeeney, Evan F. Lind
Publikováno v:
Blood Advances, Vol 3, Iss 20, Pp 3038-3051 (2019)
Abstract: Acute myeloid leukemia (AML) remains difficult to treat due to mutational heterogeneity and the development of resistance to therapy. Targeted agents, such as MEK inhibitors, may be incorporated into treatment; however, the impact of MEK in
Externí odkaz:
https://doaj.org/article/d33dcf95792246069121c242dfdc873d
Autor:
Kyle A. Romine, Kevin MacPherson, Hyun-jun Cho, Yoko Kosaka, Patrick A. Flynn, Kaelan H. Byrd, Jesse L. Coy, Matthew T. Newman, Ravina Pandita, Christopher P. Loo, Jaime Scott, Andrew C. Adey, Evan F. Lind
Publikováno v:
Leukemia. 37:580-592
Many acute myeloid leukemia (AML) patients exhibit hallmarks of immune exhaustion, such as increased myeloid-derived suppressor cells, suppressive regulatory T cells and dysfunctional T cells. Similarly, we have identified the same immune-related fea
Autor:
Olivia M. Lucero, Ji-Ann Lee, Jenna Bowman, Kara Johnson, Gopal Sapparapu, John K. Thomas, Guang Fan, Bill H. Chang, Karina Thiel-Klare, Christopher A. Eide, Craig Okada, Mike Palazzolo, Evan Lind, Yoko Kosaka, Brian J. Druker, Nicholas Lydon, Peter M. Bowers
Publikováno v:
Clinical Cancer Research.
Purpose: Targeted therapeutics are a goal of medicine. Methods for targeting T-cell lymphoma lack specificity for the malignant cell, leading to elimination of healthy cells. The T-cell receptor (TCR) is designed for antigen recognition. T-cell malig
Autor:
Kyle Romine, Hyun-jun Cho, Yoko Kosaka, Patrick Flynn, Kaelan Byrd, Jesse Coy, Matthew Newman, Jamie Scott, Andrew Adey, Evan Lind
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Filemon S. Dela Cruz, Hiroyuki Yoda, Calvin J. Kuo, William C. Hahn, Kelly Kersten, Olivier Gevaert, Michitaka Nakano, Bruce K. Hua, Yohannes Tsehay, Han Liang, Yun Rose Li, Taofeek K. Owonikoko, Yunqi Yan, Katherine N. Liu, Stephen E. Kurtz, Andrew J. Ewald, Gordon B. Mills, Matthew Dunworth, Yuhao Wang, Eloise M. Grasset, Joseph Estabrook, Nicola Long, Vasanthi S. Viswanathan, Bridget Robinson, Shubhroz Gill, Matthew C. Perrone, Ken Chen, Suresh S. Ramalingam, Robert T. Manguso, Asmita Bhattacharya, Andrea Califano, Wei Zhou, Yuhong Du, Elodie Henriet, Jordana Brown, Francisca Vazquez, Michael T. McManus, Manisha Warrier, Gabriel Eades, Anuja Sathe, Yilong Zou, Yoko Kosaka, Matthew A. Reyna, Theodore P. Braun, Daniela S. Gerhard, Matthew F. Krummel, Allan Balmain, Tamilla Nechiporuk, Hanlee P. Ji, Quin Morrow, Emek Demir, Pablo Tamayo, Jessica Minnier, Michael C. Bassik, Kevin Watanabe-Smith, Xiulei Mo, Qi-Wen Fan, Nicole Nasholm, Sagar Lonial, Stuart L. Schreiber, Brent R. Stockwell, Nina K. Serwas, Sourav Bandyopadhyay, Brian J. Druker, Christina Curtis, Yuan-Hung Lo, Olga Nikolova, Qiankun Niu, Veena Padmanaban, Yuchen Ge, Cristina E. Tognon, Anupriya Agarwal, Christopher J. Kemp, Kremena Karagyozova, Haian Fu, Trevor Bivona, Dan Georgess, Nidhi Sahni, Stefan Oberlin, Issac S. Chan, Michael G. Lerner, Matt Hangauer, Jennifer Saultz, Wing Hing Wong, Ilya Shmulevich, Christin Schmidt, Yasir Suhail, Andy Kaempf, Alan Ashworth, Saumya R. Bollam, Tanaz Sharifnia, Jesse S. Boehm, Kasper Karlsson, Carlos S. Moreno, Neil Tay, Michael Grzadkowski, Kevin C. Brennan, Subhashini Jagu, Elizabeth M. Swisher, Ben Deneen, Jessica A. Talamas, Amber R. Smith, Joel S. Bader, Vlado Dančík, Andrew L. Kung, William A. Weiss, Hildur Knutsdottir, Tania Q. Vu, Lee Cooper, Kanako Yuki, Wei-Ching Chen, Bridget K. Wagner, Evan F. Lind, Josh Dempster, Marie Menard, Carla Grandori, Andrey A. Ivanov, William Kim, Jeffrey W. Tyner, Jonathan S. Weissman, Thomas Jacob, Paul A. Clemons, Jitong Cai, Kaitlyn Spees, Dan S. Kaufman
Publikováno v:
Cell, vol 184, iss 5
Cell
Cell
The characterization of cancer genomes has provided insight into somatically altered genes across tumors, transformed our understanding of cancer biology, and enabled tailoring of therapeutic strategies. However, the function of most cancer alleles r