Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yoko Kitawaki"'
Autor:
Hisaaki Taniguchi, Kiyotsugu Yoshikawa, Shun-ichiro Iemura, Katsuya Okawa, Shimpei Kawamoto, Il-mi Okazaki, Hitoshi Nagaoka, Maki Kobayashi, Reiko Shinkura, Tasuku Honjo, Tohru Natsume, Yoko Kitawaki
Publikováno v:
Proceedings of the National Academy of Sciences. 108:7920-7925
Activation-induced cytidine deaminase (AID) is shown to be essential and sufficient to induce two genetic alterations in the Ig loci: class switch recombination (CSR) and somatic hypermutation (SHM). However, it is still unknown how a single-molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d265feec72b5775d18c3bea11122ae
https://doi.org/10.1073/pnas.1104423108
https://doi.org/10.1073/pnas.1104423108
Autor:
Mikiyo Nakata, Kazuo Kinoshita, Hitoshi Nagaoka, Reiko Shinkura, Maki Kobayashi, Andre Stanlie, Yoko Kitawaki, Nasim A. Begum, Masamichi Muramatsu, Tomomitsu Doi, Tasuku Honjo, Lucia Kato, Il-mi Okazaki, Masatoshi Aida
Publikováno v:
Proceedings of the National Academy of Sciences. 106:22375-22380
To initiate class switch recombination (CSR) activation-induced cytidine deaminase (AID) induces staggered nick cleavage in the S region, which lies 5 to each Ig constant region gene and is rich in palindromic sequences. Topoisomerase 1 (Top1) contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5124e9b1961a3c9b28459b94377cc691
https://doi.org/10.1073/pnas.0911879106
https://doi.org/10.1073/pnas.0911879106
Autor:
Tasuku Honjo, Atsushi Takai, Tsutomu Chiba, Hiroshi Hiai, Kazuo Kinoshita, Munehiro Uemura, Il-mi Okazaki, Hiroyuki Marusawa, Yoko Kitawaki, Takae Toyoshima, S. Yamada
Publikováno v:
Oncogene. 28(4)
Activation-induced cytidine deaminase (AID), the only enzyme that is known to be able to induce mutations in the human genome, is required for somatic hypermutation and class-switch recombination in B lymphocytes. Recently, we showed that AID is impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752c98e4686eab1bbf80c69cccb2f07e
https://pubmed.ncbi.nlm.nih.gov/18997814
https://pubmed.ncbi.nlm.nih.gov/18997814