Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yoko Hosaka"'
Autor:
Hiroshi Kobayashi, Song Ho Chang, Daisuke Mori, Shozo Itoh, Makoto Hirata, Yoko Hosaka, Yuki Taniguchi, Keita Okada, Yoshifumi Mori, Fumiko Yano, Ung-il Chung, Haruhiko Akiyama, Hiroshi Kawaguchi, Sakae Tanaka, Taku Saito
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Rela is a transcription factor shown to have seemingly contradictory roles in anabolism and catabolism of cartilage. Here the authors find that Rela prevents chondrocyte apoptosis and that homozygous knockout causes accelerated osteoarthritis in adul
Externí odkaz:
https://doaj.org/article/6fd2362e5f6846e1b0eafd3f836e0325
Autor:
Yuma Makii, Meiko Asaka, Susumu Setogawa, Soichiro Fujiki, Yoko Hosaka, Fumiko Yano, Hiroyuki Oka, Sakae Tanaka, Naoshi Fukui, Dai Yanagihara, Taku Saito
Publikováno v:
Journal of Orthopaedic Surgery, Vol 26 (2018)
Purpose: Joint pain is the most common symptom of osteoarthritis (OA); however, its mechanism remains unclarified. The present study investigated hindlimb motion during locomotion on the treadmill using a three-dimensional (3D) motion analysis system
Externí odkaz:
https://doaj.org/article/309c8f5ff2ca419ca9329f9309e14d03
Autor:
Keita Okada, Atsushi Fukai, Daisuke Mori, Yoko Hosaka, Fumiko Yano, Ung-il Chung, Hiroshi Kawaguchi, Sakae Tanaka, Toshiyuki Ikeda, Taku Saito
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115169 (2014)
Transcription factors SOX9, SOX5 and SOX6 are indispensable for generation and differentiation of chondrocytes. However, molecular mechanisms to induce the SOX genes are poorly understood. To address this issue, we previously determined the human emb
Externí odkaz:
https://doaj.org/article/a86c49edcc46401eaaa958d4b0319ddb
Autor:
Koji Yamada, Shinichi Yamamoto, Yoji Mikami, Tomohiro Shinozaki, Yoko Hosaka, Takeshi Ando, Sakae Tanaka, Kosei Nagata, Saki Ogura, Yuki Ohnishi, Hiroyuki Kanai
Publikováno v:
Journal of Orthopaedic Science. 27:1056-1059
Background Necrotizing fasciitis (NF) is a life-threatening and acute progressive soft tissue infection and needs early surgical intervention, that is, debridement or amputation. Surgical strategy or prognosis is influenced by the speed of progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea87d20b339da42b51740cc7bc2b66b
https://doi.org/10.1016/j.jos.2021.06.007
https://doi.org/10.1016/j.jos.2021.06.007
Publikováno v:
JBJS Case Connector. 11
Case We report a case of irreducible chronic volar dislocation of the distal radioulnar joint (DRUJ) after surgery for distal radius fracture. The patient underwent volar locking plate fixation for distal radius fracture. Despite the satisfactory ali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be874555139951a3d6c62a272cc6694
https://doi.org/10.2106/jbjs.cc.20.00838
https://doi.org/10.2106/jbjs.cc.20.00838
Autor:
Alea A. Mills, Hiroshi Inui, Haruhiko Akiyama, Yoko Hosaka, Shuji Taketomi, Hiroshi Kawaguchi, Song Ho Chang, Shurei Sugita, Ung-il Chung, Fumiko Yano, Toshiyuki Ikeda, Hiroshi Kobayashi, Taku Saito, Sakae Tanaka, Manabu Kawata, Daisuke Mori, Keita Okada, Yuki Taniguchi
Publikováno v:
Arthritis & Rheumatology. 69:598-609
Objective: Transcription factor p63, of the p53 family, regulates cell proliferation, survival, and apoptosis in various cells and tissues. This study was undertaken to examine the expression and roles of p63 transcript variants in the mouse growth p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bd9750494dad31fc27980e76707666a
https://doi.org/10.1002/art.39976
https://doi.org/10.1002/art.39976
Autor:
Yasunori Omata, Yoko Hosaka, Ryota Yamagami, Joo-ri Kim-Kaneyama, Takumi Matsumoto, Toshinobu Omiya, Tetsuro Yasui, Shuji Taketomi, Sakae Tanaka, Ung-il Chung, Hiroshi Inui, Fumiko Yano, Taku Saito, Daisuke Mori, Song Ho Chang
Publikováno v:
Osteoarthritis and Cartilage. 24(4):688-697
Summary Objective Prevalence of ankle osteoarthritis (OA) is lower than that of knee OA, however, the molecular mechanisms underlying the difference remain unrevealed. In the present study, we developed mouse ankle OA models for use as tools to inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdac1e57d19ad7c04ae65a2b4ab0da23
Autor:
Sakae Tanaka, Meiko Asaka, Hiroyuki Oka, Yuma Makii, Susumu Setogawa, Soichiro Fujiki, Taku Saito, Fumiko Yano, Yoko Hosaka, Naoshi Fukui, Dai Yanagihara
Publikováno v:
Journal of Orthopaedic Surgery, Vol 26 (2018)
Purpose: Joint pain is the most common symptom of osteoarthritis (OA); however, its mechanism remains unclarified. The present study investigated hindlimb motion during locomotion on the treadmill using a three-dimensional (3D) motion analysis system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328afc7b0600c7da4d5cf66650a460bc
https://pubmed.ncbi.nlm.nih.gov/29661110
https://pubmed.ncbi.nlm.nih.gov/29661110
Publikováno v:
JBJS Case Connector; Apr-Jun2021, Vol. 11 Issue 2, p1-6, 6p
Autor:
Shurei Sugita, Ung-il Chung, Haruhiko Akiyama, Yuki Taniguchi, Yoko Hosaka, Makoto Hirata, Hiroshi Kawaguchi, Hiroshi Kobayashi, Atsushi Fukai, Tomohiro Hikata, Taku Saito
Publikováno v:
Proceedings of the National Academy of Sciences. 110:1875-1880
Here we examined the involvement of Notch signaling in the endochondral ossification process, which is crucial for osteoarthritis (OA) development. Intracellular domains of Notch1 and -2 were translocated into the nucleus of chondrocytes with their d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba97952c0df90cdcabad18b5a60b870
https://doi.org/10.1073/pnas.1207458110
https://doi.org/10.1073/pnas.1207458110