Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yoko Fukuda-Yuzawa"'
Autor:
Sudha Sunil Rajderkar, Kitt Paraiso, Maria Luisa Amaral, Michael Kosicki, Laura E. Cook, Fabrice Darbellay, Cailyn H. Spurrell, Marco Osterwalder, Yiwen Zhu, Han Wu, Sarah Yasmeen Afzal, Matthew J. Blow, Guy Kelman, Iros Barozzi, Yoko Fukuda-Yuzawa, Jennifer A. Akiyama, Veena Afzal, Stella Tran, Ingrid Plajzer-Frick, Catherine S. Novak, Momoe Kato, Riana D. Hunter, Kianna von Maydell, Allen Wang, Lin Lin, Sebastian Preissl, Steven Lisgo, Bing Ren, Diane E. Dickel, Len A. Pennacchio, Axel Visel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The genetic basis of human facial variation and craniofacial birth defects remains poorly understood. Distant-acting transcriptional enhancers control the fine-tuned spatiotemporal expression of genes during critical stages of craniofacial d
Externí odkaz:
https://doaj.org/article/ad066eccb027472d812a541544ff79a2
Autor:
Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li, Ana Alcaina Caro, Yoko Fukuda-Yuzawa, Guy Kelman, Adyam Akeza, Matthew J. Blow, Quan Pham, Anne N. Harrington, Janeth Godoy, Eman M. Meky, Kianna von Maydell, Riana D. Hunter, Jennifer A. Akiyama, Catherine S. Novak, Ingrid Plajzer-Frick, Veena Afzal, Stella Tran, Javier Lopez-Rios, Michael E. Talkowski, K. C. Kent Lloyd, Bing Ren, Diane E. Dickel, Axel Visel, Len A. Pennacchio
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Topologically associating domain (TAD) boundaries partition the genome into distinct regulatory territories. Anecdotal evidence suggests that their disruption may interfere with normal gene expression and cause disease phenotypes1–3, but t
Externí odkaz:
https://doaj.org/article/e14ddea1acbd44d0886ef92596b4bbe5
Autor:
Diane E. Dickel, Iros Barozzi, Yiwen Zhu, Yoko Fukuda-Yuzawa, Marco Osterwalder, Brandon J. Mannion, Dalit May, Cailyn H. Spurrell, Ingrid Plajzer-Frick, Catherine S. Pickle, Elizabeth Lee, Tyler H. Garvin, Momoe Kato, Jennifer A. Akiyama, Veena Afzal, Ah Young Lee, David U. Gorkin, Bing Ren, Edward M. Rubin, Axel Visel, Len A. Pennacchio
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Identification of non-coding variants has outstripped our ability to annotate and interpret them. Dickel et al. present a compendium of over 80,000 putative human heart enhancers and demonstrate that two conserved enhancers are required for proper ca
Externí odkaz:
https://doaj.org/article/b001d43a207246388e738ba39f9b2876
Autor:
Cailyn H. Spurrell, Iros Barozzi, Michael Kosicki, Brandon J. Mannion, Matthew J. Blow, Yoko Fukuda-Yuzawa, Neil Slaven, Sarah Y. Afzal, Jennifer A. Akiyama, Veena Afzal, Stella Tran, Ingrid Plajzer-Frick, Catherine S. Novak, Momoe Kato, Elizabeth A. Lee, Tyler H. Garvin, Quan T. Pham, Anne N. Kronshage, Steven Lisgo, James Bristow, Thomas P. Cappola, Michael P. Morley, Kenneth B. Margulies, Len A. Pennacchio, Diane E. Dickel, Axel Visel
Publikováno v:
Cell reports, vol 40, iss 12
Heart disease is associated with re-expression of key transcription factors normally active only during prenatal development of the heart. However, the impact of this reactivation on the regulatory landscape in heart disease is unclear. Here, we use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e08487b6c3944840b9b551f82b259d
https://escholarship.org/uc/item/2zk8j1fx
https://escholarship.org/uc/item/2zk8j1fx
Autor:
Michael E. Talkowski, Sudha Rajderkar, Catherine S. Novak, Yanxiao Zhang, Kianna von Maydell, Quan Pham, Ingrid Plajzer-Frick, Stella Tran, Anne N. Harrington, Axel Visel, Eman Meky, Diane E. Dickel, Bing Ren, Rong Hu, Adyam Akeza, Janeth Godoy, Matthew J. Blow, Len A. Pennacchio, Yoko Fukuda-Yuzawa, Guy Kelman, Veena Afzal, Kevin C K Lloyd, Yiwen Zhu, Iros Barozzi, Bin Li
Author(s): Rajderkar, Sudha; Barozzi, Iros; Zhu, Yiwen; Hu, Rong; Zhang, Yanxiao; Li, Bin; Fukuda-Yuzawa, Yoko; Kelman, Guy; Akeza, Adyam; Blow, Matthew; Pham, Quan; Harrington, Anne; Godoy, Janeth; Meky, Eman; von Maydell, Kianna; Novak, Catherine;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc95d9845da576526911b623218e333
https://doi.org/10.1101/2021.05.06.443037
https://doi.org/10.1101/2021.05.06.443037
Autor:
Anne N. Harrington, Emrah Gumusgoz, Kevin Y. Yip, Anurag Sethi, Axel Visel, Elizabeth Lee, Catherine S. Novak, Mengting Gu, Richard E. Sutton, Ingrid Plajzer-Frick, Iros Barozzi, Momoe Kato, Tyler H. Garvin, Len A. Pennacchio, Quan Pham, Koon-Kiu Yan, Brandon J. Mannion, Yoko Fukuda-Yuzawa, Landon L Chan, Veena Afzal, Diane E. Dickel, Mark Gerstein, Jennifer A. Akiyama, Chengfei Yan, Joel Rozowsky
Publikováno v:
Nature methods, vol 17, iss 8
Nature methods
Nature methods
Enhancers are important non-coding elements, but they have traditionally been hard to characterize experimentally. The development of massively parallel assays allows the characterization of large numbers of enhancers for the first time. Here, we dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53516be68668786171cea79b7f4b526f
https://escholarship.org/uc/item/9q55f3n7
https://escholarship.org/uc/item/9q55f3n7
Autor:
Axel Visel, Catherine S. Novak, Tyler H. Garvin, Hongbo Yang, Anne N. Harrington, Diane E. Dickel, Yin Shen, Kyle J. Gaulton, J. Michael Cherry, Bin Li, Quan T. Pham, Yunjiang Qiu, Mengchi Wang, Jean M. Davidson, Bo Ding, Elizabeth Lee, Ingrid Plajzer-Frick, Sora Chee, Sebastian Preissl, Jee Yun Han, Diane Trout, Henry Amrhein, Yupeng He, Jennifer A. Akiyama, Momoe Kato, Joseph R. Ecker, Veena Afzal, J. Seth Strattan, Yuan Zhao, Bo Zhang, Wei Wang, Len A. Pennacchio, David U. Gorkin, Brian A. Williams, Iros Barozzi, Ah Young Lee, Hui Huang, Yoko Fukuda-Yuzawa, Yanxiao Zhang, Brandon J. Mannion, Bing Ren, Andre Wildberg, Joshua Chiou
Publikováno v:
Nature, vol 583, iss 7818
Nature
Nature
The Encyclopedia of DNA Elements (ENCODE) project has established a genomic resource for mammalian development, profiling a diverse panel of mouse tissues at 8 developmental stages from 10.5 days after conception until birth, including transcriptomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f247784ec64efc5f84e457834a66464
https://escholarship.org/uc/item/5ch369qm
https://escholarship.org/uc/item/5ch369qm
Autor:
Elizabeth Lee, Momoe Kato, Quan Pham, Veena Afzal, James Bristow, Cailyn H. Spurrell, Iros Barozzi, Stella Tran, Matthew J. Blow, Steven Lisgo, Michael Morley, Kenneth B. Margulies, Diane E. Dickel, Axel Visel, Len A. Pennacchio, Catherine S. Novak, Tyler H. Garvin, Yoko Fukuda-Yuzawa, Thomas P. Cappola, Sarah Y. Afzal, Anne N. Harrington, Jennifer A. Akiyama, Ingrid Plajzer-Frick, Brandon J. Mannion
Author(s): Spurrell, Cailyn; Barozzi, Iros; Mannion, Brandon; Blow, Matthew; Fukuda-Yuzawa, Yoko; Afzal, Sarah; Akiyama, Jennifer; Afzal, Veena; Tran, Stella; Plajzer-Frick, Ingrid; Novak, Catherine; Kato, Momoe; Lee, Elizabeth; Garvin, Tyler; Pham,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1669c3f0dad17f9dc73f88a70617c3c3
https://escholarship.org/uc/item/1b18p0b8
https://escholarship.org/uc/item/1b18p0b8
Autor:
Catherine S. Novak, Quan T. Pham, Bo Ding, Diane Trout, Ingrid Plajzer-Frick, Yuan Zhao, J. Seth Strattan, Elizabeth Lee, Jee Yun Han, Bin Li, Jennifer A. Akiyama, Veena Afzal, Hongbo Yang, Ah Young Lee, Joseph R. Ecker, Sebastian Preissl, Kyle J. Gaulton, Anne N. Harrington, Momoe Kato, Andre Wildberg, Yupeng He, Diane E. Dickel, Tyler H. Garvin, Jean M. Davidson, Joshua Chiou, Bo Zhang, Len A. Pennacchio, Hui Huang, Yoko Fukuda-Yuzawa, Iros Barozzi, Brian A. Williams, Yanxiao Zhang, Yunjiang Qiu, Sora Chee, Axel Visel, Henry Amrhein, Bing Ren, J. Michael Cherry, Wei Wang, Mengchi Wang, David U. Gorkin, Yin Shen, Brandon J. Mannion
Publikováno v:
Nature
Nature, vol 589, iss 7842
Nature, vol 586, iss 7831
Nature, vol 589, iss 7842
Nature, vol 586, iss 7831
The Encyclopedia of DNA Elements (ENCODE) project has established a genomic resource for mammalian development, profiling a diverse panel of mouse tissues at 8 developmental stages from 10.5 days after conception until birth, including transcriptomes
Autor:
Marco Osterwalder, Catherine S. Pickle, Yiwen Zhu, Elizabeth Lee, David U. Gorkin, Ah Young Lee, Momoe Kato, Jennifer A. Akiyama, Ingrid Plajzer-Frick, Brandon J. Mannion, Axel Visel, Dalit May, Edward M. Rubin, Diane E. Dickel, Bing Ren, Cailyn H. Spurrell, Tyler H. Garvin, Iros Barozzi, Len A. Pennacchio, Yoko Fukuda-Yuzawa, Veena Afzal
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Dickel, DE; Barozzi, I; Zhu, Y; Fukuda-Yuzawa, Y; Osterwalder, M; Mannion, BJ; et al.(2016). Genome-wide compendium and functional assessment of in vivo heart enhancers. Nature Communications, 7. doi: 10.1038/ncomms12923. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/750894b2
Nature Communications
Nature communications, vol 7, iss 1
Dickel, DE; Barozzi, I; Zhu, Y; Fukuda-Yuzawa, Y; Osterwalder, M; Mannion, BJ; et al.(2016). Genome-wide compendium and functional assessment of in vivo heart enhancers. Nature Communications, 7. doi: 10.1038/ncomms12923. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/750894b2
Nature Communications
Nature communications, vol 7, iss 1
Whole-genome sequencing is identifying growing numbers of non-coding variants in human disease studies, but the lack of accurate functional annotations prevents their interpretation. We describe the genome-wide landscape of distant-acting enhancers a