Zobrazeno 1 - 10
of 880
pro vyhledávání: '"Yoko Takahashi"'
Autor:
Kazutaka Otsuji, Yoko Takahashi, Tomo Osako, Takayuki Kobayashi, Toshimi Takano, Sumito Saeki, Liying Yang, Satoko Baba, Kohei Kumegawa, Hiromu Suzuki, Tetsuo Noda, Kengo Takeuchi, Shinji Ohno, Takayuki Ueno, Reo Maruyama
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-15 (2024)
Abstract Metastasis is a complex process that remains poorly understood at the molecular levels. We profiled single-cell transcriptomic, genomic, and epigenomic changes associated with cancer cell progression, chemotherapy resistance, and metastasis
Externí odkaz:
https://doaj.org/article/179f0fdfd216418d9862aee1f1cbbaf0
Autor:
Ryo Takada, Miki Fujiwara, Masatoshi Maki, Naoyuki Nomura, Shintaro Kono, Akira Fujita, Hiroshi Masumoto, Yoko Takahashi, Yasuhisa Hasegawa, Koji Tamura
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Background Ipilimumab (Ipi) plus nivolumab (Nivo) is the recommended first-line treatment for renal cell carcinoma (RCC). This report describes a case where pancreatic metastases disappeared after only two courses of Ipi + Nivo therapy. The
Externí odkaz:
https://doaj.org/article/520b8f63e6f345f1bc3b0b880b5ef58a
Autor:
Austin T.K. Hoke, Yoko Takahashi, Michelle R. Padget, Javier Gomez, Moran Amit, Jared Burks, Diana Bell, Tongxin Xie, Patrick Soon-Shiong, James W. Hodge, Ehab Y. Hanna, Nyall R. London, Jr
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101943- (2024)
Purpose: Sinonasal undifferentiated carcinoma (SNUC) is a rare, aggressive malignancy of the sinonasal cavity with poor prognosis and limited treatment options. To investigate the potential for SNUC sensitivity to combinatory immunotherapy, we perfor
Externí odkaz:
https://doaj.org/article/21390839f1884ba499e36505b6266d78
Autor:
Yoko Takahashi, Ehab Y. Hanna
Publikováno v:
European Journal of Rhinology and Allergy, Vol 6, Iss 2, Pp 37-41 (2023)
Externí odkaz:
https://doaj.org/article/22ca81f0de694cc7a49ba9a818b25d2d
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Background While cancer is a risk factor for developing thromboembolism, so is the use of molecularly targeted therapies. This study aimed to determine whether thromboembolism incidence differed between vascular endothelial growth factor (VE
Externí odkaz:
https://doaj.org/article/19222366de48486e9e7f1d03dec4a732
Autor:
Kazunori Sato, Yuta Yamazaki, Yoshihiro Kameyama, Koji Watanabe, Eriko Kitahara, Koshiro Haruyama, Yoko Takahashi, Yuji Fujino, Tomofumi Yamaguchi, Tadamitsu Matsuda, Hitoshi Makabe, Reina Isayama, Yuhei Murakami, Mami Tani, Kaoru Honaga, Kozo Hatori, Yutaka Oji, Yuji Tomizawa, Taku Hatano, Nobutaka Hattori, Toshiyuki Fujiwara
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
ObjectivesTo investigate the construct validity of the Trunk Impairment Scale (TIS), which was developed to assess trunk impairment in patients with stroke, in patients with Parkinson’s disease (PD).DesignThis retrospective, cross-sectional study e
Externí odkaz:
https://doaj.org/article/6375496809e74e66b330b3c2c6a18691
Autor:
Sumito Saeki, Kohei Kumegawa, Yoko Takahashi, Liying Yang, Tomo Osako, Mahmut Yasen, Kazutaka Otsuji, Kenichi Miyata, Kaoru Yamakawa, Jun Suzuka, Yuri Sakimoto, Yukinori Ozaki, Toshimi Takano, Takeshi Sano, Tetsuo Noda, Shinji Ohno, Ryoji Yao, Takayuki Ueno, Reo Maruyama
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background The intratumor heterogeneity (ITH) of cancer cells plays an important role in breast cancer resistance and recurrence. To develop better therapeutic strategies, it is necessary to understand the molecular mechanisms underlying ITH
Externí odkaz:
https://doaj.org/article/85edbdba6ed3490983b6962991638ed8
Autor:
Kohei Kumegawa, Yoko Takahashi, Sumito Saeki, Liying Yang, Tomoyoshi Nakadai, Tomo Osako, Seiichi Mori, Tetsuo Noda, Shinji Ohno, Takayuki Ueno, Reo Maruyama
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract In breast cancer patients, tumor heterogeneity is associated with prognosis and therapeutic response; however, the epigenetic diversity that exists in primary tumors remains unknown. Using a single-cell sequencing assay for transposase-acces
Externí odkaz:
https://doaj.org/article/f27c2438b17d40f492a2f03c6ce25442
Autor:
Yoshihiko Hosokawa, Sumiyo Okawa, Ai Hori, Naho Morisaki, Yoko Takahashi, Takeo Fujiwara, Shoji F. Nakayama, Hiromi Hamada, Toyomi Satoh, Takahiro Tabuchi
Publikováno v:
Journal of Epidemiology, Vol 32, Iss 4, Pp 188-194 (2022)
Background: Reluctance of people to receive recommended vaccines is a growing concern, as distribution of vaccines is considered critical to ending the COVID-19 pandemic. There is little information regarding pregnant women’s views toward coronavir
Externí odkaz:
https://doaj.org/article/adc806c9525d4b10978fd3c6aa35c7ee
Autor:
Mami Yokota, Yoshiyuki Kamiya, Tamie Suzuki, Shinsuke Ishikawa, Akira Takeda, Shinya Kondo, Takeshi Tohgasaki, Takuji Nakashima, Yoko Takahashi, Satoshi Ōmura, Tetsuhito Sakurai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Trehangelins (THG) are newly identified trehalose compounds derived from broth cultures of an endophytic actinomycete, Polymorphospora rubra. THG are known to suppress Cellular Communication Network factor 1 (CCN1), which regulates collagen
Externí odkaz:
https://doaj.org/article/297efae6831f4fcba9fa78ce028bf545