Výsledky vyhledávání - "Yoko, Hirakawa"

Altered Biodistribution and Hepatic Safety Profile of a Gapmer Antisense Oligonucleotide Bearing Guanidine-Bridged Nucleic Acids

Autor: Takashi Sasaki, Yoko Hirakawa, Fumiko Yamairi, Takashi Kurita, Karin Murahashi, Hirokazu Nishimura, Norihiko Iwazaki, Hidenori Yasuhara, Takashi Tateoka, Tetsuya Ohta, Satoshi Obika, Jun Kotera

Publikováno v: Nucleic acid therapeutics. 32(3)

Guanidine-bridged nucleic acid (GuNA) is a novel 2',4'-bridged nucleic acid/locked nucleic acid (2',4'-BNA/LNA) analog containing cations that exhibit strong affinity for target RNA and superior nuclease resistance. In this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d0cd122d69e3c02cbbee2d49e891be
https://pubmed.ncbi.nlm.nih.gov/35073217

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Intravascular hemolysis in patients with mitral regurgitation: Evaluation by erythrocyte creatine

Autor: Toshika Okumiya, Mikio Kamioka, Yoko Hirakawa, Yoshihisa Matsumura, Taisuke Hisahara, Tetsuro Sugiura, Toru Kubo

Publikováno v: Journal of Cardiology. 71:414-418

Background Intravascular hemolysis has been reported in patients with cardiac valve prostheses, but intravascular hemolysis in patients with mitral regurgitation with native valve has not been evaluated in detail. We designed a study to elucidate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6e5a9dcfe91cff3985b35b0355b3b5
https://doi.org/10.1016/j.jjcc.2017.10.006

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Relationship between matrix metalloproteinase-3 serum level and pulmonary artery systolic pressure in patients with rheumatoid arthritis

Autor: Taisuke Hisahara, Yoko Hirakawa, Mikio Kamioka, Yoshihisa Matsumura, Shigeo Yamanaka, Tetsuro Sugiura

Publikováno v: Heart and vessels. 33(2)

Activity of rheumatoid arthritis (RA) has been evaluated by various biomarkers including matrix metalloproteinase (MMP)-3, but the relationship between the levels of biomarkers and elevation of pulmonary artery systolic pressure (PAs) has not been ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff00fc9d7b9ada7e84947d4780304e3
https://pubmed.ncbi.nlm.nih.gov/28828748

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3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors prevent the progression of renal dysfunction in Japanese hypertensive patients

Autor: Yoko Hirakawa, Toru Kubo, Masanori Nishinaga, Kanji Bando, Masanori Kuwabara, Yoshinori Doi, Hiroaki Kitaoka

Publikováno v: Geriatrics & Gerontology International. 10:219-224

Aim: The aim was to determine whether the use of statins prevents the progression of chronic kidney disease (CKD) in hypertensive patients. Methods: We retrospectively reviewed data obtained from hypertensive patients, and subjects with diabetes mell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::380f58eb34097fcfc9df87d4b6a6aed2
https://doi.org/10.1111/j.1447-0594.2010.00584.x

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Establishment and Evaluation of Cancer-Specific Human Monoclonal Antibody GAH for Targeting Chemotherapy Using Immunoliposomes

Autor: Toshiaki Tagawa, Yoko Hirakawa, Kazuhiro Nagaike, Katsuhiko Nohga, Saiko Hosokawa, Hisae Niki, Norihiko Ito

Publikováno v: Hybridoma and Hybridomics. 23:109-120

To establish human monoclonal antibodies suitable for targeting chemotherapy, we prepared a panel of human-mouse hybridomas, using mouse myelomas and lymphocytes of regional lymph nodes excised from cancer patients, and selected antibodies on the bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4ac268161db0b47d95897a0a612511
https://doi.org/10.1089/153685904774129711

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3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors prevent the progression of renal dysfunction in Japanese hypertensive patients

Autor: Masanori, Kuwabara, Toru, Kubo, Kanji, Bando, Yoko, Hirakawa, Hiroaki, Kitaoka, Masanori, Nishinaga, Yoshinori L, Doi

Publikováno v: Geriatricsgerontology international. 10(3)

The aim was to determine whether the use of statins prevents the progression of chronic kidney disease (CKD) in hypertensive patients.We retrospectively reviewed data obtained from hypertensive patients, and subjects with diabetes mellitus and those

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23872c02e60f548188992ceece1639ae
https://pubmed.ncbi.nlm.nih.gov/20141537

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