Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yok Moi Khoo"'
Autor:
Cynthia Sung, Yuan Wei, Satoru Watanabe, How Sung Lee, Yok Moi Khoo, Lu Fan, Abhay P S Rathore, Kitti Wing-Ki Chan, Milly M Choy, Uma S Kamaraj, October M Sessions, Pauline Aw, Paola F de Sessions, Bernett Lee, John E Connolly, Martin L Hibberd, Dhanasekaran Vijaykrishna, Limin Wijaya, Eng Eong Ooi, Jenny Guek-Hong Low, Subhash G Vasudevan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004851 (2016)
UNLABELLED:CELADEN was a randomized placebo-controlled trial of 50 patients with confirmed dengue fever to evaluate the efficacy and safety of celgosivir (A study registered at ClinicalTrials.gov, number NCT01619969). Celgosivir was given as a 400 mg
Externí odkaz:
https://doaj.org/article/70f670966543435686197209b8c5a0f4
Autor:
Eng Eong Ooi, Satoru Watanabe, Jenny G. Low, How Sung Lee, John E. Connolly, Subhash G. Vasudevan, Cynthia Sung, Abhay P. S. Rathore, Fan Lu, Yok Moi Khoo
Publikováno v:
Antiviral Research. 96:32-35
Celgosivir (6-O-butanoyl castanospermine), a pro-drug of the naturally occurring castanospermine, is an inhibitor of α-glucosidase I and II that is found to be a potent inhibitor of several enveloped viruses including all four serotypes of dengue vi
Autor:
Eng Eong Ooi, How Sung Lee, Pauline Aw, John E. Connolly, Subhash G. Vasudevan, Uma S. Kamaraj, Milly M. Choy, Dhanasekaran Vijaykrishna, Yuan Wei, Satoru Watanabe, Limin Wijaya, Jenny G. Low, Paola Florez de Sessions, Lu Fan, Cynthia Sung, Bernett Lee, Abhay P. S. Rathore, October M. Sessions, Kitti Wing Ki Chan, Yok Moi Khoo, Martin L. Hibberd
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004851 (2016)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
CELADEN was a randomized placebo-controlled trial of 50 patients with confirmed dengue fever to evaluate the efficacy and safety of celgosivir (A study registered at ClinicalTrials.gov, number NCT01619969). Celgosivir was given as a 400 mg loading do
Publikováno v:
Therapeutic Drug Monitoring. 29:231-235
PXD101, a new histone deacetylase inhibitor, is currently undergoing phase I/II clinical trials as an anticancer drug. This study describes a simple and sensitive high-performance liquid chromatography ultraviolet method developed for the quantificat
Autor:
Ai Bee Ong, How Sung Lee, Boon Cher Goh, Lu Fan, Robert Lim, Charlotte Chua, Lingzhi Wang, Yok Moi Khoo
Publikováno v:
British Journal of Clinical Pharmacology. 55:270-277
Aims To investigate CYP3A activity in cancer and noncancer Asian patients using midazolam and to reveal possible alternative traits for phenotyping CYP3A. Methods Intravenous midazolam 2.5 mg or 2.5–8 mg was administered to 27 cancer and 24 noncanc
Publikováno v:
Rapid Communications in Mass Spectrometry. 17:1548-1552
A novel, rapid and sensitive isocratic liquid chromatography/tandem mass spectrometry (LC/MS/MS) method was developed for quantification of docetaxel in human plasma with paclitaxel as internal standard. The high sensitivity and specificity of MS/MS
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:2248-2251
Steady-state peak and trough concentrations of metronidazole and its metabolites were measured in the sera of 54 surgical patients who were on intravenous metronidazole, 500 mg every 8 h. These patients had no significant renal or hepatic impairment.
Publikováno v:
British Journal of Clinical Pharmacology. 41:41-47
1. Many pharmacokinetic studies on paracetamol are based on saliva paracetamol concentrations. The utility of saliva in patients with chronic renal failure is unclear. In this study, concentrations of saliva and plasma paracetamol and its major metab
Autor:
Agnes Suah-Bee Ng, Shani Sian-Wei Tan, Bee-Choo Chua, How Sung Lee, Sook-Leung Chew, Yok-Moi Khoo
Publikováno v:
Therapeutic Drug Monitoring. 17:336-341
The pharmacokinetics of propofol was studied in 11 Asian patients with fentanyl-isoflurane anaesthesia during cardiopulmonary bypass (CPB) and undergoing elective coronary artery bypass grafting (CABG). Instead of the usual increments of morphine and
Autor:
Jin-Song Bian, Lih-Wen Deng, Fei Hua, Matthew Whiteman, Qian Chen Yong, Jia Ling Cheong, Alexis Perry, How Sung Lee, Yok Moi Khoo, Mark E. Wood
Publikováno v:
Antioxidantsredox signaling. 14(11)
Both nitric oxide (NO) and hydrogen sulfide (H(2)S) are two important gaseous mediators regulating heart function. The present study examined the interaction between these two biological gases and its role in the heart. We found that l-arginine, a su