Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yoji Ikuina"'
Autor:
Sreenath V. Sharma, Junichi Kurebayashi, Shiro Akinaga, Yoji Ikuina, Leonard M. Neckers, Tatsuya Tamaoki, Yukimasa Shiotsu, Chikara Murakata, Harunobu Tahara, Theodor W. Schulte, Shiro Soga, Makiko Shimizu, Kazuo Yamaguchi
Publikováno v:
Cancer Chemotherapy and Pharmacology. 48:435-445
Purpose: Radicicol is a novel hsp90 antagonist, distinct from the chemically unrelated benzoquinone ansamycin compounds, geldanamycin and herbimycin. Both geldanamycin and radicicol bind in the aminoterminal nucleotide-binding pocket of hsp90, destab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83cd4cf140fc0b917ce62e04cf32c49
https://doi.org/10.1007/s002800100373
https://doi.org/10.1007/s002800100373
Autor:
Fumihiko Kanai, Shiro Akinaga, Hideaki Mizoguchi, Kinya Yamashita, Chikara Murakata, Yoji Ikuina, Tatsuya Tamaoki, Yukimasa Shiotsu, Masanao Teramura
Publikováno v:
Blood. 95:3771-3780
We examined the chemoprotective effects of KF41399, a novel derivative of carbazole compounds, on severe thrombocytopenia induced by nimustine (ACNU, 45 mg/kg administered for 2 consecutive days intravenously) in mice. Administration schedule studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5951503588b6d89516ce6ad05cb1221c
https://doi.org/10.1182/blood.v95.12.3771
https://doi.org/10.1182/blood.v95.12.3771
Autor:
Yutaka Saitoh, Yoji Ikuina, Satoshi Nakanishi, Hiroshi Yano, Katsuhiko Ando, Yuzuru Matsuda, Mayumi Yoshida
Publikováno v:
The Journal of Antibiotics. 50:992-997
Novel compounds MS-681a, b, c and d were isolated from the culture broth of a fungal strain KY6568. The strain was identified as Myrothecium sp. from its morphological characteristics. MS-681a, b, c and d inhibited the activity of purified smooth mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171008444c9e6116b1426f75e1388ac4
https://doi.org/10.7164/antibiotics.50.992
https://doi.org/10.7164/antibiotics.50.992
Autor:
Isao Kawamoto, Yoji Ikuina, Katsuhiko Ando, Kazutoshi Kuroda, Yuzuru Matsuda, Yoshikazu Morishita, Yutaka Saito
Publikováno v:
The Journal of Antibiotics. 47:16-22
AS-186a, b, c, d, and g were isolated from the cultured broth of Penicillium asperosporum KY1635 as inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT). IC50 values for the effect of AS-186a, b, c, d, and g against ACAT activity of the microso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154a05c8d8d473935504093a53b26aaf
https://doi.org/10.7164/antibiotics.47.16
https://doi.org/10.7164/antibiotics.47.16
Autor:
Yoshikazu Morishita, Katsuhiko Ando, Yuzuru Matsuda, Kazutoshi Kuroda, Yutaka Saito, Yoji Ikuina, Isao Kawamoto
Publikováno v:
ChemInform. 25
AS-186a, b, c, d, and g were isolated from the cultured broth of Penicillium asperosporum KY1635 as inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT). IC50 values for the effect of AS-186a, b, c, d, and g against ACAT activity of the microso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f159d240524697a73679cc806c9fd94
https://doi.org/10.1002/chin.199431281
https://doi.org/10.1002/chin.199431281
Autor:
Yoji Ikuina, Yoko Kanzawa, Katsumi Kakinuma, Yoshinori Fujimoto, Mitsuhiro Nagakari, Nobuo Ikekawa
Publikováno v:
Heterocycles. 30(No. 1):275-278
The mechanism of the BF 3 •etherate-catalyzed rearrangement of fucosterol benzoate 24,28-epoxide leading to desmosterol benzoate and two carbonyl compounds was investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d360f168141cb6c1d1303677c757bc61
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100400527
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100400527
Autor:
Tadakazu Akiyama, Yukimasa Shiotsu, Yoji Ikuina, Harumi Ogawa, Shiro Akinaga, Mayumi Miyata, Nobuyoshi Amishiro, Chikara Murakata, Hiroaki Narumi
Publikováno v:
Journal of medicinal chemistry. 46(12)
Radicicol (1), a macrocyclic antifungal antibiotic, is the lead compound of a novel class of heat shock protein 90 (Hsp90) inhibitors that result in the inhibition or degradation of Hsp90-associated proteins, such as v-src and Raf-1 kinases. New O-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9e6b740aa884411b4c709a0222360a
https://pubmed.ncbi.nlm.nih.gov/12773056
https://pubmed.ncbi.nlm.nih.gov/12773056
Publikováno v:
The Journal of antibiotics. 50(12)
MS-681a, b, c and d are new inhibitors of myosin light chain kinase produced by Myrothecium sp. They are novel octapeptides containing alpha-alkyl-alpha-amino acids and a polyamine moiety. The structures were determined by NMR and FAB-MS/MS spectral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30507a3483b7c0258304c8ab684924d4
https://pubmed.ncbi.nlm.nih.gov/9510905
https://pubmed.ncbi.nlm.nih.gov/9510905
Publikováno v:
ChemInform. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e78bf98308ef65e49d2f77d9ed04165e
https://doi.org/10.1002/chin.199042302
https://doi.org/10.1002/chin.199042302
Publikováno v:
J. Chem. Soc., Chem. Commun.. :688-689
The C-25 stereochemistry of the reaction catalysed by sterol-Δ24-reductase from the insect, B. mori, has been investigated by the use of 13C NMR spectroscopy; incubation of isopropylidene (E)-methyl-13C labelled desmosterol afforded cholesterol with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51d98edc4e413a597a72bdbc4674cb0
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100399748
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100399748