Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yoji Andrew Minamishima"'
Publikováno v:
Cancer Science. 114:1208-1217
Publikováno v:
The Journal of Biochemistry.
Sphingosine 1-phosphate (S1P) is one of the lipid mediators involved in diverse physiological functions. S1P circulates in blood and lymph bound to carrier proteins. Three S1P carrier proteins have been reported, albumin, apolipoprotein M (ApoM) and
Autor:
Yoji Andrew Minamishima, Makoto Suematsu, Hideyuki Saya, Ryo Fukuda, Takehiro Yamamoto, Noriyo Hayakawa, Yoshiko Nagahata, Tomomi Matsuura, Yuki Sugiura, Mitsuyo Ohmura, Akiko Kubo, Takako Hishiki, Kuniaki Mukai, Yan Bao
PDF - 1735K, Table S1: Percentages of Fucci-HTC116 in S + G2 and G1 phases in mouse liver metastatic foci. Table S2: Numbers of MALDO-IMS measurement points in mouse liver metastatic foci. Figure S1: Frequency distribution of relative intensities of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb53af9e9bf6b796683c04fde1e7d29
https://doi.org/10.1158/1541-7786.22509174.v1
https://doi.org/10.1158/1541-7786.22509174.v1
Autor:
Yoji Andrew Minamishima, Makoto Suematsu, Hideyuki Saya, Ryo Fukuda, Takehiro Yamamoto, Noriyo Hayakawa, Yoshiko Nagahata, Tomomi Matsuura, Yuki Sugiura, Mitsuyo Ohmura, Akiko Kubo, Takako Hishiki, Kuniaki Mukai, Yan Bao
Activation of aerobic glycolysis in cancer cells is well known as the Warburg effect, although its relation to cell- cycle progression remains unknown. In this study, human colon cancer cells were labeled with a cell-cycle phase-dependent fluorescent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73131d18bef596a417f3e538206412fe
https://doi.org/10.1158/1541-7786.c.6539217.v1
https://doi.org/10.1158/1541-7786.c.6539217.v1
Autor:
Takashi Izumi, Chiaki Fujita, Yoji Andrew Minamishima, Binderiya Tserendavga, Mari Ohshima, Koji Yuzawa, Noriyuki Yanaka, Noriyasu Ohshima
Publikováno v:
The Journal of Biochemistry. 170:713-727
GDE4 and GDE7 are membrane-bound enzymes that exhibit lysophospholipase D activities. We found that GDE7 produced not only lysophosphatidic acid (LPA) but also cyclic phosphatidic acid (cPA) from lysophospholipids by a transphosphatidylation reaction
Autor:
Xian Zhao, Keisuke Kiyozuka, Akimitsu Konishi, Reika Kawabata-Iwakawa, Yoji Andrew Minamishima, Hideru Obinata
Publikováno v:
Journal of Biological Chemistry. :104851
Autor:
Yoji Andrew Minamishima
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 155(1)
Hypoxic responses are mainly regulated by heterodimeric transcription factor HIF, composed of unstable α-subunit (HIFα) and stable β-subunit (HIF1β/ARNT). Protein stability of HIFα depends on the hydroxylation status of its specific proline resi
Autor:
Naohiro Takahashi, Tomokazu Okado, Hiroaki Kikuchi, Fumiaki Ando, Yoji Andrew Minamishima, Takahiro Yamashita, Naohiro Nomura, Eisei Sohara, Takayasu Mori, Shintaro Mandai, Yasuhiro Maejima, Tatemitsu Rai, Shinichi Uchida, Kiyoshi Isobe, Yohei Arai, Taisuke Furusho, Emi Sasaki, Yuki Yoshizaki
Publikováno v:
Kidney international. 95(1)
The kidneys consume a large amount of energy to regulate volume status and blood pressure and to excrete uremic toxins. The identification of factors that cause energy mismatch in the setting of chronic kidney disease (CKD) and the development of int
Autor:
Tomoko Oyaizu, Takako Hishiki, Tsuyoshi Nakanishi, Tomohiro Suhara, Noriyo Hayakawa, Masataka Kasahara, Makoto Suematsu, Akiko Kubo, William G. Kaelin, Yoji Andrew Minamishima, Hiroshi Morisaki
Publikováno v:
Proceedings of the National Academy of Sciences. 112:11642-11647
Loss of prolyl hydroxylase 2 (PHD2) activates the hypoxia-inducible factor-dependent hypoxic response, including anaerobic glycolysis, which causes large amounts of lactate to be released from cells into the circulation. We found that Phd2-null mouse
Autor:
Akiko Kubo, Kyoji Yamaguchi, Tomohiro Suhara, Tomoko Oyaizu-Toramaru, Takako Hishiki, Hiroshi Morisaki, Makoto Suematsu, Takashi Nakamura, Noriyo Hayakawa, Shizuka Minamishima, Yoji Andrew Minamishima
Publikováno v:
Molecular and cellular biology. 37(16)
Metformin is one of the most widely used therapeutics for type 2 diabetes mellitus and also has anticancer and antiaging properties. However, it is known to induce metformin-associated lactic acidosis (MALA), a severe medical condition with poor prog