Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yoichiro Shiba"'
Publikováno v:
AMB Express
A fungus, Thelonectria discophora SANK 18292 (JCM 30947), produces nectrisine that has a nitrogen-containing heterocyclic 5-membered ring acting as a glycosidase inhibitor. Our previous study showed the possibility that 4-amino-4-deoxyarabinitol was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdab3194779e1c8526b7817d2d496b7
https://doi.org/10.1186/s13568-016-0176-1
https://doi.org/10.1186/s13568-016-0176-1
Autor:
Ryuki MIYAUCHI, Yoichiro SHIBA
Publikováno v:
KAGAKU TO SEIBUTSU. 55:161-162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35fe624ce87f10be19e14434ad95fe83
https://doi.org/10.1271/kagakutoseibutsu.55.161
https://doi.org/10.1271/kagakutoseibutsu.55.161
Publikováno v:
Metabolic Engineering. 9:160-168
Amorphadiene, a sesquiterpene precursor to the anti-malarial drug artemisinin, is synthesized by the cyclization of farnesyl pyrophosphate (FPP). Saccharomyces cerevisiae produces FPP through the mevalonate pathway using acetyl-CoA as a starting comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a64555eb0fc6d534ddc6119a0529e80
https://doi.org/10.1016/j.ymben.2006.10.005
https://doi.org/10.1016/j.ymben.2006.10.005
Publikováno v:
Phytochemistry. 116
Nectrisine, an iminosugar with a heterocyclic nitrogen-containing 5-membered ring, acts as a glycosidase inhibitor. Thelonectria discophora SANK 18292, a fungus, was identified as a nectrisine producer from its microbial library in our screening for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991a3b643f3a287819216a591af07868
https://pubmed.ncbi.nlm.nih.gov/25865736
https://pubmed.ncbi.nlm.nih.gov/25865736
Autor:
Fumio Fukui, Katsuya Gomi, Yoichiro Shiba, Nobufusa Serizawa, Hiroji Yoshikawa, Chiho Ono, Ichiro Watanabe
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 65:94-101
Phospholipase A1 (PLA1) is a hydrolytic enzyme that catalyzes the removal of the acyl group from position 1 of lecithin to form lysolecithin. The PLA1 gene, which had been cloned from Aspergillus oryzae, was expressed in Saccharomyces cerevisiae and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa926c71a9860edc8ae31f20f08c3555
https://doi.org/10.1271/bbb.65.94
https://doi.org/10.1271/bbb.65.94
Publikováno v:
Journal of Bioscience and Bioengineering. 89:426-430
In the course of studying carboxypeptidase Y (CPY) production, we found that the expression level of the gene, which is under the control of the GAL10 promoter, increased in a Saccharomyces cerevisiae gal80 mutant grown in a medium containing ethanol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f0cc3d7cb7024e80aff4c5dce0a3cd
https://doi.org/10.1016/s1389-1723(00)89091-x
https://doi.org/10.1016/s1389-1723(00)89091-x
Publikováno v:
Journal of Fermentation and Bioengineering. 86:545-549
Carboxypeptidase Y (CPY; EC 3. 4. 16. 1) encoded by the PRC1 gene is a yeast vacuolar protease. It enters the vacuole as a zymogen, proCPY, which is activated by vacuolar enzymes, proteinase A (PrA) and proteinase B (PrB). We previously showed that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::720cdb2fe75b789f62f7881f7fe2a2e6
https://doi.org/10.1016/s0922-338x(99)80004-x
https://doi.org/10.1016/s0922-338x(99)80004-x
Publikováno v:
Journal of Bioscience and Bioengineering. 90:470-472
A method for industrial-scale preparation of carboxypeptidase Y (CPY), which was secreted by Saccharomyces cerevisiae KS58-2D/pCY303 into the culture broth, was developed. Because the purification process consists of a few simple unit operations incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc19d1a04f8a2d72e1e5f64f02813b3
https://doi.org/10.1263/jbb.90.470
https://doi.org/10.1263/jbb.90.470
Autor:
Dae-Kyun Ro, Eric M. Paradise, John M. Ndungu, James Kirby, Richmond Sarpong, Mario Ouellet, Timothy S. Ham, Ho Kimberly, Karl Fisher, Michelle C. Y. Chang, Karyn L. Newman, Eachus Rachel, Yoichiro Shiba, Sydnor T. Withers, Jay D. Keasling
Publikováno v:
Nature. 440(7086)
Drug-resistant strains of the malaria parasite are widespread, and as a result mortality due to malaria has increased significantly in recent years. Artemisinin, isolated from the herb Artemisia annua (sweet wormwood), is one drug that shows a high e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fe888ba20f57c7310dc577ce8cc683
https://pubmed.ncbi.nlm.nih.gov/16612346
https://pubmed.ncbi.nlm.nih.gov/16612346
Publikováno v:
Bioscience, biotechnology, and biochemistry. 63(8)
The production level of CPY in Saccharomyces cerevisiae KS58-2D/pCY303 was drastically decreased when thiamine was not added to the culture medium. We isolated and characterized the mutants that could produce CPY even though thiamine was absent from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aaa93899128905611a0158af5316060
https://pubmed.ncbi.nlm.nih.gov/10501001
https://pubmed.ncbi.nlm.nih.gov/10501001