Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Yoichiro Kusakari"'
Autor:
Kazuhiro Kuga, Yoichiro Kusakari, Ken Uesugi, Kentaro Semba, Takashi Urashima, Toru Akaike, Susumu Minamisawa
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231905 (2020)
Myocardial fibrosis is often associated with cardiac hypertrophy; indeed, fibrosis is one of the most critical factors affecting prognosis. We aimed to identify the molecules involved in promoting fibrosis under hypertrophic stimuli. We previously es
Externí odkaz:
https://doaj.org/article/e064458f725645a9aba63650a369a1ce
Autor:
Yoichiro Kusakari, Takashi Urashima, Daisuke Shimura, Erika Amemiya, Genki Miyasaka, Shunsuke Yokota, Yoshitaka Fujimoto, Toru Akaike, Takahiro Inoue, Susumu Minamisawa
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169564 (2017)
Interstitial myocardial fibrosis is one of the factors responsible for dysfunction of the heart. However, how interstitial fibrosis affects cardiac function and excitation-contraction coupling (E-C coupling) has not yet been clarified. We developed a
Externí odkaz:
https://doaj.org/article/0af6335c3e7a42c69bb60fc8f4108a91
Autor:
Yoshitaka Fujimoto, Takashi Urashima, Daisuke Shimura, Reiji Ito, Sadataka Kawachi, Ichige Kajimura, Toru Akaike, Yoichiro Kusakari, Masako Fujiwara, Kiyoshi Ogawa, Nobuhito Goda, Hiroyuki Ida, Susumu Minamisawa
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148666 (2016)
BACKGROUND:Hepatic fibrosis progresses with right heart failure, and becomes cardiac cirrhosis in a severe case. Although its causal factor still remains unclear. Here we evaluated the progression of hepatic fibrosis using a pulmonary artery banding
Externí odkaz:
https://doaj.org/article/91d85b372bbc4a8eb84c7587a2ca18c9
Autor:
Peng Zhang, Kara Ford, Jae Hwi Sung, Jacob Moeller, Yuta Suzuki, Iuliia Polina, Toshiaki Tachibana, Yoichiro Kusakari, Michael W Cypress, Isabel Chaput, Kamelia Drenkova, Maria Landherr, Stephanie M Adaniya, Jyotsna Mishra, Ulrike Mende, Bong Sook Jhun, Jin O-Uchi
Contact sites between the mitochondria and endoplasmic reticulum (ER) are irregulates the exchange of lipids, Ca2+, and reactive oxygen species (ROS) across the two organelles. Mitofusin 2 (Mfn2) has been shown as one of the major components tetherin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdb191a94eb95d2a80587c83113fd4e7
https://doi.org/10.1101/2022.02.21.481295
https://doi.org/10.1101/2022.02.21.481295
Autor:
Jessica L. Cao, Jin O-Uchi, Yuta Suzuki, Stephanie M. Adaniya, Bong Sook Jhun, Yoichiro Kusakari, Michael W. Cypress
Publikováno v:
Archives of Biochemistry and Biophysics. 663:276-287
Recent discoveries of the molecular identity of mitochondrial Ca(2+) influx/efflux mechanisms have placed mitochondrial Ca(2+) transport at center stage in views of cellular regulation in various cell-types/tissues. Indeed, mitochondria in cardiac mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656b903e3addb774436082f0b91bdc85
https://doi.org/10.1016/j.abb.2019.01.027
https://doi.org/10.1016/j.abb.2019.01.027
Autor:
Toru Akaike, Susumu Minamisawa, Yoichiro Kusakari, Ken Uesugi, Kazuhiro Kuga, Takashi Urashima, Kentaro Semba
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231905 (2020)
PLoS ONE
PLoS ONE
Myocardial fibrosis is often associated with cardiac hypertrophy; indeed, fibrosis is one of the most critical factors affecting prognosis. We aimed to identify the molecules involved in promoting fibrosis under hypertrophic stimuli. We previously es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489b1aec6ad21081e6cdbc71218df52d
https://doaj.org/article/e064458f725645a9aba63650a369a1ce
https://doaj.org/article/e064458f725645a9aba63650a369a1ce
Autor:
Yuki Yamada, Yoichiro Kusakari, Munetoshi Akaoka, Masato Watanabe, Jun Tanihata, Naritomo Nishioka, Hiroki Bochimoto, Toru Akaike, Toshiaki Tachibana, Susumu Minamisawa
Publikováno v:
Journal of Applied Physiology; Jan2021, Vol. 130 Issue 1, p26-35, 10p
Publikováno v:
Circulation Research. 125
Introduction: The effect of acute ventricular volume overload on organelles such as myofibrils and mitochondria are incompletely understood. Purpose: We performed acute overstretch on cardiac papillary muscle to investigate the functional and morphol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::319ef389f99659bceb314486462be67f
https://doi.org/10.1161/res.125.suppl_1.861
https://doi.org/10.1161/res.125.suppl_1.861
Autor:
Akiko Onda, Yasuhiro Sawada, Qibin Jiao, Yoichiro Kusakari, Susumu Minamisawa, Takayuki Akimoto, Toru Fukubayashi, Hajime Kono, Katsuhiko Suzuki, Toshikazu Miyamoto
Publikováno v:
Muscle & Nerve. 54:788-791
Introduction Disuse-induced skeletal muscle atrophy is a serious concern; however, there is not an effective mouse model to elucidate the molecular mechanisms. We developed a noninvasive atrophy model in mice. Methods After the ankle joints of mice w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b792c58cd8216dade0deeadb8ed722f
https://doi.org/10.1002/mus.25202
https://doi.org/10.1002/mus.25202
Autor:
Qibin Jiao, Gaku Nakai, Atsushi Nakano, Meihua Jin, Yoshihiro Ishikawa, Daisuke Shimura, Tomohiro Yokota, Yoichiro Kusakari, Nobuhito Goda, Tetsuo Sasano, Susumu Minamisawa, Yasuhiro Nakashima
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H92-H103
Sarcolipin (SLN) is a small proteolipid and a regulator of sarco(endo)plasmic reticulum Ca2+-ATPase. In heart tissue, SLN is exclusively expressed in the atrium. Previously, we inserted Cre recombinase into the endogenous SLN locus by homologous reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7d447fcb021e94d98be8a3cdeeec54
https://doi.org/10.1152/ajpheart.00411.2015
https://doi.org/10.1152/ajpheart.00411.2015