Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Yoichiro, Kakugawa"'
Autor:
Yuko Minami, Seiki Kanemura, Jun Kusaka, Makoto Kinouchi, Shinichi Suzuki, Hajime Iwasashi, Yoshikazu Nishino, Yoichiro Kakugawa, Koh Miura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract It has been postulated that being breastfed in infancy affects not only health status in childhood but also disease risk in adulthood. To investigate the association of being breastfed with the risks of adult colorectal cancer and benign tum
Externí odkaz:
https://doaj.org/article/c7423326f6d94d78978eaec34c80997d
Autor:
Kohsuke Gonda, Mika Watanabe, Hiroshi Tada, Minoru Miyashita, Yayoi Takahashi-Aoyama, Takashi Kamei, Takanori Ishida, Shin Usami, Hisashi Hirakawa, Yoichiro Kakugawa, Yohei Hamanaka, Ryuichi Yoshida, Akihiko Furuta, Hisatake Okada, Hideki Goda, Hiroshi Negishi, Kensaku Takanashi, Masaru Takahashi, Yuichi Ozaki, Yuka Yoshihara, Yasushi Nakano, Noriaki Ohuchi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The quantitative sensitivity and dynamic range of conventional immunohistochemistry (IHC) with 3,3′-diaminobenzidine (IHC-DAB) used in pathological diagnosis in hospitals are poor, because enzyme activity can affect the IHC-DAB chromogenic
Externí odkaz:
https://doaj.org/article/032c680d6f0045e89e611e90cded6e1d
Autor:
Yuko Minami, Seiki Kanemura, Masaaki Kawai, Yoshikazu Nishino, Hiroshi Tada, Minoru Miyashita, Takanori Ishida, Yoichiro Kakugawa
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224797 (2019)
BackgroundIt is unclear whether alcohol consumption may impact survival after breast cancer diagnosis. To clarify the association between pretreatment alcohol consumption and survival in breast cancer patients, a prospective patient cohort study was
Externí odkaz:
https://doaj.org/article/b5276b733940428489da3640f7c84a97
Autor:
Tadashi Nomizu, Takafumi Fukui, Yoichiro Kakugawa, Fumisyoshi Fujishima, Noriaki Ohuchi, Chikashi Ishioka, Takanori Ishida, Shin Takahashi
Publikováno v:
Breast Cancer (Tokyo, Japan)
Background TP53 status based on TP53 signature, a gene expression profile to determine the presence or absence of TP53 mutation, is an independent prognostic factor of breast cancer. The purpose of this study was to develop a simple diagnostic system
Autor:
Hiroshi Shima, Koh Miura, Miyuki Nomura, Honami Ogoh, Koreyuki Kurosawa, Kosuke Kanazawa, Yoichiro Kakugawa, Yui Inoue, Hidekazu Yamada, Natsuko Chiba, Ikuro Sato, Yoji Yamashita, Toshio Watanabe, Nobuhiro Tanuma, Yuki Momoi, Mai Suzuki, Kazuhiro Kishimoto, Masahiro Tachi
Publikováno v:
Cancer Science. 109:2178-2187
Here, we address the function of protein phosphatase 6 (PP6) loss on K-ras-initiated tumorigenesis in keratinocytes. To do so, we developed tamoxifen-inducible double mutant (K-rasG12D -expressing and Ppp6c-deficient) mice in which K-rasG12D expressi
Autor:
Seiki Kanemura, Koh Miura, Shinichi Suzuki, Tsuneaki Fujiya, Yasuhiro Hasegawa, Yuko Minami, Yoshikazu Nishino, Tomoyuki Oikawa, Yoichiro Kakugawa
Publikováno v:
International Journal of Cancer. 143:1072-1085
Cigarette smoking and alcohol drinking may affect the prognosis of stomach cancer, but evidence has been inconsistent. We investigated the associations between pretreatment smoking and alcohol drinking and the risk of all-cause and stomach cancer dea
Autor:
Tadashi Nomizu, Shin Takahashi, Yoichiro Kakugawa, Shigeo Yamaguchi, Yuki Izumi, Chikashi Ishioka, Yumi Nozaki, Kaoru Mogushi, Noriaki Ohuchi, Shunsuke Kato, Takanori Ishida
Publikováno v:
Oncotarget. 9:14193-14206
// Shigeo Yamaguchi 1 , Shin Takahashi 2 , Kaoru Mogushi 3 , Yuki Izumi 1 , Yumi Nozaki 1 , Tadashi Nomizu 4 , Yoichiro Kakugawa 5 , Takanori Ishida 6 , Noriaki Ohuchi 6 , Chikashi Ishioka 2 and Shunsuke Kato 1, 3 1 Department of Clinical Oncology, J
Autor:
Yoichiro Kakugawa, Yoko Takizawa, Noriaki Ohuchi, Yuko Minami, Masaaki Kawai, Yoshikazu Nishino
Publikováno v:
The Tohoku Journal of Experimental Medicine. 244:63-73
Alcohol consumption is a risk factor for breast cancer in Western countries, but few studies have evaluated the risk for Japanese women, who have a relatively low alcohol intake. This case-control study investigated the association of alcohol consump
Autor:
Masaaki Kawai, Yasuhiro Hasegawa, Kuniharu Yamamoto, Naoko Takebe, Makoto Kinouchi, Kousuke Kanazawa, Masayuki Satoh, Ryuichi Katakura, Michiaki Unno, Kennichi Satoh, Koh Miura, Hiroshi Shima, Julie K. Rhie, Yoichiro Kakugawa, Tsuneaki Fujiya
Publikováno v:
Expert Opinion on Drug Delivery. 14:1355-1366
Sixty years since its introduction, 5-FU still forms the core of chemotherapy regimens for many types of malignancies. 5-FU is a time-dependent drug but is rapidly degraded in plasma by dihydropyrimidine dehydrogenase (DPD). Although originally devel
Autor:
Minoru Miyashita, Yoshikazu Nishino, Masaaki Kawai, Seiki Kanemura, Yuko Minami, Yoichiro Kakugawa, Takanori Ishida, Hiroshi Tada
Publikováno v:
Breast cancer (Tokyo, Japan). 26(6)
Reproductive factors may influence breast cancer progression and patient survival; however, evidence has been limited. The associations of reproductive factors with tumor characteristics and patient survival were analyzed among 1468 breast cancer pat