Zobrazeno 1 - 10
of 929
pro vyhledávání: '"Yoichiro, Iwakura"'
Autor:
Shuto Tanaka, Masataka Kawakita, Hikaru Yasui, Koichi Sudo, Fumie Itoh, Masato Sasaki, Nobuyuki Shibata, Hiromitsu Hara, Yoichiro Iwakura, Tomomi Hashidate-Yoshida, Hideo Shindou, Takao Shimizu, Taiki Oyama, Himawari Matsunaga, Kazuhiko Takahara
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract Acute immune responses with excess production of cytokines, lipid/chemical mediators, or coagulation factors, often result in lethal damage. In addition, the innate immune system utilizes multiple types of receptors that recognize neurotrans
Externí odkaz:
https://doaj.org/article/1ce32dd6b57e4157970de60655be50fa
Autor:
Naoto Yoshimura, Ryusho Kariya, Masaki Shimada, Makoto Tateyama, Hideto Matsunaga, Yuto Shibata, Shuntaro Tanimura, Kosei Takata, Takahiro Arima, Junki Kawakami, Kazuya Maeda, Yuko Fukuma, Masaru Uragami, Katsumasa Ideo, Kazuki Sugimoto, Ryuji Yonemitsu, Kozo Matsushita, Satoshi Hisanaga, Masaki Yugami, Yusuke Uehara, Tetsuro Masuda, Takayuki Nakamura, Takuya Tokunaga, Tatsuki Karasugi, Takanao Sueyoshi, Hiro Sato, Yoichiro Iwakura, Kimi Araki, Eisuke Kobayashi, Seiji Okada, Takeshi Miyamoto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Osteosarcoma is rare but is the most common bone tumor. Diagnostic tools such as magnetic resonance imaging development of chemotherapeutic agents have increased the survival rate in osteosarcoma patients, although 5-year survival has platea
Externí odkaz:
https://doaj.org/article/ed559e9c0ee0472ab0240adfebdfaea7
Autor:
Ce Tang, Haiyang Sun, Motohiko Kadoki, Wei Han, Xiaoqi Ye, Yulia Makusheva, Jianping Deng, Bingbing Feng, Ding Qiu, Ying Tan, Xinying Wang, Zehao Guo, Chanyan Huang, Sui Peng, Minhu Chen, Yoshiyuki Adachi, Naohito Ohno, Sergio Trombetta, Yoichiro Iwakura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
The effect of β-glucans and their receptor Dectin-1 in tumor development remains controversial. Here the authors show that Dectin-1 signaling promotes the development of colorectal cancer (CRC) by inducing prostaglandin E2 production in myeloid-deri
Externí odkaz:
https://doaj.org/article/ac5a7567c27846ed934a829b63683efa
Autor:
Toshihiko Suzuki, Kotchakorn Boonyaleka, Tokuju Okano, Tamako Iida, Mitsunori Yoshida, Hanako Fukano, Yoshihiko Hoshino, Yoichiro Iwakura, Anthony S. Ablordey, Hiroshi Ashida
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/76e75e34ff6343f495b41b26b8d7d929
Autor:
Zhengping Huang, Xiaomeng You, Liang Chen, Yan Du, Kailey Brodeur, Hyuk Jee, Qiang Wang, Grace Linder, Roxane Darbousset, Pierre Cunin, Margaret H. Chang, Alexandra Wactor, Brian M. Wauford, Marc J. C. Todd, Kevin Wei, Ying Li, Anais Levescot, Yoichiro Iwakura, Virginia Pascual, Nicole E. Baldwin, Pierre Quartier, Tianwang Li, Maria T. Gianatasio, Robert P. Hasserjian, Lauren A. Henderson, David B. Sykes, Elizabeth D. Mellins, Scott W. Canna, Julia F. Charles, Peter A. Nigrovic, Pui Y. Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Still’s disease is an inflammatory syndrome linked to the development of further immune dysregulation and hypercytokinaemia termed macrophage activation syndrome. Here the authors implicate the mechanistic target of rapamycin complex 1 in murine mo
Externí odkaz:
https://doaj.org/article/0b6c3e1af33b4a6dbc1260fdb044deab
Autor:
Tomonori Kaifu, Takumi Maruhashi, Soo-Hyun Chung, Kenji Shimizu, Akira Nakamura, Yoichiro Iwakura
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Dendritic cell immunoreceptor (DCIR) is an inhibitory C-type lectin receptor that acts as a negative regulator in the immune system and bone metabolism. We previously revealed that DCIR deficiency enhanced osteoclastogenesis and antigen presentation
Externí odkaz:
https://doaj.org/article/abeeffd923b04c9b8238870d97abdd04
Autor:
Chunfu Yang, Lei Lei, John W. Marshall Collins, Michael Briones, Li Ma, Gail L. Sturdevant, Hua Su, Anuj K. Kashyap, David Dorward, Kevin W. Bock, Ian N. Moore, Christine Bonner, Chih-Yu Chen, Craig A. Martens, Stacy Ricklefs, Masahiro Yamamoto, Kiyoshi Takeda, Yoichiro Iwakura, Grant McClarty, Harlan D. Caldwell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Myeloid cells are implicated in the innate immune and inflammatory response during infection with Chlamydia trachomatis. Here the authors show the evasion of the neutrophil response to infection and concomitant induction of sterile immunity via the p
Externí odkaz:
https://doaj.org/article/9b6d6afc6d5a40fdb29b81834b7b8934
Autor:
Rebecca A. Drummond, Jigar V. Desai, Amy P. Hsu, Vasileios Oikonomou, Donald C. Vinh, Joshua A. Acklin, Michael S. Abers, Magdalena A. Walkiewicz, Sarah L. Anzick, Muthulekha Swamydas, Simon Vautier, Mukil Natarajan, Andrew J. Oler, Daisuke Yamanaka, Katrin D. Mayer-Barber, Yoichiro Iwakura, David Bianchi, Brian Driscoll, Ken Hauck, Ahnika Kline, Nicholas S.P. Viall, Christa S. Zerbe, Elise M.N. Ferré, Monica M. Schmitt, Tom DiMaggio, Stefania Pittaluga, John A. Butman, Adrian M. Zelazny, Yvonne R. Shea, Cesar A. Arias, Cameron Ashbaugh, Maryam Mahmood, Zelalem Temesgen, Alexander G. Theofiles, Masayuki Nigo, Varsha Moudgal, Karen C. Bloch, Sean G. Kelly, M. Suzanne Whitworth, Ganesh Rao, Cindy J. Whitener, Neema Mafi, Juan Gea-Banacloche, Lawrence C. Kenyon, William R. Miller, Katia Boggian, Andrea Gilbert, Matthew Sincock, Alexandra F. Freeman, John E. Bennett, Rodrigo Hasbun, Constantinos M. Mikelis, Kyung J. Kwon-Chung, Yasmine Belkaid, Gordon D. Brown, Jean K. Lim, Douglas B. Kuhns, Steven M. Holland, Michail S. Lionakis
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Subcutaneous phaeohyphomycosis typically affects immunocompetent individuals following traumatic inoculation. Severe or disseminated infection can occur in CARD9 deficiency or after transplantation, but the mechanisms protecting against phaeohyphomyc
Externí odkaz:
https://doaj.org/article/71c653dd808145c48e7e7ce5ab2b01ae
Autor:
Anne-Charlotte Jonckheere, Sven F. Seys, Brecht Steelant, Tatjana Decaesteker, Kaat Dekoster, Jonathan Cremer, Ellen Dilissen, Dominique Schols, Yoichiro Iwakura, Greetje Vande Velde, Christine Breynaert, Rik Schrijvers, Jeroen Vanoirbeek, Jan L. Ceuppens, Lieven J. Dupont, Dominique M. A. Bullens
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/0ec3806632074fb880d27f00217ad2c1
Autor:
Rita Lippai, Apor Veres-Székely, Erna Sziksz, Yoichiro Iwakura, Domonkos Pap, Réka Rokonay, Beáta Szebeni, Gábor Lotz, Nóra J. Béres, Áron Cseh, Attila J. Szabó, Ádám Vannay
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Recently the role of Parkinson’s disease 7 (PARK7) was studied in gastrointestinal diseases, however, the complex role of PARK7 in the intestinal inflammation is still not completely clear. Expression and localization of PARK7 were determi
Externí odkaz:
https://doaj.org/article/8524719dc8ea4121b6f38ca873d01438