Zobrazeno 1 - 10
of 463
pro vyhledávání: '"Yoichi Suzuki"'
Autor:
Mika Sakurai-Yageta, Yoichi Suzuki
Publikováno v:
Nutrients, Vol 16, Iss 15, p 2444 (2024)
Biotin, also known as vitamin B7 or vitamin H, is a water-soluble B-complex vitamin and serves as an essential co-enzyme for five specific carboxylases. Holocarboxylase synthase (HCS) activates biotin and facilitates its covalent attachment to these
Externí odkaz:
https://doaj.org/article/81611e9739534c8186c9afdd0d324a6d
Autor:
Tomoharu Tokutomi, Akiko Yoshida, Akimune Fukushima, Kayono Yamamoto, Yasushi Ishigaki, Hiroshi Kawame, Nobuo Fuse, Fuji Nagami, Yoichi Suzuki, Mika Sakurai-Yageta, Akira Uruno, Kichiya Suzuki, Kozo Tanno, Hideki Ohmomo, Atsushi Shimizu, Masayuki Yamamoto, Makoto Sasaki
Publikováno v:
Genes, Vol 15, Iss 3, p 384 (2024)
Genetic testing is key in modern healthcare, particularly for monogenic disorders such as familial hypercholesterolemia. This Tohoku Medical Megabank Project study explored the impact of first-degree relatives’ dyslipidemia history on individual re
Externí odkaz:
https://doaj.org/article/6d92590006e14e42862b546f9efbdaeb
Autor:
Junichi Sugawara, Mami Ishikuro, Taku Obara, Tomomi Onuma, Keiko Murakami, Masahiro Kikuya, Fumihiko Ueno, Aoi Noda, Satoshi Mizuno, Tomoko Kobayashi, Yohei Hamanaka, Kichiya Suzuki, Eiichi Kodama, Naho Tsuchiya, Akira Uruno, Yoichi Suzuki, Osamu Tanabe, Hideyasu Kiyomoto, Akito Tsuboi, Atsushi Shimizu, Seizo Koshiba, Naoko Minegishi, Soichi Ogishima, Gen Tamiya, Hirohito Metoki, Atsushi Hozawa, Nobuo Fuse, Kengo Kinoshita, Shigeo Kure, Nobuo Yaegashi, Shinichi Kuriyama, Masayuki Yamamoto
Publikováno v:
Journal of Epidemiology, Vol 32, Iss 2, Pp 69-79 (2022)
Background: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study was launched in 2013 to evaluate the complex interactions of genetic and environmental factors in multifactorial diseases. The present study describes the materna
Externí odkaz:
https://doaj.org/article/29f115b3570c4e88a64d6eda3975ac8b
Autor:
Atsushi Hozawa, Kozo Tanno, Naoki Nakaya, Tomohiro Nakamura, Naho Tsuchiya, Takumi Hirata, Akira Narita, Mana Kogure, Kotaro Nochioka, Ryohei Sasaki, Nobuyuki Takanashi, Kotaro Otsuka, Kiyomi Sakata, Shinichi Kuriyama, Masahiro Kikuya, Osamu Tanabe, Junichi Sugawara, Kichiya Suzuki, Yoichi Suzuki, Eiichi N Kodama, Nobuo Fuse, Hideyasu Kiyomoto, Hiroaki Tomita, Akira Uruno, Yohei Hamanaka, Hirohito Metoki, Mami Ishikuro, Taku Obara, Tomoko Kobayashi, Kazuyuki Kitatani, Takako Takai-Igarashi, Soichi Ogishima, Mamoru Satoh, Hideki Ohmomo, Akito Tsuboi, Shinichi Egawa, Tadashi Ishii, Kiyoshi Ito, Sadayoshi Ito, Yasuyuki Taki, Naoko Minegishi, Naoto Ishii, Masao Nagasaki, Kazuhiko Igarashi, Seizo Koshiba, Ritsuko Shimizu, Gen Tamiya, Keiko Nakayama, Hozumi Motohashi, Jun Yasuda, Atsushi Shimizu, Tsuyoshi Hachiya, Yuh Shiwa, Teiji Tominaga, Hiroshi Tanaka, Kotaro Oyama, Ryoichi Tanaka, Hiroshi Kawame, Akimune Fukushima, Yasushi Ishigaki, Tomoharu Tokutomi, Noriko Osumi, Tadao Kobayashi, Fuji Nagami, Hiroaki Hashizume, Tomohiko Arai, Yoshio Kawaguchi, Shinichi Higuchi, Masaki Sakaida, Ryujin Endo, Satoshi Nishizuka, Ichiro Tsuji, Jiro Hitomi, Motoyuki Nakamura, Kuniaki Ogasawara, Nobuo Yaegashi, Kengo Kinoshita, Shigeo Kure, Akio Sakai, Seiichiro Kobayashi, Kenji Sobue, Makoto Sasaki, Masayuki Yamamoto
Publikováno v:
Journal of Epidemiology, Vol 31, Iss 1, Pp 65-76 (2021)
Background: We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular di
Externí odkaz:
https://doaj.org/article/64f92cd82beb4bfabc4ed85922f051b4
Autor:
Nobuo Fuse, MD, PhD, Miyuki Sakurai, PhD, Ikuko N. Motoike, PhD, Kaname Kojima, PhD, Takako Takai-Igarashi, PhD, Naoki Nakaya, PhD, Naho Tsuchiya, MD, PhD, Tomohiro Nakamura, PhD, Mami Ishikuro, PhD, Taku Obara, PhD, Akiko Miyazawa, MD, PhD, Kei Homma, MD, PhD, Keisuke Ido, PhD, Makiko Taira, MD, PhD, Tomoko Kobayashi, MD, PhD, Ritsuko Shimizu, MD, PhD, Akira Uruno, MD, PhD, Eiichi N. Kodama, MD, PhD, Kichiya Suzuki, MD, PhD, Yohei Hamanaka, MD, PhD, Hiroaki Tomita, MD, PhD, Junichi Sugawara, MD, PhD, Yoichi Suzuki, MD, PhD, Fuji Nagami, PhD, Soichi Ogishima, PhD, Fumiki Katsuoka, PhD, Naoko Minegishi, MD, PhD, Atsushi Hozawa, MD, PhD, Shinichi Kuriyama, MD, PhD, Nobuo Yaegashi, MD, PhD, Shigeo Kure, MD, PhD, Kengo Kinoshita, PhD, Masayuki Yamamoto, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 2, Iss 1, Pp 100113- (2022)
Purpose: To elucidate the differences in ocular biometric parameters by generation and gender and to identify axial length (AL)-associated genetic variants in Japanese individuals, we analyzed Tohoku Medical Megabank Organization (ToMMo) Eye Study da
Externí odkaz:
https://doaj.org/article/24b1a249dcc44067a7c370d61f462368
Autor:
Mika Sakurai-Yageta, Hiroshi Kawame, Shinichi Kuriyama, Atsushi Hozawa, Naoki Nakaya, Fuji Nagami, Naoko Minegishi, Soichi Ogishima, Takako Takai-Igarashi, Inaho Danjoh, Taku Obara, Mami Ishikuro, Tomoko Kobayashi, Yayoi Aizawa, Rino Ishihara, Masayuki Yamamoto, Yoichi Suzuki
Publikováno v:
BMC Medical Education, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Genome cohort studies are used to analyze interactions between genetic and environmental factors, providing valuable information for personalized healthcare. Large-scale and long-term cohort studies require a number of specially t
Externí odkaz:
https://doaj.org/article/55090c6c2b734afb88aff6f611fe847a
Oral Microbiome Analysis in Prospective Genome Cohort Studies of the Tohoku Medical Megabank Project
Autor:
Sakae Saito, Yuichi Aoki, Toru Tamahara, Maki Goto, Hiroyuki Matsui, Junko Kawashima, Inaho Danjoh, Atsushi Hozawa, Shinichi Kuriyama, Yoichi Suzuki, Nobuo Fuse, Shigeo Kure, Riu Yamashita, Osamu Tanabe, Naoko Minegishi, Kengo Kinoshita, Akito Tsuboi, Ritsuko Shimizu, Masayuki Yamamoto
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
A baseline oral microbiome study of the Tohoku Medical Megabank Organization (TMM) was planned to characterize the profile of the oral microbiome in the Japanese population. The study also aimed to clarify risk factors for multifactorial diseases by
Externí odkaz:
https://doaj.org/article/9a24a0a4c6154f059523791ac9c6e3b9
Autor:
Takako Takai-Igarashi, Kengo Kinoshita, Masao Nagasaki, Soichi Ogishima, Naoki Nakamura, Sachiko Nagase, Satoshi Nagaie, Tomo Saito, Fuji Nagami, Naoko Minegishi, Yoichi Suzuki, Kichiya Suzuki, Hiroaki Hashizume, Shinichi Kuriyama, Atsushi Hozawa, Nobuo Yaegashi, Shigeo Kure, Gen Tamiya, Yoshio Kawaguchi, Hiroshi Tanaka, Masayuki Yamamoto
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background With the goal of realizing genome-based personalized healthcare, we have developed a biobank that integrates personal health, genome, and omics data along with biospecimens donated by volunteers of 150,000. Such a large-scale of d
Externí odkaz:
https://doaj.org/article/48a22d423bcf48b2b7054374e5157f07
Autor:
Naoko Ozawa, Naoki Shimojo, Yoichi Suzuki, Shingo Ochiai, Taiji Nakano, Yoshinori Morita, Yuzaburo Inoue, Takayasu Arima, Shuichi Suzuki, Yoichi Kohno
Publikováno v:
Allergology International, Vol 63, Iss 2, Pp 261-266 (2014)
Background: There are reports that the maternal diet during pregnancy may affect development of babies' eczema. We sought to investigate the association between the maternal diet during pregnancy and the risk of eczema in infancy in Japan. Methods: A
Externí odkaz:
https://doaj.org/article/40824fa142a740688203d89c4bf2f15e
Autor:
Eiichiro Nagata, Natsuko Fujii, Kazuyoshi Hosomichi, Shigeki Mitsunaga, Yoichi Suzuki, Yoichi Mashimo, Hideo Tsukamoto, Tadayuki Satoh, Motoki Osawa, Ituro Inoue, Akira Hata, Shunya Takizawa
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105319 (2014)
To identify the genetic causality of migraine and acute, severe melalgia, we performed a linkage analysis and exome sequencing in a family with four affected individuals. We identified a variant (R21L) in exon 2 of the GC globulin gene, which is invo
Externí odkaz:
https://doaj.org/article/f9f6bf6d7591473797c40863b7935963