Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yoichi Kawanishi"'
Publikováno v:
Clinical Neuropsychopharmacology and Therapeutics. 10:26-28
Autor:
Yoichi Kawanishi, Koubun Imai, Takashi Asada, Hirokazu Tachikawa, Takehito Okubo, Shoji Harada
Publikováno v:
American Journal of Medical Genetics. 114:605-608
The human γ-aminobutyric acid type B (GABAB) receptor gene is a candidate gene for schizophrenia due to its chromosomal location and neurobiologic roles. In the present study, association analyses of genetic polymorphisms of the GABAB receptor gene
Publikováno v:
Psychiatry Research. 103:147-155
Cholecystokinin A receptors (CCKAR) modulate CCK-stimulated dopamine release, and mutations in the CCKAR gene may predispose affected individuals to schizophrenia. Our previous study suggested that -286A>G polymorphism (previously named 201A>G) in th
Publikováno v:
Biochemical and Biophysical Research Communications. 281:267-271
Recent studies have revealed that GSTM1 and M2 of the μ-class glutathione S-transferases catalyze a glutathione conjugate of catechol o-quinones including dopachrome, noradrenochrome, and adrenochrome under physiological conditions. Reduced or negat
Autor:
Toshihito Suzuki, Takehito Okubo, Hirokazu Tachikawa, Yoichi Kawanishi, Koubun Imai, Shoji Harada
Publikováno v:
Neuropsychobiology. 43:237-241
The human synapsin III gene, located on chromosome 22q12–13, has previously been reported to indicate a susceptibility for schizophrenia. Noval rare variants (Thr136Thr in exon 3, Pro468Ser, Glu525Gln and Pro534Leu in exon 12, and 1769 G/C in the u
Publikováno v:
European Journal of Pharmacology. 410:227-241
Although antipsychotic drugs are effective in alleviating schizophrenic symptoms, individual differences in patient response suggest that genetic components play a major role, and pharmacogenetic studies have indicated the possibility for a more indi
Publikováno v:
Journal of Human Genetics. 45:24-30
The transcription factor activator protein 2 (AP-2) gene is a possible candidate gene for schizophrenia, since it maps near D6S470, a marker on chromosome 6p24 that provided evidence of linkage to schizophrenia. In the present study we analyzed the p
Publikováno v:
American Journal of Medical Genetics. 81:434-439
Dysfunction of serotonin systems has been implicated in schizophrenia. In the present study, the human 5-HT1A receptor gene containing the 5' untranslated region was screened in order to detect genetic variations, through which alteration of protein
Autor:
Hiroyasu Shiraishi, Masashi Hori, Takafumi Hori, Hirokazu Tachikawa, Yoichi Kawanishi, Toshihito Suzuki
Publikováno v:
Psychiatry and Clinical Neurosciences. 54:503-505
Two cases of tardive dystonia are reported. The first case was an 18-year-old schizophrenic woman suffering from parkinsonism and hypotension induced by antipsychotic drugs. Risperidone (4 mg/day) was added to her drug regimen and after increasing th
Publikováno v:
Journal of Human Genetics. 44:428-430
Cyclic AMP-responsive element-binding protein (CREB) is one of the messenger molecules involved in intracellular signal transduction pathways used by most dopamine and serotonin receptor subtypes. In addition, CREB stimulates the expression of a numb