Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yoichi, Kurebayashi"'
Autor:
Michiru Otaki, Nozomi Hirane, Yayoi Natsume-Kitatani, Mari Nogami Itoh, Masanori Shindo, Yoichi Kurebayashi, Shin-Ichiro Nishimura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract This study presents “mouse tissue glycome atlas” representing the profiles of major N-glycans of mouse glycoproteins that may define their essential functions in the surface glycocalyx of mouse organs/tissues and serum-derived extracellu
Externí odkaz:
https://doaj.org/article/5de9196a41814d5181581bf61c051185
Autor:
Yoichi Kurebayashi
Publikováno v:
Translational and Regulatory Sciences. 1:1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52f449e10815a04910c634645e63dbf6
https://doi.org/10.33611/trs.1_1
https://doi.org/10.33611/trs.1_1
Publikováno v:
The Kobe journal of medical sciences. 62(6)
Tofacitinib (3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3 -oxopropanenitrile) is an oral Janus kinase inhibitor that is approved in countries including Japan and the United States for the treatment of rheumato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36775d9e06c517c5f54a3904ce84f00d
https://pubmed.ncbi.nlm.nih.gov/28490712
https://pubmed.ncbi.nlm.nih.gov/28490712
Publikováno v:
The Kobe journal of medical sciences. 62(4)
Psoriasis is a chronic inflammatory skin disease mediated by dysregulated auto-reactive immune system. In this study, in order to confirm and further extend the pharmacological basis of topical steroids in psoriasis therapy, we investigated the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8fd610507ff2978936bf411f4b1ce86
https://pubmed.ncbi.nlm.nih.gov/28239073
https://pubmed.ncbi.nlm.nih.gov/28239073
Publikováno v:
The Kobe journal of medical sciences. 62(2)
VLA-1 (very late antigen-1) is implicated in recruitment, retention and activation of leukocytes and its blockade has been referred as a potential target of new drug discovery to address unmet medical needs in inflammatory disease area. In the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5f8fbc7005391f102dc6bab241007aa
https://pubmed.ncbi.nlm.nih.gov/27578034
https://pubmed.ncbi.nlm.nih.gov/27578034
Publikováno v:
European Journal of Pharmacology. 643:107-112
Pregabalin, a ligand of alpha(2)delta subunits of voltage-gated calcium channels, reduces visceral hypersensitivity associated with irritable bowel syndrome. However, effects of pregabalin on bowel function are not well described. We investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85bae8c2a13346db73ac9f463ad523b
https://doi.org/10.1016/j.ejphar.2010.06.014
https://doi.org/10.1016/j.ejphar.2010.06.014
Autor:
D Himaki, John B. Furness, Mitsuhisa Kawai, Yoichi Kurebayashi, K Nagao, Jeremy D. Gale, Katsuyo Ohashi-Doi
Publikováno v:
Neurogastroenterology & Motility. 22:e69-e76
RS-127445 is a selective, high affinity 5-HT(2B)receptor antagonist. We investigated whether 5-HT(2B)receptor antagonists can reduce colonic visceral hypersensitivity caused by restraint stress or by proximal colonic inflammation.Visceral hypersensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ceebbab99c6d2047ca1db697e43e0b
https://doi.org/10.1111/j.1365-2982.2009.01395.x
https://doi.org/10.1111/j.1365-2982.2009.01395.x
An experimental model of visceral pain: its application to explore molecular targets for IBS therapy
Autor:
Katsuyo Ohashi-Doi, Yoichi Kurebayashi
Publikováno v:
Folia Pharmacologica Japonica. 133:194-198
過敏性腸症候群（Irritable Bowel Syndrome：IBS）は，機能性消化管障害に分類され，便通異常（便秘や下痢）と慢性的な腹痛（内臓知覚過敏）を伴う疾患である．IBSの発症原因を特定すること
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993ca7505d78806bfd1a66c3a3368d8f
https://doi.org/10.1254/fpj.133.194
https://doi.org/10.1254/fpj.133.194
Autor:
Yasuhito Taniguchi, Takeshi Aihara, Teruhisa Kato, Akiko Hirao, Minoru Sakakibara, Hiroki Mori, Nobuyuki Takahashi, Hiroyuki Ohshiro, Yasuo Ochi, Hiroko Tonai-Kachi, Yoichi Kurebayashi
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 328:671-679
Inhibition of H(+),K(+)-ATPase is accepted as the most effective way of controlling gastric acid secretion. However, current acid suppressant therapy for gastroesophageal reflux disease, using histamine H(2) receptor antagonists and proton pump inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cb9687c1214bd3436c99f2d53af69ad
https://doi.org/10.1124/jpet.108.146415
https://doi.org/10.1124/jpet.108.146415
Autor:
Katsuomi Ichikawa, Laigao Chen, Katsuyo Ohashi, Yoichi Kurebayashi, Michael J. Callahan, Kenneth R. Zasadny
Publikováno v:
Journal of Veterinary Medical Science. 70:43-49
Using microPET and (18)F-fluorodeoxyglucose ((18)F-FDG) as a tracer, we investigated regional brain activation in a rat model of visceral hypersensitivity induced by 2,4,6-trinitrobenzene sulfonic acid (TNBS). TNBS injection into the proximal colon t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012d1a5665e3ec271ba3bec9acf318b9
https://doi.org/10.1292/jvms.70.43
https://doi.org/10.1292/jvms.70.43