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of 34
pro vyhledávání: '"Yohta, Fukuda"'
Autor:
Rakesh Maharjan, Yohta Fukuda, Taisuke Nakayama, Toru Nakayama, Hiroki Hamada, Shin-ichi Ozaki, Tsuyoshi Inoue
Publikováno v:
Acta Crystallographica Section D Structural Biology. 78:379-389
Capsaicinoids are phenolic compounds that have health benefits. However, the pungency and poor water solubility of these compounds limit their exploitation. Glycosylation is a powerful method to improve water solubility and reduce pungency while pres
Publikováno v:
Protein Science. 29:1829-1835
Cytochrome b5 is an essential electron transfer protein, which is ubiquitously found in living systems and involved in wide variety of biological processes. Tardigrades (also known as water bears), some of which are famous for desiccation resistance,
Autor:
Koki Kawakami, Shin-ichi Ozaki, Yuta Okimoto, Rakesh Maharjan, Naomichi Shimomura, Toru Nakayama, Tsuyoshi Inoue, Taisuke Nakayama, Yohta Fukuda, Hiroki Hamada
Publikováno v:
Biochemistry. 59:2551-2561
The glycosylation of small hydrophobic compounds is catalyzed by uridine diphosphate glycosyltransferases (UGTs). Because glycosylation is an invaluable tool for improving the stability and water solubility of hydrophobic compounds, UGTs have attract
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance X-ray crystallography often fails to determine the positions of hydrogen atoms, which play crucial roles in enzymatic reactions. Despite many X-ray crystallographic studies, the reaction mechanism of copper-containing nitrite reductases
Autor:
Tingting Yang, Nancy Ward, Alec Kittredge, Shoudeng Chen, Yu Zhang, Changyi Ji, Yohta Fukuda, Austin Hopiavuori
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-13 (2019)
Communications Biology
Communications Biology
Mutations of human BEST1, encoding a Ca2+-activated Cl− channel (hBest1), cause macular degenerative disorders. Best1 homolog structures reveal an evolutionarily conserved channel architecture highlighted by two landmark restrictions (named the “
Publikováno v:
The FEBS Journal. 286:1287-1304
Tardigrades, also known as water bears, can survive extreme conditions. For example, tardigrades have high tolerance to extreme desiccation because they can enter an anhydrobiotic state, in which they show no or nearly undetectable metabolic processe
Autor:
Yohta Fukuda, Tsuyoshi Inoue
Publikováno v:
Protein Science : A Publication of the Protein Society
Some tardigrades can survive extremely desiccated conditions through transition into a state called anhydrobiosis. Anhydrobiotic tardigrades have proteins unique to them and they are thought to be keys to the understanding of unusual desiccation resi
Publikováno v:
Journal of biochemistry. 169(6)
Tardigrades, a phylum of meiofaunal organisms, exhibit extraordinary tolerance to various environmental conditions, including extreme temperatures (−273 to 151°C) and exposure to ionizing radiation. Proteins from anhydrobiotic tardigrades with hom
Publikováno v:
Protein Science : A Publication of the Protein Society
Cytochrome b 5 is an essential electron transfer protein, which is ubiquitously found in living systems and involved in wide variety of biological processes. Tardigrades (also known as water bears), some of which are famous for desiccation resistance
Autor:
Rakesh Maharjan, Taisuke Nakayama, Toru Nakayama, Tsuyoshi Inoue, Yohta Fukuda, Hiroki Hamada, Shin-ichi Ozaki
Publikováno v:
Acta crystallographica. Section D, Structural biology. 76(Pt 6)
Uridine diphosphate glycosyltransferases (UGTs) are ubiquitous enzymes that are involved in the glycosylation of small molecules. As glycosylation improves the water solubility and stability of hydrophobic compounds, interest in the use of UGTs for t