Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yohsuke Shimada"'
Autor:
Takahiro Kasai, Takashi Wada, Tsubasa Iijima, Yoshiko Minami, Tomoyo Sakaguchi, Ryotaro Koga, Tomoki Shiratori, Yuta Otsuka, Yohsuke Shimada, Yukiko Okayama, Satoru Goto
Publikováno v:
BBA Advances, Vol 2, Iss , Pp 100036- (2022)
Amyloid fibrillation is provoked by the conformational rearrangement of its source. In our previous study, we claimed that the conformational rearrangement of hen egg white lysozyme requires intermolecular aggregation/packing induced. Our proposed ca
Externí odkaz:
https://doaj.org/article/9621626ab6ac4705b0095199980e6f01
Publikováno v:
BBA Advances, Vol 1, Iss , Pp 100030- (2021)
Many natural compounds mop up radicals and limit radical reactions and may prove useful in reducing or preventing oxidative stress-related diseases in vivo. Several assays have been developed to measure antioxidant or anti-radical activity. Here, we
Externí odkaz:
https://doaj.org/article/f9da5f0f82004817b1b81e831f02a54e
Autor:
Takatoshi, Kinoshita, Chihiro, Tsunoda, Satoru, Goto, Kanji, Hasegawa, Hitoshi, Chatani, Momoko, Fujita, Hikaru, Kataoka, Yuta, Katahara, Yohsuke, Shimada, Yuta, Otsuka, Kazushi, Komatsu, Hiroshi, Terada
Publikováno v:
Chemical and Pharmaceutical Bulletin. 70:120-129
Certain combinations of acidic and basic drugs can cause significant changes in physicochemical properties through the formation of ionic liquids, eutectic mixtures, or deep eutectic solvents. In particular, combining indomethacin and lidocaine is kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2afbd7000f08341e405d00fb0479983
https://doi.org/10.1248/cpb.c21-00834
https://doi.org/10.1248/cpb.c21-00834
Autor:
Risa Ichii, Shota Shimizu, Yingpeng Li, Ryosuke Hiroshige, Kosho Makino, Hideyo Takahashi, Yohsuke Shimada, Ayako Wada-Hirai, Yuta Otsuka, Satoru Goto
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 102:327-338
Antioxidants scavenge free radicals and may help prevent disease. However, due to poor stability, continuous intake is required. This study investigates the ability of cyclodextrin inclusion to improve the stability of the novel antioxidant edaravone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4431e862295f26e8c777169cac60ed16
https://doi.org/10.1007/s10847-021-01122-1
https://doi.org/10.1007/s10847-021-01122-1
Publikováno v:
Journal of Pharmaceutical Sciences. 110:1142-1147
This study investigated the effect of phase transformation on indomethacin (IMC), cimetidine (CIM), and their 1:1 eutectic mixture, using FTIR spectra and multivariate analysis. The IMC form γ, CIM form A, and IMC-CIM 1:1 mixture molar ratio samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e81ad5e2c39ffa2187e24532fce4aad
https://doi.org/10.1016/j.xphs.2020.09.049
https://doi.org/10.1016/j.xphs.2020.09.049
Publikováno v:
Journal of Pharmaceutical Sciences. 109:2206-2212
Cyclodextrins (CDs) form complex crystals with drugs and improve physicochemical properties of drugs. However, only few reports have summarized relationships between crystal structures of drug/CD and dissolution behavior. In this study, we developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24656ab062479fa88e4f3f20fe86cf7f
https://doi.org/10.1016/j.xphs.2020.03.029
https://doi.org/10.1016/j.xphs.2020.03.029
Autor:
Yuta Otsuka, Hiroshi Terada, Katsuyuki Inoo, Momoko Fujita, Hitoshi Chatani, Satoru Goto, Yohsuke Shimada
Publikováno v:
RSC Advances. 10:1572-1579
Polymers have been recognized to have the function of sustaining the supersaturated state of drugs. This function has been widely studied because it will improve the absorption of poorly water-soluble drugs. However, clarifying the mechanism of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d23db9e80b133a18a294eb9e55cd87ec
https://doi.org/10.1039/c9ra09952b
https://doi.org/10.1039/c9ra09952b
Autor:
Takahiro Kasai, Takashi Wada, Tsubasa Iijima, Yoshiko Minami, Tomoyo Sakaguchi, Ryotaro Koga, Tomoki Shiratori, Yuta Otsuka, Yohsuke Shimada, Yukiko Okayama, Satoru Goto
Publikováno v:
BBA Adv
BBA Advances, Vol 2, Iss, Pp 100036-(2022)
BBA Advances, Vol 2, Iss, Pp 100036-(2022)
Amyloid fibrillation is provoked by the conformational rearrangement of its source. In our previous study, we claimed that the conformational rearrangement of hen egg white lysozyme requires intermolecular aggregation/packing induced. Our proposed ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50645a59099387c81bcc80e71105ca57
https://europepmc.org/articles/PMC10074904/
https://europepmc.org/articles/PMC10074904/
Publikováno v:
BBA Adv
BBA Advances, Vol 1, Iss, Pp 100030-(2021)
BBA Advances, Vol 1, Iss, Pp 100030-(2021)
Many natural compounds mop up radicals and limit radical reactions and may prove useful in reducing or preventing oxidative stress-related diseases in vivo. Several assays have been developed to measure antioxidant or anti-radical activity. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19f3fc28ad6ff31cdaed1da8da503dd
https://europepmc.org/articles/PMC10074949/
https://europepmc.org/articles/PMC10074949/
Autor:
Yohsuke Shimada, Satoru Goto, Risa Ichii, Yuta Otsuka, Momoko Fujita, Ryosuke Hiroshige, Shota Shimizu, Chihiro Tsunoda, Ayako Wada-Hirai, Ying Peng Li
Publikováno v:
Journal of pharmaceutical sciences. 110(11)
The purpose of this study is to find that a small amount of 2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) can produce a parachute effect on indomethacin (INM). From the examination of dissolution curves and concentration after several days, the supersat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d8c966ca74ba3a03fac7fb64fbed76
https://pubmed.ncbi.nlm.nih.gov/34364701
https://pubmed.ncbi.nlm.nih.gov/34364701