Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yohko Nakagawa"'
Autor:
Megumi Takahashi, Hidemi Takahashi, Yasuyuki Negishi, Masumi Shimizu, Masao Ichikawa, Yohko Nakagawa
Publikováno v:
Immunology Letters. 167:72-86
The major effector cells for cellular adaptive immunity are CD8+ cytotoxic T lymphocytes (CTLs), which can recognize and kill virus-infected cells and tumor cells. Although CTLs exhibit strong cytolytic activity against target cells in vitro, a numbe
Autor:
Harini G. Acharya, Maria Tzardi, Yasuyuki Negishi, Constantina A. Pappa, Quoc Thai Dinh, Hans Jürgen Hoffmann, Carlos Senent, George Tsirakis, Gabriela Canto, Ralph Mösges, Michael G. Alexandrakis, Maria Devetzoglou, María José Torres, Rosario Gonzalez-Mendiola, Robert Bals, Nieves Cabañes, Ayako Wakabayashi, Masumi Shimizu, Anatoli Astvatsatourov, Rodanthi Vyzoukaki, Juliane Nguyen, Adriana Ariza, Per Stahl-Skov, Ricardo Palacios, Cristobalina Mayorga, Claas Gloistein, Yohko Nakagawa, Kimihiro Okubo, Silke Allekotte, Francisca Arribas, Babu Gonipeta, Venu Gangur, Druckerei Stückle, Sebastian Heck, Satz Mengensatzproduktion, Galicia Davila, Fernando Pineda, Natalia Blanca-López, Duc Dung Le, Takachika Hiroi, Jose Julio Laguna, Hidemi Takahashi, Sitaram Parvataneni, Miguel Blanca, Ryosuke Murakami
Publikováno v:
International Archives of Allergy and Immunology. 168:I-IV
Autor:
Katsuhisa Nakatsuka, Hidemi Takahashi, Yohko Nakagawa, Ayako Wakabayashi, Hirotomo Harimoto, Masumi Shimizu, Choitsu Sakamoto
Publikováno v:
Immunology and Cell Biology
Cancer immunosurveillance failure is largely attributed to the insufficient activation of tumor-specific class I major histocompatibility complex (MHC) molecule (MHC-I)-restricted CD8⁺ cytotoxic T lymphocytes (CTLs). DEC-205⁺ dendritic cells (DCs
Publikováno v:
International Immunology. 25:11-24
We have previously reported that the cytotoxic activity of murine CD8(+) CTLs specific for HIV-1 gp160 envelope protein was markedly inhibited in vitro by brief exposure to a free epitope peptide P18-I10 (aa: RGPGRAFVTI) using the epitope-specific CT
Autor:
Hidemi Takahashi, Fumiko Kobayashi, Yoshitaka Fukunaga, Eri Watanabe, Yoshihiko Norose, Shingo Yamanishi, Yohko Nakagawa
Publikováno v:
Infection and Immunity. 79:4791-4801
Helicobacter pylori infection is associated with several autoimmune diseases, in which autoantibody-producing B cells must be activated. Among these B cells, CD5-positive B-1a cells from BALB/c mice were confirmed to secrete autoantibodies when cocul
Publikováno v:
Biomedical Research. 32:159-166
Assays for cytotoxicity of CTLs in vivo using a fluorescent-based dye, 5- (and 6-) carboxyfluorescein diacetate succinimydyl ester (CFSE), have been established and widely used. On the basis of this experience, we applied it to in vitro assay system
Publikováno v:
Biophysical Journal. 92:2570-2582
For the structural analysis of T-cell receptor (TCR) and peptide/MHC interaction, a series of peptides with a single amino acid substitution by a corresponding d-amino acid, having the same weight, size, and charge, within P18-I10 (aa318–327: RGPGR
Autor:
Yasuyuki Negishi, Hidemi Takahashi, Kimihiro Okubo, Yohko Nakagawa, Ayako Wakabayashi, Masumi Shimizu, Takachika Hiroi, Ryosuke Murakami
Publikováno v:
International archives of allergy and immunology. 168(4)
Background: Two major distinct subsets of dendritic cells (DCs) are arranged to regulate immune responses: DEC-205+ DCs drive Th1 polarization and 33D1+ DCs establish Th2 dominancy. Th1 polarization can be achieved either by depletion of 33D1+ DCs wi
Autor:
Yohko Nakagawa, Kazuo Shimizu, Ritsuko Ishii, Hidemi Takahashi, Shigeo Tanaka, Masumi Shimizu
Publikováno v:
Cancer Immunology, Immunotherapy. 53:383-390
Many murine tumor cells express not only individual haplotype-matched class I MHC molecules, but also species-specific CD1d molecules. The former class I MHC molecules generally present internally synthesized tumor-derived peptide antigens to highly
Autor:
Ayako Wakabayashi, Yohko Nakagawa, David H. Margulies, Hiroshi Kaneko, Yoshihiko Norose, Yoshihiro Kumagai, Jian Wang, Masumi Shimizu, Hidemi Takahashi, Hideki Kuribayashi
Publikováno v:
Biochemical and Biophysical Research Communications. 316:356-363
For the analysis of mucosal immunity to HIV-1, we have recently established a line of transgenic (Tg) mice expressing the TCRalpha and TCRbeta genes of the murine CTL clone RT1 specific for P18-I10 (RGPGRAFVTI), an immunodominant gp160 envelope-deriv