Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yohei Tsukada"'
Autor:
Yohei Tsukada, Fumitaka Muramatsu, Yumiko Hayashi, Chiaki Inagaki, Hang Su, Tomohiro Iba, Hiroyasu Kidoya, Nobuyuki Takakura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Angiogenesis contributes to numerous pathological conditions. Understanding the molecular mechanisms of angiogenesis will offer new therapeutic opportunities. Several experimental in vivo models that better represent the pathological conditi
Externí odkaz:
https://doaj.org/article/3dc28d15ce0443be96af6006545bcfeb
Autor:
Kazuhiro Takara, Daisuke Eino, Koji Ando, Daisuke Yasuda, Hisamichi Naito, Yohei Tsukada, Tomohiro Iba, Taku Wakabayashi, Fumitaka Muramatsu, Hiroyasu Kidoya, Shigetomo Fukuhara, Naoki Mochizuki, Satoshi Ishii, Haruhiko Kishima, Nobuyuki Takakura
Publikováno v:
Cell Reports, Vol 20, Iss 9, Pp 2072-2086 (2017)
Vascular normalization in tumors may improve drug delivery and anti-tumor immunity. Angiogenesis inhibitors induce hypoxia, which may facilitate malignant progression; therefore, we investigated other methods to promote vascular maturation. Here, we
Externí odkaz:
https://doaj.org/article/812d1475ee78429d99eb5acd0194da19
Autor:
Kazutake Tsujikawa, Norio Nonomura, Motohide Uemura, Kazutoshi Fujita, Wataru Nakata, Takumi Kobayashi, Yohei Tsukada, Yuri Kashiwagi, Ryoji Kawakami, Ikumi Ohshio, Hiroshi Egawa, Hiroaki Hase, Kaori Kitae, Yuko Ueda, Kentaro Jingushi
Supplementary Figure S4. A, ACHN cells were transfected with TRIM33 siRNA or control siRNA for 24 h and then stimulated with or without TGF-β1 for 48 h. A wound was then formed by scraping and was measured after 24 h. The results are means {plus min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a60d22679830b125503a6ee70ad70a
https://doi.org/10.1158/1541-7786.22517760.v1
https://doi.org/10.1158/1541-7786.22517760.v1
Autor:
Kazutake Tsujikawa, Norio Nonomura, Motohide Uemura, Kazutoshi Fujita, Wataru Nakata, Takumi Kobayashi, Yohei Tsukada, Yuri Kashiwagi, Ryoji Kawakami, Ikumi Ohshio, Hiroshi Egawa, Hiroaki Hase, Kaori Kitae, Yuko Ueda, Kentaro Jingushi
Renal cell carcinoma (RCC) is the most common neoplasm of the adult kidney, and clear cell RCC (ccRCC) represents its most common histological subtype. To identify a therapeutic target for ccRCC, miRNA expression signatures from ccRCC clinical specim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7fef5b6d2abc511c278402ceb736f0
https://doi.org/10.1158/1541-7786.c.6541818
https://doi.org/10.1158/1541-7786.c.6541818
Autor:
Nobuyuki Takakura, Haruhiko Kishima, Kazuhiro Takara, Yasunori Fujimoto, Naoki Kagawa, Hideyuki Arita, Hiroyasu Kidoya, Fumitaka Muramatsu, Taku Wakabayashi, Tomohiro Iba, Yonehiro Kanemura, Hisamichi Naito, Yohei Tsukada, Daisuke Eino
The structure and function of tumor blood vessels profoundly affects the tumor microenvironment. Signals mediated through the lysophosphatidic acid receptor 4 (LPA4) promote vascular network formation to restore normal vascular barrier function in su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f19d7f4fcae5bbd84bdd2e265d379da
https://doi.org/10.1158/0008-5472.c.6510116.v1
https://doi.org/10.1158/0008-5472.c.6510116.v1
Autor:
Nobuyuki Takakura, Haruhiko Kishima, Kazuhiro Takara, Yasunori Fujimoto, Naoki Kagawa, Hideyuki Arita, Hiroyasu Kidoya, Fumitaka Muramatsu, Taku Wakabayashi, Tomohiro Iba, Yonehiro Kanemura, Hisamichi Naito, Yohei Tsukada, Daisuke Eino
Supplementary Figure 1. Coverage of pericyte and the basal membrane by LPA. Expression of LPA4 in several tumors. Supplementary Figure 2. Survival of wild-type and LPA4-KO mice harboring LLC brain tumors treated with or without LPA in the presence or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3c3a725991b523b5aa3ae620bbe4d2
https://doi.org/10.1158/0008-5472.22418390.v1
https://doi.org/10.1158/0008-5472.22418390.v1
Autor:
Chiaki Inagaki, Yohei Tsukada, Hang Su, Yumiko Hayashi, Tomohiro Iba, Nobuyuki Takakura, Hiroyasu Kidoya, Fumitaka Muramatsu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Angiogenesis contributes to numerous pathological conditions. Understanding the molecular mechanisms of angiogenesis will offer new therapeutic opportunities. Several experimental in vivo models that better represent the pathological conditions have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bdd454d3339dde10eed084b10f1c30
https://doaj.org/article/3dc28d15ce0443be96af6006545bcfeb
https://doaj.org/article/3dc28d15ce0443be96af6006545bcfeb
Autor:
Yonehiro Kanemura, Yasunori Fujimoto, Fumitaka Muramatsu, Daisuke Eino, Naoki Kagawa, Hisamichi Naito, Taku Wakabayashi, Hiroyasu Kidoya, Kazuhiro Takara, Nobuyuki Takakura, Tomohiro Iba, Hideyuki Arita, Yohei Tsukada, Haruhiko Kishima
Publikováno v:
Cancer Research. 78:6607-6620
The structure and function of tumor blood vessels profoundly affects the tumor microenvironment. Signals mediated through the lysophosphatidic acid receptor 4 (LPA4) promote vascular network formation to restore normal vascular barrier function in su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7b40cc95829c3433ba55185a060a59
https://doi.org/10.1158/0008-5472.can-18-0498
https://doi.org/10.1158/0008-5472.can-18-0498
Autor:
Shigetomo Fukuhara, Hisamichi Naito, Daisuke Eino, Koji Ando, Satoshi Ishii, Daisuke Yasuda, Hiroyasu Kidoya, Naoki Mochizuki, Nobuyuki Takakura, Tomohiro Iba, Taku Wakabayashi, Fumitaka Muramatsu, Kazuhiro Takara, Yohei Tsukada, Haruhiko Kishima
Publikováno v:
Cell Reports, Vol 20, Iss 9, Pp 2072-2086 (2017)
Summary Vascular normalization in tumors may improve drug delivery and anti-tumor immunity. Angiogenesis inhibitors induce hypoxia, which may facilitate malignant progression; therefore, we investigated other methods to promote vascular maturation. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7950fd76949fc5e07f5825bb3678fd8e
https://doi.org/10.1016/j.celrep.2017.07.080
https://doi.org/10.1016/j.celrep.2017.07.080
Autor:
Kentaro Jingushi, Tomoki Shimanoe, Hiroaki Hase, Yohei Tsukada, Kazuhiro Nakajima, Ryoji Kawakami, Yasuka Saigo, Kaori Kitae, Ikumi Ohshio, Yuko Ueda, Kazutake Tsujikawa
Publikováno v:
Biochemical and Biophysical Research Communications. 477:413-418
Human AlkB homolog 8 (ALKBH8) is highly expressed in high-grade, superficially and deeply invasive bladder cancer. Moreover, ALKBH8 knockdown induces apoptosis in bladder cancer cells. However, the underlying anti-apoptotic mechanism of ALKBH8 in bla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df8a843ff19f1ab22a6b27fa93162c8
https://doi.org/10.1016/j.bbrc.2016.06.084
https://doi.org/10.1016/j.bbrc.2016.06.084