Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Yohei Tomita"'
Autor:
Momoka Midorikawa, Kiwako Mori, Hidemasa Torii, Yohei Tomita, Yan Zhang, Kazuo Tsubota, Toshihide Kurihara, Kazuno Negishi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract High myopia can lead to pathologic myopia and visual impairment, whereas its causes are unclear. We retrospectively researched high myopia cases from patient records to investigate the association between axial elongation and myopic maculopa
Externí odkaz:
https://doaj.org/article/b05c28d65163471a884e25c0cc57a822
Autor:
Jean-Charles Fruchart, Jamila Fruchart-Najib, Shizuya Yamashita, Peter Libby, Koutaro Yokote, Tatsuhiko Kodama, Yohei Tomita, Paul M. Ridker, Michel P. Hermans, Alberto Zambon
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-8 (2024)
Abstract The neutral result of the PROMINENT trial has led to questions about the future for pemafibrate. This commentary discusses possible reasons for the lack of benefit observed in the trial. There were, however, indicators suggesting therapeutic
Externí odkaz:
https://doaj.org/article/59123db750ae4b5c876f8af1f2d916c1
Autor:
Deokho Lee, Yohei Tomita, Yukihiro Miwa, Hiromitsu Kunimi, Ayaka Nakai, Chiho Shoda, Kazuno Negishi, Toshihide Kurihara
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10140 (2024)
Hypoxia-inducible factors (HIFs) are transcriptional factors that function as strong regulators of oxygen homeostasis and cellular metabolisms. The maintenance of cellular oxygen levels is critical as either insufficient or excessive oxygen affects d
Externí odkaz:
https://doaj.org/article/c19d15c6073e4fec86023f7aff57fdb6
Autor:
Mariko Sasaki, Kenya Yuki, Akiko Hanyuda, Kazumasa Yamagishi, Kaoru Motomura, Toshihide Kurihara, Yohei Tomita, Kiwako Mori, Nobuhiro Ozawa, Yoko Ozawa, Norie Sawada, Kazuno Negishi, Kazuo Tsubota, Shoichiro Tsugane, Hiroyasu Iso
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Residents of Chikusei City, aged 40–74 years, underwent systemic and ophthalmological screening, and participants with diabetes were included in this analysis. Dietary intake was assessed using a food frequency questionnaire and calculated
Externí odkaz:
https://doaj.org/article/3d6640c2f4c846a38de32fdb28cd53bd
Publikováno v:
PeerJ, Vol 11, p e14611 (2023)
Background Pathological choroidal neovascularization (CNV) is one of the major causes of visual impairment in neovascular age-related macular degeneration (AMD). CNV has been suppressed by using anti-vascular endothelial growth factor (VEGF) antibodi
Externí odkaz:
https://doaj.org/article/4e9dd89e454a4983840111b556bc9e35
Autor:
Zhongxiao Wang, Felix Yemanyi, Alexandra K Blomfield, Kiran Bora, Shuo Huang, Chi-Hsiu Liu, William R Britton, Steve S Cho, Yohei Tomita, Zhongjie Fu, Jian-xing Ma, Wen-hong Li, Jing Chen
Publikováno v:
eLife, Vol 11 (2022)
Amino acid (AA) metabolism in vascular endothelium is important for sprouting angiogenesis. SLC38A5 (solute carrier family 38 member 5), an AA transporter, shuttles neutral AAs across cell membrane, including glutamine, which may serve as metabolic f
Externí odkaz:
https://doaj.org/article/1dca4eca0ee9404c909a3ba3fa5dce44
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 7, Pp 1495-1496 (2023)
Externí odkaz:
https://doaj.org/article/12f0652036884801a25eaff9e156b5bd
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5371 (2023)
Disorders in the development and regulation of blood vessels are involved in various ocular disorders, such as persistent hyperplastic primary vitreous, familial exudative vitreoretinopathy, and choroidal dystrophy. Thus, the appropriate regulation o
Externí odkaz:
https://doaj.org/article/dcb311f532ee43f1b01278162e910062
Autor:
Tianxi Wang, Pingzhu Zhou, Xuemei Xie, Yohei Tomita, Steve Cho, Demetrios Tsirukis, Enton Lam, Hongbo Robert Luo, Ye Sun
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103632- (2021)
Background: Pathological neovascularization in neovascular age-related macular degeneration (nAMD) is the leading cause of vision loss in the elderly. Increasing evidence shows that cells of myeloid lineage play important roles in controlling patholo
Externí odkaz:
https://doaj.org/article/a4e11b7757914aaa9fdcb54fb0eb7066
Autor:
Deokho Lee, Yohei Tomita, Yukihiro Miwa, Heonuk Jeong, Ari Shinojima, Norimitsu Ban, Shintaro Yamaguchi, Ken Nishioka, Kazuno Negishi, Jun Yoshino, Toshihide Kurihara
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14711 (2022)
Cardiovascular abnormality-mediated retinal ischemia causes severe visual impairment. Retinal ischemia is involved in enormous pathological processes including oxidative stress, reactive gliosis, and retinal functional deficits. Thus, maintaining ret
Externí odkaz:
https://doaj.org/article/e6d6f342d7a84fd8a995d561e9aeab4f