Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yohei Takakura"'
Autor:
Shinya Hanashima, Yoshiki Yamaguchi, Yoshihiro Kamada, Tomoyuki Takebe, Masahiro Nagasaki, Naohito Ohno, Roberta Marchetti, Alba Silipo, Yoshiyuki Adachi, Yoshiyuki Manabe, Fabrizio Chiodo, Wataru Nihei, Kazuya Kabayama, Katsunori Tanaka, Yohei Takakura, Antonio Molinaro, Eiji Miyoshi, Hari Prasad Dulal, Hiroshi Tanaka, Koichi Fukase
Publikováno v:
Angewandte Chemie International Edition in English, 58(51), 18697-18702. John Wiley and Sons Ltd
Advanced Materials, 58(51), 18870-18875. Wiley-Blackwell
Manabe, Y, Marchetti, R, Takakura, Y, Nagasaki, M, Nihei, W, Takebe, T, Tanaka, K, Kabayama, K, Chiodo, F, Hanashima, S, Kamada, Y, Miyoshi, E, Dulal, H P, Yamaguchi, Y, Adachi, Y, Ohno, N, Tanaka, H, Silipo, A, Fukase, K & Molinaro, A 2019, ' The Core Fucose on an IgG Antibody is an Endogenous Ligand of Dectin-1 ', Advanced Materials, vol. 58, no. 51, pp. 18870-18875 . https://doi.org/10.1002/ANGE.201911875
Manabe, Y, Marchetti, R, Takakura, Y, Nagasaki, M, Nihei, W, Takebe, T, Tanaka, K, Kabayama, K, Chiodo, F, Hanashima, S, Kamada, Y, Miyoshi, E, Dulal, H P, Yamaguchi, Y, Adachi, Y, Ohno, N, Tanaka, H, Silipo, A, Fukase, K & Molinaro, A 2019, ' The core fucose on an IgG antibody is an endogenous ligand of Dectin-1 ', Angewandte Chemie International Edition in English, vol. 58, no. 51, pp. 18697-18702 . https://doi.org/10.1002/anie.201911875
Advanced Materials, 58(51), 18870-18875. Wiley-Blackwell
Manabe, Y, Marchetti, R, Takakura, Y, Nagasaki, M, Nihei, W, Takebe, T, Tanaka, K, Kabayama, K, Chiodo, F, Hanashima, S, Kamada, Y, Miyoshi, E, Dulal, H P, Yamaguchi, Y, Adachi, Y, Ohno, N, Tanaka, H, Silipo, A, Fukase, K & Molinaro, A 2019, ' The Core Fucose on an IgG Antibody is an Endogenous Ligand of Dectin-1 ', Advanced Materials, vol. 58, no. 51, pp. 18870-18875 . https://doi.org/10.1002/ANGE.201911875
Manabe, Y, Marchetti, R, Takakura, Y, Nagasaki, M, Nihei, W, Takebe, T, Tanaka, K, Kabayama, K, Chiodo, F, Hanashima, S, Kamada, Y, Miyoshi, E, Dulal, H P, Yamaguchi, Y, Adachi, Y, Ohno, N, Tanaka, H, Silipo, A, Fukase, K & Molinaro, A 2019, ' The core fucose on an IgG antibody is an endogenous ligand of Dectin-1 ', Angewandte Chemie International Edition in English, vol. 58, no. 51, pp. 18697-18702 . https://doi.org/10.1002/anie.201911875
The core fucose, a major modification of N -glycans, is implicated in immune regulation, such as the attenuation of the antibody-dependent cell-mediated cytotoxicity of antibody drugs and the inhibition of anti-tumor responses via promotion of PD-1 e
Autor:
Naoya Minamoto, Alba Silipo, Antonio Molinaro, Koichi Fukase, Katsunori Tanaka, Yohei Takakura, Hiroki Shomura, Masahiro Nagasaki, Yoshiyuki Manabe
Publikováno v:
Chemistry - An Asian Journal. 13:1544-1551
The chemical synthesis of a bisecting N-acetylglucosamine (GlcNAc)-containing N-glycan was achieved by a convergent synthetic route through [4+2] and [6+2] glycosylations. This synthetic route reduced the number of reaction steps, although the key gl
Autor:
Shinji Takamatsu, Koichi Fukase, Eiji Miyoshi, Yohei Takakura, Yoshihiro Kamada, Daisuke Yoshidome, Satomi Kasahara, Yoshiyuki Manabe, Xiaoxiao Yang
Publikováno v:
Bioorganicmedicinal chemistry. 25(11)
We developed α1,6-fucosyltransferase (FUT8) inhibitors through a diversity-oriented synthesis. The coupling reaction between the fucose unit containing alkyne and the guanine unit containing sulfonyl azide under various conditions afforded a series