Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Yohei Nishi"'
Autor:
Ichiji Namatame, Kana Ishii, Takashi Shin, Daisuke Shimojo, Yukiko Yamagishi, Hidemitsu Asano, Yuuki Kishimoto, Hiromitsu Fuse, Yohei Nishi, Hidetoshi Sakurai, Tatsutoshi Nakahata, Haruna Sasaki-Iwaoka
Publikováno v:
SLAS Technology, Vol 28, Iss 5, Pp 351-360 (2023)
Due to their physiological relevance, cell-based assays using human-induced pluripotent stem cell (iPSC)-derived cells are a promising in vitro pharmacological evaluation system for drug candidates. However, cell-based assays involve complex processe
Externí odkaz:
https://doaj.org/article/4ec6426974f04615a35a7e1621a58788
Autor:
Ryo Ito, Azuma Kimura, Yurie Hirose, Yu Hatano, Atsushi Mima, Shin-Ichi Mae, Yamato Keidai, Toshihiro Nakamura, Junji Fujikura, Yohei Nishi, Akira Ohta, Taro Toyoda, Nobuya Inagaki, Kenji Osafune
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract For pluripotent stem cell (PSC)-based regenerative therapy against diabetes, the differentiation efficiency to pancreatic lineage cells needs to be improved based on the mechanistic understanding of pancreatic differentiation. Here, we aimed
Externí odkaz:
https://doaj.org/article/df2cb19d80214e9ca8bdf82af4846cfd
Autor:
Keiko Imamura, Yasuteru Sakurai, Takako Enami, Ran Shibukawa, Yohei Nishi, Akira Ohta, Tsugumine Shu, Jitsutaro Kawaguchi, Sayaka Okada, Thomas Hoenen, Jiro Yasuda, Haruhisa Inoue
Publikováno v:
FEBS Open Bio, Vol 11, Iss 5, Pp 1452-1464 (2021)
Human pathogenic RNA viruses are threats to public health because they are prone to escaping the human immune system through mutations of genomic RNA, thereby causing local outbreaks and global pandemics of emerging or re‐emerging viral diseases. W
Externí odkaz:
https://doaj.org/article/4a4e279441aa4abbb5afc6d67541b2f8
Autor:
Mio Iwasaki, Yuka Kawahara, Chikako Okubo, Tatsuya Yamakawa, Michiko Nakamura, Tsuyoshi Tabata, Yohei Nishi, Megumi Narita, Akira Ohta, Hirohide Saito, Takuya Yamamoto, Masato Nakagawa, Shinya Yamanaka, Kazutoshi Takahashi
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104289- (2022)
Summary: The effects of transcription factors on the maintenance and differentiation of human-induced or embryonic pluripotent stem cells (iPSCs/ESCs) have been well studied. However, the importance of posttranscriptional regulatory mechanisms, which
Externí odkaz:
https://doaj.org/article/4e083f7c47a34a7694fd39ebde05df31
Publikováno v:
Stem Cell Research, Vol 24, Iss C, Pp 61-68 (2017)
While pancreatic islet transplantation achieves insulin independence in type 1 diabetes (T1D) patients, its widespread application is limited by donor tissue scarcity. Pancreatic progenitor cells (PPCs) give rise to all cell types in the pancreas dur
Externí odkaz:
https://doaj.org/article/a43bb141675744d4b06a3b0ac06b8ef1
Autor:
Maho Yagi-Utsumi, Sumi Yoshikawa, Yoshiki Yamaguchi, Yohei Nishi, Eiji Kurimoto, Yoshihito Ishida, Takayuki Homma, Jun Hoseki, Yoshimi Nishikawa, Takaki Koide, Kazuhiro Nagata, Koichi Kato
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45930 (2012)
Heat shock protein 47 (Hsp47) acts as a client-specific chaperone for collagen and plays a vital role in collagen maturation and the consequent embryonic development. In addition, this protein can be a potential target for the treatment of fibrosis.
Externí odkaz:
https://doaj.org/article/5dae327d8d044f7b90243b47228b1f84
Autor:
Kazuki Yamamoto, MD, PhD, Haruhiro Inoue, MD, PhD, FASGE, Ippei Tanaka, MD, MPH, Kei Ushikubo, MD, Daisuke Azuma, MD, Hiroki Okada, MD, Yohei Nishikawa, MD, PhD, Yuto Shimamura, MD, PhD, FASGE
Publikováno v:
VideoGIE, Vol 9, Iss 9, Pp 389-392 (2024)
Externí odkaz:
https://doaj.org/article/67f8355412214fd5a7e8d968ad830390
Autor:
Kenji Osafune, Tatsutoshi Nakahata, Toshikazu Araoka, Akira Ohta, Hiraku Tsujimoto, Yohei Nishi
Publikováno v:
Biochemical and Biophysical Research Communications. 558:231-238
Several groups have developed in vitro expansion cultures for mouse metanephric nephron progenitor cells (NPCs) using cocktails of small molecules and growth factors including BMP7. However, the detailed mechanisms by which BMP7 acts in the NPC expan
Autor:
Yohei Nishida, Yusuke Hashimoto, Kumi Orita, Kazuya Nishino, Takuya Kinoshita, Ken Iida, Hiroaki Nakamura
Publikováno v:
Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, Vol 37, Iss , Pp 27-32 (2024)
Background/objective: Cartilage oligomeric matrix protein (COMP) has utility as a diagnostic marker for osteoarthritis (OA). Our previous study revealed that the serum COMP level can be used to detect early cartilage change in non-OA patients with an
Externí odkaz:
https://doaj.org/article/f1827036943a43b2bd5ba22acf3215d2
Autor:
Kazuki Yamamoto, MD, PhD, Haruhiro Inoue, MD, PhD, FASGE, Ippei Tanaka, MD, MPH, Kei Ushikubo, MD, Hiroki Okada, MD, Yohei Nishikawa, MD, Kaori Owada, MD, Yuto Shimamura, MD, PhD, FASGE
Publikováno v:
VideoGIE, Vol 9, Iss 7, Pp 303-308 (2024)
Externí odkaz:
https://doaj.org/article/2b7a59c893094ebdb8c68341efcaf35e