Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Yohei Niikura"'
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112568- (2023)
Summary: The centromere is essential for ensuring high-fidelity transmission of chromosomes. CENP-A, the centromeric histone H3 variant, is thought to be the epigenetic mark of centromere identity. CENP-A deposition at the centromere is crucial for p
Externí odkaz:
https://doaj.org/article/419be356bb984dfd8fb34254d914bb6a
Publikováno v:
Cell Reports, Vol 15, Iss 1, Pp 61-76 (2016)
The presence of chromatin containing the histone H3 variant CENP-A dictates the location of the centromere in a DNA sequence-independent manner. But the mechanism by which centromere inheritance occurs is largely unknown. We previously reported that
Externí odkaz:
https://doaj.org/article/f9c605fb12aa48968ab7bbf0e3278b1a
Publikováno v:
Molecules, Vol 24, Iss 3, p 402 (2019)
The centromere plays an essential role in accurate chromosome segregation, and the chromosomal location of the centromere is determined by the presence of a histone H3 variant, centromere protein A (CENP-A), in centromeric nucleosomes. However, the p
Externí odkaz:
https://doaj.org/article/a9cfeb8e26f64906bc1f5c2f7658fa19
Autor:
Yohei Niikura, Katsumi Kitagawa
Publikováno v:
Hydrolases
Centromeric CENP-A, a variant of histone H3, plays a central role in proper chromosome segregation and its function is highly conserved among different species. In most species with regional centromeres, an active centromere relies not on defined DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969942eb98c1d7e037c6259b8e05230f
https://mts.intechopen.com/articles/show/title/e3-ligase-for-cenp-a-part-2-
https://mts.intechopen.com/articles/show/title/e3-ligase-for-cenp-a-part-2-
Autor:
Yohei Niikura, Katsumi Kitagawa
Publikováno v:
Hydrolases
CENP-A is a centromere-specific histone H3 variant that is required to ensure kinetochore assembly for proper chromosome segregation and its function is highly conserved among different species including budding yeast, Saccharomyces cerevisiae. The b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64593db1dfd7bada52fdbfd24f8b6903
https://mts.intechopen.com/articles/show/title/e3-ligase-for-cenp-a-part-1-
https://mts.intechopen.com/articles/show/title/e3-ligase-for-cenp-a-part-1-
Autor:
Lei Fang, Katsumi Kitagawa, Peizhao Li, Risa Kitagawa, Yan Guo, Ju You, Yohei Niikura, Yao Xi
Publikováno v:
Journal of visualized experiments : JoVE. (160)
Studying the structure and the dynamics of kinetochores and centromeres is important in understanding chromosomal instability (CIN) and cancer progression. How the chromosomal location and function of a centromere (i.e., centromere identity) are dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3b238ae11e3cbdb54c7a296553c859
https://pubmed.ncbi.nlm.nih.gov/32597847
https://pubmed.ncbi.nlm.nih.gov/32597847
Autor:
Katsumi Kitagawa, Yohei Niikura
Publikováno v:
Heat Shock Proteins ISBN: 9783030231576
SGT1/SUGT1, a co-chaperone of HSP90, is involved in multiple cellular activities including cullin E3 ubiquitin ligase activity. In various species, SGT1 homologs have been identified, indicating that SGT1 genes and proteins are highly conserved. SGT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::575dc699a12b2f92d0fee6ed4f54b4ab
https://doi.org/10.1007/978-3-030-23158-3_16
https://doi.org/10.1007/978-3-030-23158-3_16
Publikováno v:
Cell Reports, Vol 15, Iss 1, Pp 61-76 (2016)
SummaryThe presence of chromatin containing the histone H3 variant CENP-A dictates the location of the centromere in a DNA sequence-independent manner. But the mechanism by which centromere inheritance occurs is largely unknown. We previously reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b2b0f456b74493d773f7168a1a32cb
https://doi.org/10.1016/j.celrep.2016.03.010
https://doi.org/10.1016/j.celrep.2016.03.010
Publikováno v:
Dev Cell
CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity, but how CENP-A is deposited at the centromere remains obscure. We previously reported that CENP-A K124 ubiquitylation, mediated by the CUL4A-RBX1-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f535fbfc088f2a153beb13fb99203f
https://pubmed.ncbi.nlm.nih.gov/31550462
https://pubmed.ncbi.nlm.nih.gov/31550462
Publikováno v:
Cell Cycle
The centromere plays an essential role in accurate chromosome segregation, and defects in its function lead to aneuploidy and thus cancer. The centromere-specific histone H3 variant CENP-A is proposed to be the epigenetic mark of the centromere, as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fc3c0fa45f4ab3f89dbf833ccd8397
https://pubmed.ncbi.nlm.nih.gov/28816574
https://pubmed.ncbi.nlm.nih.gov/28816574