Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Yohei Matsunaga"'
Autor:
Yohei Matsunaga, Hiroshi Qadota, Nasab Ghazal, Leila Lesanpezeshki, Till Dorendorf, Jasmine C. Moody, Arnaud Ahier, Courtney J. Matheny, Siva A. Vanapalli, Steven Zuryn, Olga Mayans, Jennifer Q. Kwong, Guy M. Benian
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract UNC-89 is a giant sarcomeric M-line protein required for sarcomere organization and optimal muscle function. UNC-89 contains two protein kinase domains, PK1 and PK2, separated by an elastic region. Here we show that PK2 is a canonical kinase
Externí odkaz:
https://doaj.org/article/bba44bd80c7247d28d8e36412ab42597
Autor:
Hiroshi Qadota, Annie McPherson, Rachel Corbitt, Evan Kelton Dackowski, Yohei Matsunaga, Andres F Oberhauser, Guy M Benian
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 7 (2022)
AbstractIntegrin plays a crucial role in the attachment of cells to the extracellular matrix. Integrin recruits many proteins intracellularly, including a 4-protein complex (kindlin, ILK, PINCH, and parvin). Caenorhabditis elegansCaenorhabditis elega
Externí odkaz:
https://doaj.org/article/eea7a71f2491439e8ffcd613729671da
Autor:
Jasmine C. Moody, Hiroshi Qadota, April R. Reedy, C. Denise Okafor, Niveda Shanmugan, Yohei Matsunaga, Courtney J. Christian, Eric A. Ortlund, Guy M. Benian
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
PIX proteins activate the small GTPases Rac and Cdc42, and are known to have numerous functions in a variety of cell types. Using a genetic screen in C. elegans, the authors find that PIX-1 is required for the assembly or stability of integrin adhesi
Externí odkaz:
https://doaj.org/article/97b17489d39b4b8787aa01fe4c4441f9
Autor:
Daniel Porto, Yohei Matsunaga, Barbara Franke, Rhys M Williams, Hiroshi Qadota, Olga Mayans, Guy M Benian, Hang Lu
Publikováno v:
eLife, Vol 10 (2021)
The force-induced unfolding and refolding of proteins is speculated to be a key mechanism in the sensing and transduction of mechanical signals in the living cell. Yet, little evidence has been gathered for its existence in vivo. Prominently, stretch
Externí odkaz:
https://doaj.org/article/3cbb59f548534da7ac17b2502b6e4447
Autor:
Yohei Matsunaga, Tsuyoshi Kawano
Publikováno v:
AIMS Biophysics, Vol 5, Iss 4, Pp 217-230 (2018)
Insulin and insulin-like peptides (ILPs) are conserved in living organisms to modulate homeostasis by functioning as ligands. For understanding of molecular mechanisms regulated by the ligands, the nematode Caenorhabditis elegans is a good model sinc
Externí odkaz:
https://doaj.org/article/e324aaf6f5734981ab9921ed0e5002f4
Autor:
Yohei Matsunaga, Yoko Honda, Shuji Honda, Takashi Iwasaki, Hiroshi Qadota, Guy M. Benian, Tsuyoshi Kawano
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Insulin-like peptides INS-7 and INS-35 suppress larval diapause in Caenorhabditis elegans via unknown mechanism. Here, Matsunaga et al.show that the secretory polarity of both peptides changes in diapause, when these peptides are secreted into the in
Externí odkaz:
https://doaj.org/article/899ec1d136314117807790e501810fff
Autor:
Masahiro Ono, Kenjiro Matsushita, Sho Maega, Naoto Asano, Yohei Matsunaga, Tomohiro Bito, Takashi Iwasaki, Tsuyoshi Kawano
Publikováno v:
Biochemical and Biophysical Research Communications. 660:28-34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50a0a9473abf0498f788c02c1bc0b306
https://doi.org/10.1016/j.bbrc.2023.03.080
https://doi.org/10.1016/j.bbrc.2023.03.080
Autor:
Risako Une, Natsumi Kageyama, Masahiro Ono, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 87:171-178
The FMRFamide-like peptides (FLPs) are conserved in both free-living and parasitic nematodes. This molecular genetic study verified the relevance of the flp-1 gene, which is conserved in many nematode species, to the larval development of the free-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55e1a9a0e0dc5919dfc0604a92c07f2
https://doi.org/10.1093/bbb/zbac187
https://doi.org/10.1093/bbb/zbac187
Autor:
Guy M. Benian, Courtney J. Christian, Eric A. Ortlund, Jasmine C. Moody, C. Denise Okafor, Niveda Shanmugan, April R. Reedy, Hiroshi Qadota, Yohei Matsunaga
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
PIX proteins are guanine nucleotide exchange factors (GEFs) that activate Rac and Cdc42, and are known to have numerous functions in various cell types. Here, we show that a PIX protein has an important function in muscle. From a genetic screen in C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9af9a39f37c8ab692197dd068f7429c
http://link.springer.com/article/10.1038/s41467-020-18852-4
http://link.springer.com/article/10.1038/s41467-020-18852-4
Autor:
Yohei Matsunaga, Hiroshi Qadota, Hang Lu, Barbara Franke, Daniel A. Porto, Rhys M. Williams, Olga Mayans, Guy M. Benian
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
The force-induced unfolding and refolding of proteins is speculated to be a key mechanism in the sensing and transduction of mechanical signals in the living cell. Yet, little evidence has been gathered for its existence in vivo. Prominently, stretch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2e68091135ed8a24a81b4b960c074a
http://europepmc.org/articles/PMC8523150
http://europepmc.org/articles/PMC8523150