Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Yohei MIKAMI"'
Autor:
Ryoya Sakakibara, Shinya Sugimoto, Kaoru Takabayashi, Hiroki Kiyohara, Yusuke Wakisaka, Yuta Kaieda, Miho Kawaida, Yusuke Yoshimatsu, Tomohisa Sujino, Naoki Hosoe, Motohiko Kato, Masayuki Shimoda, Yohei Mikami, Yasushi Iwao, Takanori Kanai
Publikováno v:
Intestinal Research, Vol 22, Iss 4, Pp 428-438 (2024)
Background/Aims Poorly differentiated adenocarcinoma, signet-ring cell carcinoma, and mucinous adenocarcinoma (por/sig/muc), which are considered to be histologic subtypes with a poor prognosis, occur more frequently with colitis-associated cancer th
Externí odkaz:
https://doaj.org/article/ad7fa628e5684fe7aa330fa029cb3663
Autor:
Fumie Shimada, Yusuke Yoshimatsu, Tomohisa Sujino, Tomohiro Fukuda, Yasuhiro Aoki, Yukie Hayashi, Anna Tojo, Takaaki Kawaguchi, Hiroki Kiyohara, Shinya Sugimoto, Kosaku Nanki, Yohei Mikami, Kentaro Miyamoto, Kaoru Takabayashi, Naoki Hosoe, Motohiko Kato, Haruhiko Ogata, Makoto Naganuma, Takanori Kanai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Indigo naturalis is an effective treatment for ulcerative colitis. However, long-term use of indigo naturalis causes adverse events, such as pulmonary hypertension. The natural history of patients with ulcerative colitis who discontinued ind
Externí odkaz:
https://doaj.org/article/6c997f5690914229aa3941149ed3c29a
Autor:
Anna Tojo, Tomohisa Sujino, Yukie Hayashi, Kenji J L Limpias Kamiya, Moe Sato, Sakurai Hinako, Yusuke Yoshimatsu, Satoshi Kinoshita, Hiroki Kiyohara, Yohei Mikami, Kaoru Takabayashi, Motohiko Kato, Haruhiko Ogata, Takanori Kanai, Naoki Hosoe
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Objective This study aimed to evaluate the use of video capsule endoscopy (VCE) in patients with obscure gastrointestinal bleeding (OGIB), compare cases of overt and occult OGIB, assess the rates of balloon‐assisted enteroscopy (BAE) inter
Externí odkaz:
https://doaj.org/article/c47014fe8bb54f13a6ec9ce2260de1b2
Downregulation of chemokine receptor 9 facilitates CD4+CD8αα+ intraepithelial lymphocyte development
Autor:
Keiko Ono, Tomohisa Sujino, Kentaro Miyamoto, Yosuke Harada, Satoshi Kojo, Yusuke Yoshimatsu, Shun Tanemoto, Yuzo Koda, Jiawen Zheng, Kazutoshi Sayama, Tsuyoshi Koide, Toshiaki Teratani, Yohei Mikami, Kaoru Takabayashi, Nobuhiro Nakamoto, Naoki Hosoe, Mariya London, Haruhiko Ogata, Daniel Mucida, Ichiro Taniuchi, Takanori Kanai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Intestinal intraepithelial lymphocytes (IELs) reside in the gut epithelial layer, where they help in maintaining intestinal homeostasis. Peripheral CD4+ T cells can develop into CD4+CD8αα+ IELs upon arrival at the gut epithelium via the la
Externí odkaz:
https://doaj.org/article/f3798e0a3c1041ce9d72da327e0971b3
Autor:
Yasuhiro Aoki, Hiroki Kiyohara, Yohei Mikami, Kosaku Nanki, Takaaki Kawaguchi, Yusuke Yoshimatsu, Shinya Sugimoto, Tomohisa Sujino, Kaoru Takabayashi, Naoki Hosoe, Haruhiko Ogata, Yasushi Iwao, Takanori Kanai
Publikováno v:
Intestinal Research, Vol 21, Iss 3, Pp 318-327 (2023)
Background/Aims Thromboprophylaxis is recommended for hospitalized patients with inflammatory bowel disease (IBD) in Western countries, although it is selectively administered to high-risk patients in East Asia. A central venous catheter (CVC) is com
Externí odkaz:
https://doaj.org/article/bbb49d5b7abf4910b605c0ac0285989a
Autor:
Masataka Ichikawa, Nobuhiro Nakamoto, Sharon Kredo-Russo, Eyal Weinstock, Iddo Nadav Weiner, Efrat Khabra, Noa Ben-Ishai, Dana Inbar, Noga Kowalsman, Ron Mordoch, Julian Nicenboim, Myriam Golembo, Naomi Zak, Jagoda Jablonska, Hila Sberro-Livnat, Sharon Navok, Nufar Buchshtab, Takahiro Suzuki, Kentaro Miyamoto, Toshiaki Teratani, Sota Fujimori, Yoshimasa Aoto, Mikiko Konda, Naoki Hayashi, Po-Sung Chu, Nobuhito Taniki, Rei Morikawa, Ryosuke Kasuga, Takaya Tabuchi, Shinya Sugimoto, Yohei Mikami, Atsushi Shiota, Merav Bassan, Takanori Kanai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Primary sclerosing cholangitis (PSC) is characterized by progressive biliary inflammation and fibrosis. Although gut commensals are associated with PSC, their causative roles and therapeutic strategies remain elusive. Here we detect abundant
Externí odkaz:
https://doaj.org/article/8e9c667b9e3f4258ae810e7f1e3cb2ef
Autor:
Satoko Umeda, Tomohisa Sujino, Kentaro Miyamoto, Yusuke Yoshimatsu, Yosuke Harada, Keita Nishiyama, Yoshimasa Aoto, Keika Adachi, Naoki Hayashi, Kimiko Amafuji, Nobuko Moritoki, Shinsuke Shibata, Nobuo Sasaki, Masashi Mita, Shun Tanemoto, Keiko Ono, Yohei Mikami, Jumpei Sasabe, Kaoru Takabayashi, Naoki Hosoe, Toshihiko Suzuki, Toshiro Sato, Koji Atarashi, Toshiaki Teratani, Haruhiko Ogata, Nobuhiro Nakamoto, Daisuke Shiomi, Hiroshi Ashida, Takanori Kanai
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 6, Pp 1011-1031 (2023)
Background & Aims: D-amino acids, the chiral counterparts of protein L-amino acids, were primarily produced and utilized by microbes, including those in the human gut. However, little was known about how orally administered or microbe-derived D-amino
Externí odkaz:
https://doaj.org/article/3561896e2e8b4eb4a814259518b66ff8
Autor:
Kentaro Miyamoto, Tomohisa Sujino, Yosuke Harada, Hiroshi Ashida, Yusuke Yoshimatsu, Yuki Yonemoto, Yasuhiro Nemoto, Michio Tomura, Hassan Melhem, Jan Hendrik Niess, Toshihiko Suzuki, Toru Suzuki, Shohei Suzuki, Yuzo Koda, Ryuichi Okamoto, Yohei Mikami, Toshiaki Teratani, Kenji Tanaka, Akihiko Yoshimura, Toshiro Sato, Takanori Kanai
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 113005- (2023)
Summary: The intricate interplay between gut microbes and the onset of experimental autoimmune encephalomyelitis (EAE) remains poorly understood. Here, we uncover remarkable similarities between CD4+ T cells in the spinal cord and their counterparts
Externí odkaz:
https://doaj.org/article/6632c89448fd46648ba14a7d12c1c18d
Autor:
Sota Fujimori, Po-Sung Chu, Toshiaki Teratani, Yosuke Harada, Takahiro Suzuki, Takeru Amiya, Nobuhito Taniki, Ryosuke Kasuga, Yohei Mikami, Yuzo Koda, Masataka Ichikawa, Takaya Tabuchi, Rei Morikawa, Karin Yamataka, Fumie Noguchi, Hanako Tsujikawa, Yutaka Kurebayashi, Michiie Sakamoto, Takanori Kanai, Nobuhiro Nakamoto
Publikováno v:
JHEP Reports, Vol 5, Iss 7, Pp 100757- (2023)
Background & Aims: B-cell depletion therapy with an anti-CD20 is an effective treatment strategy for patients with refractory autoimmune hepatitis (AIH). However, the mechanisms underlying B-cell action are unclear. Methods: Herein, we used the adeno
Externí odkaz:
https://doaj.org/article/15879773b4c14ca5ad1fed278c126c75
Autor:
Yoichi Takimoto, Po-sung Chu, Nobuhiro Nakamoto, Yuya Hagihara, Yohei Mikami, Kentaro Miyamoto, Rei Morikawa, Toshiaki Teratani, Nobuhito Taniki, Sota Fujimori, Takahiro Suzuki, Yuzo Koda, Rino Ishihara, Masataka Ichikawa, Akira Honda, Takanori Kanai
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106220- (2023)
Summary: The fate of resolution of liver fibrosis after withdrawal of liver injury is still incompletely elucidated. Toll-like receptor 4 (TLR4) in tissue fibroblasts is pro-fibrogenic. After withdrawal of liver injury, we unexpectedly observed a sig
Externí odkaz:
https://doaj.org/article/548f49159bf04a07a8a3cc50908067f5