Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yohei Kubota"'
Autor:
Yohei Kubota, Kohei Shitara
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Claudins (CLDNs) are a family of major membrane proteins that form components of tight junctions. In normal tissues, CLDNs seal the intercellular space in the epithelial sheets to regulate tissue permeability, paracellular transport, and signal trans
Externí odkaz:
https://doaj.org/article/fc51a5b9dcd5462b9e6cec913f61b4a9
Autor:
Yohei Kubota, Toh Yoon Ezekiel Wong
Publikováno v:
Case Reports in Medicine, Vol 2018 (2018)
When elderly patients are prescribed many different medications, the risk for developing serious adverse events should be kept in mind. One of these adverse events is agranulocytosis, which, although rare, can be life-threatening if left untreated. T
Externí odkaz:
https://doaj.org/article/d57ded2ea36a46c387586a20ee7cfe04
Autor:
Yohei Kubota, Ezekiel Wong Toh Yoon
Publikováno v:
Case Reports in Medicine, Vol 2018 (2018)
Externí odkaz:
https://doaj.org/article/cbc7f578f05344fc88fa7c6a7c608380
Autor:
Yu Aoki, Akihito Kawazoe, Yohei Kubota, Keigo Chida, Saori Mishima, Daisuke Kotani, Yoshiaki Nakamura, Yasutoshi Kuboki, Hideaki Bando, Takashi Kojima, Toshihiko Doi, Takayuki Yoshino, Takeshi Kuwata, Kohei Shitara
Publikováno v:
International Journal of Clinical Oncology. 27:1413-1420
Although several randomized trials (RCTs) showed survival benefits of immune checkpoint inhibitor (ICI) plus first-line chemotherapy for advanced gastric or gastroesophageal cancer (AGC), these trials could enroll patients who fulfilled the strict el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d265b49de9781bc3c70684ac09058b
https://doi.org/10.1007/s10147-022-02200-1
https://doi.org/10.1007/s10147-022-02200-1
Autor:
Kohei Shitara, Takeshi Kuwata, Genichiro Ishii, Takayuki Yoshino, Toshihiko Doi, Takashi Kojima, Hiroya Taniguchi, Yasutoshi Kuboki, Daisuke Kotani, Yoshiaki Nakamura, Kentaro Sawada, Saori Mishima, Akinori Sasaki, Akihito Kawazoe, Yohei Kubota
Purpose:We evaluated the association between molecular subtypes of advanced gastric cancer (AGC) and the efficacy of standard chemotherapy or immune checkpoint inhibitors.Experimental Design:Patients with AGC who received systemic chemotherapy from O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cac872cbae1d90be2a137ecb27a30e
https://doi.org/10.1158/1078-0432.c.6529284
https://doi.org/10.1158/1078-0432.c.6529284
Autor:
Kohei Shitara, Takeshi Kuwata, Genichiro Ishii, Takayuki Yoshino, Toshihiko Doi, Takashi Kojima, Hiroya Taniguchi, Yasutoshi Kuboki, Daisuke Kotani, Yoshiaki Nakamura, Kentaro Sawada, Saori Mishima, Akinori Sasaki, Akihito Kawazoe, Yohei Kubota
Clinical and molecular features of responders to anti-PD-1 therapy in each subtype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d2e16544a55c5302c2037dceb79732
https://doi.org/10.1158/1078-0432.22476063.v1
https://doi.org/10.1158/1078-0432.22476063.v1
Publikováno v:
Cancer management and research. 14
Recently, immune checkpoint inhibitor (ICI), such as anti-programmed cell death-1 (PD-1) or programmed cell death ligand-1 (PD-L1) monoclonal antibodies, has provided clinical benefits in various cancer types including advanced gastric cancer (AGC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec57182b507b7bd14228a53322bfd2cb
https://pubmed.ncbi.nlm.nih.gov/36275782
https://pubmed.ncbi.nlm.nih.gov/36275782
Recently, immune checkpoint inhibitors (ICIs) have emerged as new standard treatment in various cancer types including advanced gastric cancer (AGC), showing favor clinical benefit in some population. More recently, ICIs combined with cytotoxic agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::524a08ffa9ae103d4b83b82d846ff47a
https://doi.org/10.1007/13905_2021_5
https://doi.org/10.1007/13905_2021_5
Autor:
Yuka Takahashi, Hiroyuki Nakanishi, Mao Okada, Jun Itakura, Kaoru Tsuchiya, Yasuyuki Komiyama, Masayuki Kurosaki, Takao Shimizu, Mayu Higuchi, Yohei Kubota, Yutaka Yasui, Keiya Watakabe, Nobuharu Tamaki, Wan Wang, Nobuyuki Enomoto, Namiki Izumi, Hitomi Takada, Kenta Takaura
Publikováno v:
Hepatology Research. 48:1131-1139
AIM The aim of this study is to clarify the value of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA+ -M2BP) for predicting hepatocellular carcinoma (HCC) in chronic hepatitis C patients who achieved sustained virologic respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::285f9a2c1be0a62751b189ac321feeea
https://doi.org/10.1111/hepr.13233
https://doi.org/10.1111/hepr.13233
Autor:
Tsuguru Hayashi, Takaya Takeguchi, Wan Wang, Yasuyuki Komiyama, Yuko Takeguchi, Mayu Higuchi, Hiroyuki Nakanishi, Namiki Izumi, Yohei Kubota, Hitomi Takada, Yoshiro Himeno, Nobuyuki Enomoto, Yasuhiro Asahina, Mao Okada, Tomoyuki Goto, Jun Itakura, Masayuki Kurosaki, Yuka Takahashi, Nobuharu Tamaki, Yutaka Yasui, Kenta Takaura, Kaoru Tsuchiya
Publikováno v:
Hepatology Research. 48:442-450
Aim Intermediate-stage hepatocellular carcinoma varies widely in tumor burden and liver function. This study aimed to clarify the importance of subclassification by the up-to-seven criteria in both clinical course and liver function deterioration in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::858986d53a478be13439733d4af18888
https://doi.org/10.1111/hepr.13048
https://doi.org/10.1111/hepr.13048